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Volume 23, Issue 1
Displaying 1-4 of 4 articles from this issue
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TAKIKO KENJO1974 Volume 23 Issue 1 Pages 1-15
Published: 1974
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSIt has been recognized that macrophage migration inhibition test (MIT) would duly reflect various phases of cellular immunity in vitro, including delayed hypersensitivity, transplantation and anti-tumor immunity. The studies of cell-mediated immunity have been undertaken in vitro by the MIT on 73 patients with operable gynecologic tumor and on 10 mice bearing uterine tumor induced by 20-methylcholanthrene.
Eighty-six per cent of 29 patients with malignant tumors-choriocarcinoma, ovarian cancer and carcinoma of the uterine cervix and corpus-revealed positive migration inhibitory activity immediately after extirpation of pathology. On the contrary, all of the cases with benign tumor revealed negative reaction.
Out of 16 positive patients who were able to be followed, 12 cases received complete removal of pathology and disclosed negative reaction 35 to 60 days after the initial test. The reaction of four patients with wide-spread metastasis remained positive for more than 3 months after surgery.
Besides, the migration inhibitory activity were detected in only one out of 5 cases with invasive mole and 11 out of 33 patients with hydatidiform mole.
In addition, the positive reaction on MIT was presented in 90% of the mice bearing uterine tumor and cross reaction was also observed in some cases.View full abstractDownload PDF (811K) -
TOKIO FUJIMAKI, TETSUYA NAGASE, SHINJI SUZUKI1974 Volume 23 Issue 1 Pages 17-27
Published: 1974
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSThe cases of 1510 lumbar vertebral columns were investigated to know the interrelation between the grades of spur (osteophyte) formation and the age of patients by using a new method. Each spur was classified in five categories according to their severities, and given grading number of one to five. All the numbers were then summed up individually. By this method, difference by sex, difference between patients with and without radiological findings, and difference according their localisation were evaluated.View full abstractDownload PDF (2350K) -
CHENG-YI LEE, TAI AKERA1974 Volume 23 Issue 1 Pages 29-46
Published: 1974
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSDespite long and extensive efforts, biochemical basis for the narcotic tolerance and physical dependence is still unknown. It appears, however, that the development of tolerance to, and physical dependence on, narcotics is related to protein synthesis mechanisms in the central nervous system, which results in alterations in either neuro-transmitter mechanism(s) or receptor protein or both. Recent advances in studies on protein synthesis and the successful demonstration of “opiate receptor” may shed light on the biochemical nature of these intriguing phenomena.View full abstractDownload PDF (1234K) -
TOYOMI FUJINO, TAKAO HARASHINA, RYUZABURO TANINO, TOSHIO OHSHIRO, FUMI ...1974 Volume 23 Issue 1 Pages 47-52
Published: 1974
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSTwo cases of clinical success of distant transfer of free skin flap in head and face regions by microsurgical anastomoses are reported. Case 1 is a 31 year old male with cicatricial, alopecia of the scalp and treated by a free hairy scalp transfer. Case 2 is a 20 year old male with burn contracture of the chin and cheeks with ectropion of the lower lip and treated by a free deltopectral skin flap transfer.View full abstractDownload PDF (2928K)
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