Endocrinologia Japonica
Online ISSN : 2185-6370
Print ISSN : 0013-7219
ISSN-L : 0013-7219
Volume 4, Issue 4
Displaying 1-9 of 9 articles from this issue
  • SOTOJI OTSUKA
    1957 Volume 4 Issue 4 Pages 219-226
    Published: 1957
    Released on J-STAGE: January 25, 2011
    JOURNAL FREE ACCESS
    The two per cent sodium chloride and 40 per cent ethanol extracts of domestic fowl pituitaries accelerate the growth of ovarian follicles in immature female mice. The precipitate of fowl pituitaries at the step of the 0.5 or 0.8 saturated ammonium sulphate solution had also a similar effect on immature female mice. Both the follicle stimulating and the luteinizing substances similar to those of mammals are extracted by the rivanol method from domestic fowl pituitaries. The follicle stimulating and the luteinizing substances of frog pituitaries are extracted with 40 per cent ethanol. The follicle stimulating substance of frog pituitaries is extracted by rivanol method.
    The residue of frog pituitaries at the step of 40 per cent ethanol extraction was very injurious on immature female mice.
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  • MASUO TOBE
    1957 Volume 4 Issue 4 Pages 227-235
    Published: 1957
    Released on J-STAGE: January 25, 2011
    JOURNAL FREE ACCESS
    Changes in blood sugar value elicited by intravenous administration of glucose were investigated with 60 normal rats. Forty five of the obtained curves (75%) belonged to the so-called atypical curve type.
    Following adrenalectomy, the diversity in the curve type which was characteristic of the normal animal disappeared and the curves showed the exponential type with only slight fluctuations from one individual to another.
    Administration of hydrocortisone acetate in a daily dose of 2.5mg for 2 days after adrenalectomy returned the glucose tolerance curve to the pre-operative one.
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  • KIYOSHI YAMAMOTO, YUHSUKE SUGISAWA
    1957 Volume 4 Issue 4 Pages 236-247
    Published: 1957
    Released on J-STAGE: January 25, 2011
    JOURNAL FREE ACCESS
    The action of thyroxine upon succinic dehydrogenase system of mouse heart and liver homogenates was studied in a variety of experimental conditions, employing Thunberg technique. For the purpose of the present work, a practically reliable index for the activity of succinic dehydrogenase was devised. Experimental results have shown that the action of thyroxine was of an extremely complicated nature depending upon the amounts of thyroxine, homogenate and succinate, as summarized in Table 7. Some considerations were made based on the present results.
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  • KINORI KOSAKA, TAKEHIKO IDE, NOBUSADA KUZUYA
    1957 Volume 4 Issue 4 Pages 248-252
    Published: 1957
    Released on J-STAGE: January 25, 2011
    JOURNAL FREE ACCESS
    A method using hypophysectomized-adrenodemedullated rats for the assay of small quantities of insulin is described.
    If known quantities of insulin are added to plasma kept at room temperature overnight, they produce quantitatively similar effects on the rat as in the absence of plasma. The method allows determination of alteration in the insulin concentration of plasma.
    The insulin concentration in peripheral blood plasma of fasting human subjects and dogs is lower than the minimal quantities of insulin which could be estimated by the present method.
    The insulin concentrations in peripheral human plasma 90 to 120 minutes after meal are 0.2 to 0.3 milliunit per ml, and in normal dogs after intravenous injection of 20 g of glucose are 0.3 to 0.4 milliunit per ml.
    The insulin concentrations in blood obtained from the superior pancreaticoduodenal vein in fasting dogs are 0.2 to 0.3 milliunit per ml, and in the blood from the pancreatic branch of splenic vein are 0.3 to 0.4 milliunit per ml.
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  • KOICHI SAITO, KATSUHIRO SHIBATA
    1957 Volume 4 Issue 4 Pages 253-261
    Published: 1957
    Released on J-STAGE: January 25, 2011
    JOURNAL FREE ACCESS
    Experiments were carried out on the parafollicular cells (PC) in the rat thyroid, with the following results.
    These are independent cells which develop from follicular epithelium at 3 weeks of age, increasing with age. They can be divided into the clear and granular cells, and the transformation from one type to the other is noted. PC are independent from the changes produced in follicular epithelium by the administration of TSH, methylthiouracil or thyroxine.
    PC are visible at long time after the hypophysectomy, becoming rather more distinct with the lapse of time. Any observable change was not induced by the administration of autnomic drugs nor by exposure to high or low temperature. PC did not take trypan blue in an attempt of vital staining.
    From these results PC are considered to participate in the production of new follicles.
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  • KIYOSHI YAMAMOTO, MITSUO SUZUKI
    1957 Volume 4 Issue 4 Pages 262-267
    Published: 1957
    Released on J-STAGE: January 25, 2011
    JOURNAL FREE ACCESS
    Succinic and glutamic dehydrogenase activities were measured on tissues of three species of tadpoles during the course of the metamorphosis, Glutamic dehydrogenase of the tail muscle of Rana catesbiana and succinic as well as glutamic dehydrogenase of the whole tail tissue of Rana japonica decreased prior to the beginning of the resorption of the tail, With eviscerated whole body of the Bufovulgaris formosus, the decrease in these enzymes took place at a similar stage followed by no marked change in proteolytic enzyme activity.
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  • KENTARO HIMENO, YUICHI TANABE
    1957 Volume 4 Issue 4 Pages 268-272
    Published: 1957
    Released on J-STAGE: January 25, 2011
    JOURNAL FREE ACCESS
    The administration of 0.3% of Enheptin (2-Amino, 5-Nitrothiazole) in the diet to the laying hens in each period of February and May June soon suppressed egg lay, but the drug had no effect on the release rate of I131 as thyroid hormone thyroid.
    Molting occurred only in Enheptin-fed hens which completed the preeding molt six months or more before.
    These results indicate that Enheption had no direct effect on the activation of feather papillae to induce molting, and it is concluded that natural molting in the hen is induced by the decrease in the ovarian activity, together with the senile deterioration of the structure in the feather follicle maintaing the old feathers after about six months from the preceding molting.
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  • MINORU NAKANO
    1957 Volume 4 Issue 4 Pages 273-279
    Published: 1957
    Released on J-STAGE: January 25, 2011
    JOURNAL FREE ACCESS
    I131 labclled monoiodotyrosine of high specific activity was incubated with the slices and the homogenates prepared from liver, kidney and thyroid of rats. Metabolic products of monoiodotyrosine was analized by using of paperchromatography.
    Liver and kidney slices well metabolized monoiodotyrosine and behaved to convert monoiodotyrosine into inorganic iodide and three unknown compounds. The ratio of radioactivity of these metabolic products to the total radioactivity had various alteration under the presence of arsenite or dinitrophenol.
    Liver and kidney homogenates slightly metabolized monoiodotyrosine. A sort of metabolic products in homogenates was similar to that in slices and these radioactivity increased in the presence of a-ketoglutarate.
    Thyroid slices metabolized monoiodotyrosine and converted monoiodotyrosine only into inorganic iodide.
    Muscle slices never metabolized monoiodotyrosine.
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  • MITSUO SUZUKI, KINZO HASEGAWA
    1957 Volume 4 Issue 4 Pages 280-281
    Published: 1957
    Released on J-STAGE: January 25, 2011
    JOURNAL FREE ACCESS
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