The experiment with rabbits was to show whether CHCl
3 and C
2H
5OH were effective or not as the secondary or booster exposure of detecting inapparent industrial poisoning of CCl
4. Results were as follows. (1) There appeared no change at all in plasma GPT activities when CHCl
3 at 0.1cc/kg was administered to the normal rabbits. And after repeated administrations of a small dose of CCl
4 for 5 weeks, there was no change in GPT activities either. Receiving booster injection of a single dose of CHCl
3 at 0.1cc/kg the animals reacted to the dose by an apparent increase of plasma GPT activities this time. This result implies that CHCl
3 was effective as a secondary or booster exposure to detect the inapparent poisoning of CCl
4. (2) There was no change in plasma GPT activities when 50% C
2H
5OH at 10 cc/kg was subcutaneously injected to the chronically CCl
4 poisoned rabbits. This result meant that C
2H
5OH was not effective as a secondary or booster exposure to detect the inapparent poisoning of CCl
4. (3) The authors discussed that CCl
4 and CHCl
3 were effective as the secondary or booster exposure to detect the inapparent poisoning of CCl
4, and that the action of CCl
4 and CHCl
3 upon the inapparently poisoned animals had not yet been confirmed.
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