All issues
Volume 23, Issue 4
Displaying 1-4 of 4 articles from this issue
- |<
- <
- 1
- >
- >|
-
KENICHIRO IWAMURA, HIROYUKI NISHIKAWA, TATSUNOSUKE KAWAMURA, KOHZABURO ...1974 Volume 23 Issue 4 Pages 165-176
Published: 1974
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSIn these three years, the authors performed the endoscopic retrograde pancreatocholangiography in 135 patients with diseases of the bile duct, the gallbladder and the pancreas. At the beginning of introduction of the retrograde pancreatocholangiography in our clinic, we have not always succeeded in this diagnostic procedure. Up to now, the duodenofiberscopic retrograde pancreatocholangiography made the diseases of the bile duct, the gallbladder and the pancreas clear in 71 of 135 patients: that is to say, in 39 patients, the diseases of the bile duct and the gallbladder, as well as in 32, the diseases of the pancreas. Nowadays, we can succeed in this diagnostic procedure in more than 80% of cases.
Based on these findings, it can be said that the endoscopic retrograde pancreatocholangiography will be capable of being an effective diagnostic tool. It leaves, however, some room for consideration concerning the interpretation of the obtained figures.View full abstractDownload PDF (6393K) -
MASAAKI NAKAZONO, KUNIYOSHI TAJIMA, YUKIHIKO NOSE1974 Volume 23 Issue 4 Pages 177-190
Published: 1974
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSGordon et al has reported that one to two liters of dialysate with chemical adsorbents has the capability of carrying out effective hemodialysis, and ever since isolated intestinal loop dialysis has been performed clinically by several investigators.
These reports suggest that the isolated gastrointestinal tract can be used as a container for dialysate with chemical adsorbents to carry out dialysis for 24 hours a day without the necessity of frequent exchange of dialysate and the patient be free from any lines or attached equipment.
It is also possible that this procedure could be supplemented with hemo dialysis either with conventional equipment or a compact hemodialyzer inserted into isolated gastrointestinal tract or stomach pouch, jejunal loop and colon loop. The capability of these three types of isolated gastrointestinal loop were studied and reported.
It was found that isolated jejunal loop primed with dialysate containing chemical adsorbents such as activated charcoal for removal of creatinine and other organic metabolites and Kayexalate, a cation exchange resin for removal of potassium, can serve as a life saving method for uremic dogs. However, some methods to allow the circulation of dialysate throughout the loop and avoid the accumulation of charcoal and chemical resin at the end of the loop must be improved.
Studies on insertion of compact hemodialyzers into the isolated gastro intestinal loop will be discussed elsewhere.View full abstractDownload PDF (623K) -
KOJI FUKUSHIMA, SOGEN ITOH, SHIGESHI TOYOSHIMA1974 Volume 23 Issue 4 Pages 191-204
Published: 1974
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSToxicity of five antitumor amino acid derivatives, N-β-naphthalenesulfonyl-DL-tryptophan(A-91), β-naphthylaminomethyl-γ-aminobutyric acid (A-144), N-ethylcarbaminomethyl-L-isoleucine(A-145), N-9-fluorenylacetyl-Lphenylalanine(A-192), and N-propionyl-L-valine(A-195) were studied in mice and rats. These amino acid derivatives (A-A derivatives), with the exception of A-192, were less toxic in mice and rats administered single intraperitoneally (ip) and orally(po).
In repeated-dose studies with the five A-A derivatives, the rats were treated ip with daily doses of one-third LD50 every day for 10 days. During the observation period, the rats treated with A-A derivatives, with the exception of A-195, showed no adverse signs and caused no body weight loss. However, some rats treated with A-195 developed poor apetite or anorexia, weight loss, and death during the two weeks observation period. Treatment of A-A derivatives caused no leukopenia, as in treatment of Mitomycin-C, and the other hematologic toxicity was slightly changed compared with the control groups.
Renal and hepatic functions were slightly affected in rats treated with A-A derivatives.
Severe lesions were noted in testes of rats treated with Mitomycin-C, but treatment with A-A derivatives caused moderate lesions in testes. All other tissues appeared to be normal.
These results indicate that the toxicity of A-A derivatives is less toxic than that of Mitomycin-C in animals.View full abstractDownload PDF (651K) -
NOBUO YOSHII, KINYA OSHIDA, SAKAE FUKUDA1974 Volume 23 Issue 4 Pages 205-210
Published: 1974
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSExamined the EEG evaluation results of 218 aged patients over 60 years old with head injuries, in order to explore the relationship between the EEG evaluation results and the period of unconsciousness, period from injuries to the EEG test, skeletal bone fracture, and remarkable clinical symptoms. As a result, it was found out that: 1) The older the age, the higher the frequency of abnormal EEG, 2) The longer the period of unconsciousness, the higher the frequency of abnormal EEG, while the longer the period of unconsciousness, the longer the period of abnormal EEG after injuries, 3) Those with skull fracture and/or remarkable clinical symptoms indicated higher frequency of abnormal EEG. Brains of aged people are prone to indicate highly notable changes once external forces are applied to them, and this is attributed to the changes usually taking place as the age advances, unlike the changes indicated by the immature brains of infants. Hence, clinical application of EEG should by done with consideration paid in connection with precise clinical examinations. It should be emphasized that enough care should be taken in its evaluation by performing repeated EEG tests with some intervals.View full abstractDownload PDF (319K)
- |<
- <
- 1
- >
- >|