Although there are many reports on the relationship between individual unhealthy lifestyle habits and life-stylerelated diseases, few reports have focused on the relationship between the number of unhealthy lifestyle habits andlifestyle-related diseases. Therefore, we investigated whether the number of unhealthy lifestyle habits affects thenew onset of lifestyle-related diseases. Participants were selected based on whether they had undergone the medical examinations in both 2014 and 2019, and whether they had answered all five unhealthy life style questions in2014, and whether they had all tests for life style-related diseases in 2014 and 2019. A total of 1,827 people wereanalyzed. The results of the multiple logistic regression analysis revealed that the number of unhealthy lifestylehabits were a significant risk factor for new-onset diabetes (p = 0.005, adjusted odds ratio: 2.71, 95% confidenceinterval: 1.19–6.18) and hypertension (p = 0.003, adjusted odds ratio: 2.59, 95% confidence interval: 1.50–4.45).Furthermore, the number of unhealthy lifestyle habits was associated with a significant risk for new-onset diabetes and hypertension among men and aged 40–59 years. Multiple unhealthy lifestyle habits at the same time posea risk of new onset of lifestyle-related diseases, so it is important to provide health guidance with a focus on thenumber of unhealthy lifestyle habits that people have. In particular, this approach was considered to be more effective for men and patients aged between 40 and 59 years, for whom stratified analysis also revealed significantresults. Furthermore, even if a lack of sleep rest is considered an unhealthy lifestyle, a significant relationship wasfound between the number of unhealthy lifestyle habits and new onset of lifestyle-related diseases. Therefore, it isconsidered reasonable to take measures by focusing on sleep quality when implementing health guidance.
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