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Volume 2 (1955)
- Issue 4 Pages 247-
- Issue 3 Pages 171-
- Issue 2 Pages 89-
- Issue 1 Pages 1-
Volume 2, Issue 1
Displaying 1-10 of 10 articles from this issue
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FUJIO YOSHIMURA, KIMIO TSUNODA1955 Volume 2 Issue 1 Pages 1-12
Published: 1955
Released on J-STAGE: January 25, 2011
JOURNAL FREE ACCESSThe subcutaneous administration of Na-tartrate caused a picture of definite degeneration or necrosis in proximal convolution epithelial cells of the rabbit kidney.This, together with the data in the preceding communication (Yoshimura and Negishi, 1954) that the chemical did not influence upon the vasopressoreffect of kidney extract, casts a doubt on the Friedman and Kaplans'proximal convolution theory regarding the site of renin formation.
The subcutaneous administration of the chemical produced the evident sign of hypergranulation and endocrine activity in juxtaglomerular cells of the rabbit which contain no granules in normal state. This is considered to sufficiently weakened the ground of Goormaghtigh's juxtaglomerular cell theory coticerning the site of renin formation.
The subcutaneous administration of the chemical did not affect significantly the dark cells in the junctional and the collecting tubules, but some changes were recognized in them in both the inner striated portion of outer zone and inner zone of medulla.View full abstractDownload PDF (8087K) -
TAKESHI NAKAO, YOSHIO AIZAWA1955 Volume 2 Issue 1 Pages 13-22
Published: 1955
Released on J-STAGE: January 25, 2011
JOURNAL FREE ACCESSDownload PDF (452K) -
KATSUHIRO SHIBATA, EIICHI OGAWA, KOICHI SAITO1955 Volume 2 Issue 1 Pages 23-32
Published: 1955
Released on J-STAGE: January 25, 2011
JOURNAL FREE ACCESSUsing the intact male and female adult rats of the Wistar strain, effect ofthyrotropin upon the uptake of I131 by he thyroid gland was investigated with special reference to the morphological changes of the thyroid in parallel to timeresponse. The uptake reached its maximum at the end of 4 hours after injection of thyrotropin, and then decreased with the lapse of time, returning to the normal value after 24 hours.Secretory function was indicated being most activated at 4 hours from morphological point of view.At 18 to 24 hours, the follicular cells were shown evidently swollen and proliferated, but secretory granules, secretory vacuoles and peripheral vacuoles were almost disappeared indicating secretory inactive phase of the glandular elements.Secretory process was cytologically discussed in some detail.View full abstractDownload PDF (5871K) -
MASASHI ENAMI1955 Volume 2 Issue 1 Pages 33-40
Published: 1955
Released on J-STAGE: January 25, 2011
JOURNAL FREE ACCESSIn addition to the cytoplasmic secretory activity in the cells of the preoptic nucleus of the eel, Anguilla japonica, which is responsible for the production of the so-called Gomori-positive neurosecretory material, a characteristic secretory activity is disclosed with the nuclei of the cells in question. Various aspects of nuclear transformation are observed, which are regarded to be concerned with the elaboration of a kind of acidophil, Gomori-negative, secretory material. The secretory material is conceded to be produced as the result of a kind of pyknotic change of the cell nucleus, and partially extruded into the blood capillaries without being subjected to further transformation within the cytoplasm. The modified ncleus presumably restores its integrity through a process of differentiation of basophil elements from the remainder of the acidophil material. Such nuclear change is not associated with any visible sign of cellular degeneration, and are considered to be of characteristic features in physiologically normal animal.View full abstractDownload PDF (7111K) -
KATSUTOSHI IMAI1955 Volume 2 Issue 1 Pages 41-46
Published: 1955
Released on J-STAGE: January 25, 2011
JOURNAL FREE ACCESSAs regards the secretory activity of the cells of the preoptic nucleus in the toad, Bufo vulgaris formosus BOULENGER, two separate modes of cytoplasmicsecretion are distinguishable, which are responsible for production of different kinds of secretory material respectively. One of the secretory behaviors is concerned with elaboration of fine granules with predominant affinity to anilin blue component of Mallory's triple stain, which apparently represents the product of neurosecretion widely known with the hypothalamic nuclei in various groups of vertebrates. In addition to such secretory material, another kind of colloid material in the form of large or small spherules takes its origin in the cytoplasm of the neurosecretory cells in question, which stains pronouncedly with either acid fuchsin or Orange G in Mallory's staining and is expelled directly to the extracellular space. Alternative staining of the same sections consecutively with Mallory's stain, Heidenhain's iron hematoxylin and Gomori's chrome alum hematoxylin has demonstrated that the materials in question are decicedly distinguishable from each other in that only the spherule colloid stains with iron hematoxylin.View full abstractDownload PDF (1731K) -
KISHUO SHIBUSAWA, SUMIO SAITO, MIEKO FUKUDA, TADAKAZU KAWAI, FUJIO YOS ...1955 Volume 2 Issue 1 Pages 47-56
Published: 1955
Released on J-STAGE: January 25, 2011
JOURNAL FREE ACCESS1) Adult mongrel dogs, albino male rats, and human subjects were employed test the effect of Vasopressin and Oxytocin on the adenohypophysis. The experiments were carried out in three groups: Pitressin-injected, Pitocin-injected, and human urine Extract-injected groups.
2) By the injection of Pitressin, the pituitary-adrenocortical system is stimulated and the secretion of ACTH increases.
3) After the administration of human urine Extract, possessing a striking antidiuretic activity, similar changes as by the Pitressin injection occurs in the function of the pituitary-adrenocortical system.
4) Pitocin seems to increase the secretion of the gonadotrophic hormone, judged by the fractionations of urinary 17-ketosteroids and histological findings of adenohypophysis.
5) Brief discussions have been made on the concept that the anterior pituitary stimulated by the hypothalamic-pituitary neurosecretion.View full abstractDownload PDF (8401K) -
YUHSUKE SUGISAWA1955 Volume 2 Issue 1 Pages 57-64
Published: 1955
Released on J-STAGE: January 25, 2011
JOURNAL FREE ACCESS1. An improvement was made with Thunberg technique so as to follow the rate of methylene blue reduction more accurately by means of colorimetric observation.
2. With the use of the technique, effect of thyroxine upon succinic dehydrogenase activity in mouse liver homogenate was observed in wide range of the hormone concentration.
3. Thyroxine was learned to be dually effective in the sense that comparatively lower concentrations around 7×10-7M are always acceleratory and higher concentrations above 1.4×10-6M are inhibitory.
4. On the basis of the present data, the mechanism of dual effect of thyroxine as observed with succinic oxidase system as a whole and oxygen consumption of tissue preparations was discussed.View full abstractDownload PDF (549K) -
HIROO TAKIKAWA1955 Volume 2 Issue 1 Pages 65-78
Published: 1955
Released on J-STAGE: January 25, 2011
JOURNAL FREE ACCESS1. Thyroxine shows in alkaline solution (pH12.30) ultraviolet absorption maximum at 227mμ. and 327mμ. The linear relationship between the concentration and absorbance was found in the limited concentration range.
2. The polarogram of thyroxine in ammoniumhydroxide and ammoniumchloride adding hcxamethonium bromide solution shows three waves having halfwave potentials of about-0.8, -1.0 and 1.2v. The height of the second wave found to be proportional to the ammount of thyroxine in the limited concentration range.
3. The ammount of thyroxine in the presence of 3, 5-diiodotyrosine was determined by means of polarographic analysis.
4. Free iodines in thyroxine solution were determined in potassium nitrate electrolyte at the half-wave potential of-0.03v.
5. It is proved that thyroxine is decomposed by ultraviolet irradiation in alkaline solution.View full abstractDownload PDF (977K) -
TOSHIO TORII, SATOSHI SASAKI, SEIJI MURANAKA, TAKESHI MORINAGA, SHOJIR ...1955 Volume 2 Issue 1 Pages 79-86
Published: 1955
Released on J-STAGE: January 25, 2011
JOURNAL FREE ACCESS24-hour periodicity in circulating eosinophils and urinary excretion of 17-ketosteroids and total 17-hydroxycorticoids in normal subjects were studied.
1) The maximal level of circulating eosinophils was observed at midnight and minimal one at noon.
2) The maximal excretion of urinary 17-ketosteroids wa s observed during the morning hour (06: 00-09: 00) and minimal one at the time period just before awakening (03: 00-06: 00).
3) The feature of the rhythm of urinary total 17-hydroxycorticoids was similar to that of 17-ketosteroids.The maximal value was observed at the same time as 17-ketosterids (06: 00-09: 00), but minimal one at midnight (00: 00-03: 00).
4) The correlation coefficient between relative value of circulating eosinphils and that of 17-ketosteroids or 17-hydroxycorticoids are -0.343 and -0.307 respectively. These figures are not large, but statistically significant below 1% level.View full abstractDownload PDF (516K) -
AMENDMENT ON THE ESTIMATION OF TOTAL 17-HYDROXYCORTICOIDS IN URINE USING SEMICARBAZIDE HYDROCHLORIDETOKUJI ICHIKAWA, MASAYOSHI WAKU, MAKOTO ISHIMOTO1955 Volume 2 Issue 1 Pages 87-88
Published: 1955
Released on J-STAGE: January 25, 2011
JOURNAL FREE ACCESSDownload PDF (136K)
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