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Volume 29, Issue 2
Displaying 1-5 of 5 articles from this issue
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TOSHIHIKO ARAI, TAKAO ANDO1980 Volume 29 Issue 2 Pages 47-54
Published: 1980
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSSome of the naturally occurring Iα, Iξ, M, N, O and T group plasmids increase both the mutability and UV resistance of their host bacteria, while group H and S plasmids only increase mutability. This suggests that these two plasmid-mediated repair functions are separable. The two functions have no direct relation to their restriction-modification systems and nitrofuran resistant functions. In addition, the close linking between the restriction-modification genes and these repair function genes was suggested in group N plasmids.View full abstractDownload PDF (351K) -
TAKAO ANDO, TOSHIHIKO ARAI1980 Volume 29 Issue 2 Pages 55-66
Published: 1980
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSThe mechanisms of plasmid-mediated enhancement of UV resistance (U function) and mutability (M function) had been studied. Isolation of inde-pendent mutants for each of these two functions clearly indicated that they were controlled by different genes. It was suggested that genes for these two functions were different from the gene for the plasmid-mediated DNA poly-merase described by MacPhee. We also proved that the function to enhance UV resistance was related to nicking activity of damaged DNA.View full abstractDownload PDF (528K) -
MICHIYA NATORI1980 Volume 29 Issue 2 Pages 67-79
Published: 1980
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSA small ultrasonic transducer was designed and inserted into the uterus and the relation between the velocity of placental blood flow (PBF) and amniotic pressure was studied. The mean ± SD of amniotic pressure at sudden decrease of the velocity of PBF, was 42.2 ± 8.8mmHg and at recovery of the velocity of PBF, was 35.7 ± 7.4mmHg. This interval was discussed as the “loading interval” to the fetus.
For applying transcutaneous oxygen (tcPO2) electrodes to fetal monitoring, a fixing device to the fetal head was manufactured. Amniotic pressure and fetal tcPO2 were simultaneously recorded. FHR pattern was classified as no deceleration (ND), early deceleration (ED), late deceleration (LD), and variable deceleration (VD) according to the deceleration pattern, and fetal tcPO2 values were compared. LD and VD patterns showed a more hypoxic condition of fetus than did ND and ED patterns. From the relation-ship between the “loading interval” and the tcPO2 change, it was suggested that an amniotic pressure interval shorter than two minutes might cause hypoxia and at least a four-minute interval of amniotic pressure elevation should be controlled if fetal hypoxia is suggested.View full abstractDownload PDF (2390K) -
TOSHIHIKO ARAI1980 Volume 29 Issue 2 Pages 81-90
Published: 1980
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSSusceptibility of Treponema hyodysenteriae to various antibiotics and metabolic inhibitors was examined in comparison to those of various bacteria and fungi. As for susceptibility to DNA synthesis inhibitors, this treponema was sensitive not to furazolidone but to ethidium bromide and chloroquine. This treponema was resistant to rifampicin and actionmycin D; RNA synthesis inhibitors but sensitive to most of the protein synthesis inhibitors for procaryotes and inhibitors for oxidative phosphorylaton and electron transport systems, such as gramicidine S, azid and antimycin. This treponema was also a little resistant to colistin and ampicillin but very sensitive to clotrimazole. These results suggested that this organism have procaryotic ribosome system but eucaryotic membrane and electron transport systems. Therefore, we could use this organism as an agar plate-culturable indicator strain of eucaryotic membrane system to test the cytotoxicity of the newly developed antibacterial and other drugs.View full abstractDownload PDF (467K) -
KOHDOH ISHII, OSAMU SUZUKI, KATSUYA MARUYAMA, HIROSHI NAGATA, YASUO FU ...1980 Volume 29 Issue 2 Pages 91-98
Published: 1980
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSEffects of reduced glutathione (GSH) were evaluated in animals sub-jected to hemorrhagic shock. In this study using rabbits, three phases were shown in the pattern of bleeding, i.e., bleeding phase, quiescent phase and reflux phase with resultant animals' death. We observed marked disturbance in the levels of histamine during the course of hemorrhage. Administration of GSH abolished reflux phase, indicating well maintained vascular tone, and an exaggerated release of plasma histamine was significantly suppressed. In rats, microcirculatory disorders as well as the degranulation rate of mast cells in the mesentery were significantly prevented by the administration of GSH. Thus GSH seems to exert salutary effects on hemorrhagic shock primarily by the maintenance of vascular tone and suppression of the release of chemical mediators.View full abstractDownload PDF (331K)
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