Considering the table-type ballistocardiography as a forced vibration of a vibrating system which had second degree of freedom, a new method which eliminated simply the distortions of ballistocardiograms was mentioned and the correlating problems were discussed.

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The author have induced pulmonary embolism by intravenous injection of 1% suspension of Lycopodium Spores in physiologic saline, and studied the hemodynamic changes in pulmonary circulation.1) 9 dogs were catheterized and measured the pulmonary arterial pressure, cardiac output and circulating bloodvolume before and after the embolism. Each of 6 dogs showed temporary arterial hypertension (maximal elevation in meanpressure was 4.1 times of control level) which have declined gradually and 38 minutcs (average) after embolism returned to the control pressure level. Hematocrit % have decreased and suggested the increase in blood plasma volume. Interpretation of T-1824 extrapolating curve have proved the mobilisation of depot blood.2) 9 dogs were repeatedly induced pulmonary embolism at intervalls of 7-10 days and catheterized before and after the first ambolism and 3-4 months later. Pulmonary arterial pressure have elevated slightly, but showed no correlation with time duration of embolism. Cardiac output have showed no or slight increase. Hematocrit %, red blood cell count and hemoglobin % have increased every time. All dogs showed increases in circulating blood volume, and hypertrophies of right ventricular walls.3) The facts that the pulmonary arterial hypertension is a temporary one, and that the absence of expected marked pulmonary arterial hypertension after repeated pulmonary embolism and the abscence of the decrease of pulmonary blood flow, suggests the vast reserve bypassing bloodways in the pulmonary vascular bed.

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The results of the investigation to know whether the potential of the central terminal is as small as neglisible clinically or not, and to know mush potential it is, are as follows : (1) To get precise data of potential of the central terminal with these two methods, the body must be laid on its back with its limbs out of water preventing them from getting wet.(2) The potential of the central terminal measured with Wilson's and with Shimizu-Fujito's method respectively in 20 patients (12 patients with normal heart and 8 with enlarged heart) shows 0.16∼0.55mV in the former and 0.09∼0.50 mV in the latter. Thus, there may be such a case in which the potential is not always below 0.30 mV as Wilson says.(3) In the unipolar chest lead in which the potential is too large to compare with that of central terminal, the latter may be disregarded to a certain extent. But in the unipolar limb lead with its small potential difference, the potential of central terminal can not be disregarded.(4) These results indicate that it is very difficult to say which one of these two methods may have more ideal potential of the central terminal as a zero potential.

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(1) 700 cases of non-surgically treated patients with pulmonary tuberculosis were examined for abnormalities in position type and T wave by means of φ-pattern. Incidence of such abnormalities was statistically correlated to erythrocyte sedimentation rate and blood pressure.(2) Erythrocyte sedimentation rate below 10mm was most populat throughout the entire group. Normal type was popular among individuals with nearly normal erythrocyte sedimentation rate. Vertical type and right axis deviation were popular among those with increased sedimentation rate.(3) Normal T wave occurred frequently in association with normal sedimentation rate, wile abnormal T wave occurred frequently in association with increased sedimentation rate. This held both for frequency and grade.(4) Normal blood pressure was recorded from 70% of the entire group examined. In association with vertical type and right axis deviation many cases showed lowered systolic blood pressure.(5) Normal T wave was often asociated with normal blood pressure, and abnormal T wave with hypotension. This held both for ferquency of incidence and grade.(6) The author postulates that tubercle bacillus toxin causes a generalized atonia of the cardiovascular system, hence vertical type, right axis deviation and T abnormalities.

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Among the various causes for the development of the pulmonary edema, the most important one seemed to be the rise of the hydrostatic pressure level around the pulmonary capillaries. The minimum of the hydrostatic level which leads to the pulmonary edema has been discussed, and it is believed that it would be differently effected by some other causes.Tetraethylammonium bromide (TEAB) has been supposed to get the pulmonary artery pressure fall and restrain the heart in its function. But I will report here on my own experience in which I clinically observed the pulmonary edema with the remarked pulmonary hypertension. It was caused quite unexpectedly, when I injected 200 mg of TEAB into muscles while the catheter was inserted into the pulmonary artery.The first cases was a patient with aortic insufficiency and the second case was that of essential hypertension. The both cases showed clinically pulmonary edema in 3 to 5 minutes after TEAB injection. WP of the first case was 27 mmHg and mean pulmonary artery pressure was 42.5 mmHg before injection. while on the other hand WP was 35 mmHg and pulmonary artery pressure was 57 mmHg during fit. By removal of catheter and squating in Japanese fashion, fit was dettered. WP of the second case was 9 mmHg and the mean pulmonary artery pressure was 21.5 mmHg before injection, while on the other hand WP was 33 mmHg and pulmonary artery pressure was 54.5 mmHg during fit. In this case the injection of Theophyllin Etylendiamine 250 mg intravenously caused the fall of WP and at the same time the case was bettered. In both cases, In observed that in accordance with WP elevation, the pressure gradient between the pulmonary artery pressure and WP showed the tendency to increase. I can not explain the rising cause of pulmonary blood pressure after TEAB injection. The rising of WP means the rising of the pulmonary small vein pressure.When WP was elevated up to more than a certain level, the pulmonary edema was observed to develope rapidly.According to the elevation of WP, pressure gradient between pulmonary artery pressure and WP increased. This should be reduced to the increase of resistance on the pulmonary small artery, which is believed to be the protecting reaction against the pulmonary edema.

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On the isolated toad heart the author studied the relationships between the QT interval and the heart work, comparing before with after the addition of various medicaments (Digitalis, Sekigaigoseishi-kiso, Chloralum hydratum, Aethylalkohol, Bile of toad, 1/2 Ca Ringer's Solution and 2K 1/2 Ca Ringer's Solution).(1) When the heart work was increased after the addition of the medicament, the QT interval was prolonged, unchanged or shortened according to the kind and the concentration of the medicament.(2) When the heart work was unchanged after the addition of the medicament, the QT interval was prolonged or shortened after the addition.(3) When the heart work was decreased after the addition of the medicament, the QT interval after the addition was shortened in the majority of cases, but prolonged in some cases.(4) From the above-mentioned data, it may be concluded as follows. Namely, (i) on the toad heart under the action of the medicament to influence the heart function, the QT interval and the heart work are not uniformally related. (ii) Consequently, under the action of the medicament to influence the heart function, not only the QT interval, but also another factor (the electric quantity in unit time), as considered from "Chaindoublets Theory (Maekawa)", have to be taken into consideration in order to judge the change in the heart work.

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