Attempt was made to analyze the circulatory dynamics in experimental anaphylaxis in order to apply these results to emergency therapy. Interrelation between shock phenomenon and allergic reaction was discussed.

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The cerebral circulatory function and metabolism in juvenile hypertension were studied in the use of nitrous oxide technique. The remarkably increased CBF and CMRO₂ and the unchanged CVR in young hypertensive patients were observed when compared with the values of the young normotensive subjects and the hypertensive patients in middle aged and old aged. The mechanism of these findings in cerebral hemodynamics and metabolism were discussed. Some correlations between elevating blood pressure and increasing CBF, CVR and CMRO₂ were observed. The renal function was compared with the cerebral circulatory function in essential hypertension. A considerably increased RPF in young hypertensive patients and a definite correlation between CBF and RPF in hypertensive patients were observed.

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It is now generally accepted that lipemia has a close relationship to the pathogenesis of arteriosclerosis, and blood coagulation has been reported to be accelerated by alimentary lipemia. Recently the atherogenic factor of lipemia has been discussed with reference to this hypercoagulability induced by lipemia. This paper presented the experimental investigations on the influence of hypercoagulability in the pathogenesis of the arteriosclerosis. Authors found that blood coagulability was markedly accelerated in vivo after the injection of celite, which was demonstrated in the decrease of whole blood clotting time, the increase of serum thromboplastic factor and the decrease of some blood clotting factors which were asssumed to be due to the increased consumption of them in vivo. The atherosclerotic changes in aorta and pulmonary arteries produced with cholesterol feeding were accelerated by this experimentally induced hypercoagulability. From these results authors considered that hypercoagulability of blood probably plays the primary role in the pathogenesis of arteriosclerosis.

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