The Keio Journal of Medicine
Online ISSN : 1880-1293
Print ISSN : 0022-9717
ISSN-L : 0022-9717
Volume 55, Issue 1
Displaying 1-4 of 4 articles from this issue
ORIGINAL ARTICLES
  • Akiko Kimura, Tomohisa Nagasao, Tsuyoshi Kaneko, Junpei Miyamoto, Tats ...
    2006 Volume 55 Issue 1 Pages 1-8
    Published: 2006
    Released on J-STAGE: July 07, 2006
    JOURNAL FREE ACCESS
    The purpose of this study is to determine the most stable fixation method for mandibular symphysis fractures by comparing the mechanical characteristics of models fixed at different positions with different numbers of plates. Fractures were generated in 3-dimensional finite element models, and were fixed with a single miniplate, parallel double miniplates, or perpendicular double miniplates. A 300 N perpendicular load was then applied on the left molar region, and a finite element analysis was performed. We compared vertical gaps between the fractured surfaces, maximum stress within the screw/plating system, and maximum stress around screw holes in the bone. Compared to the single miniplate, both the parallel and perpendicular double miniplates demonstrated significantly less stress in the screw/plating system and screw holes in the bone. In addition, the perpendicular double miniplates had significantly smaller vertical gaps between fracture surfaces when compared to the single miniplate. Comparing parallel and perpendicular double miniplate fixations, less stress was found around the screw holes of the perpendicular miniplate models than those of the parallel miniplate models. There were no differences in vertical gaps or maximum stress within the screw/plating systems between the 2 double miniplate fixations. These results suggest that perpendicular double miniplate fixation is more suitable for fixing mandibular symphysis fractures.
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  • Christy LM Hui, Eric YH Chen, CS Kan, KC Yip, CW Law, Cindy PY Chiu
    2006 Volume 55 Issue 1 Pages 9-14
    Published: 2006
    Released on J-STAGE: July 07, 2006
    JOURNAL FREE ACCESS
    Objective: Adherence to antipsychotic treatment is an important aspect of long term management of schizophrenia and other related psychotic disorders. The evaluation of adherence is often difficult in clinical settings. This study compared patients self-reports and clinician judgment of adherence behavior and explored their relationship with attitudes toward taking medication. Methods: Clinician rated questionnaire and matching patient self rated questionnaires were administered to 508 consecutive outpatients and their clinicians in four hospital clinic sites in Hong Kong. Items in the questionnaires address adherence behaviors as well as attitudes toward medication. In addition, clinicians also estimate the presence of factors unfavorable to adherence such as substance abuse, cognitive impairments etc. Results: Non-adherence was reported in at least 26% of patients. Clinician’s detection of non-adherence behaviors achieved relative high specificity (0.84) but has low sensitivity (0.33). A logistic regression analysis on patients’ decision to stop medication revealed that significant predictors include patients’ reported lack of perception from the benefits of medication, patients’ reported negative feelings associated with regular medication and younger age. Conclusion: Non-adherence is a widespread phenomenon affecting a significant proportion of outpatients under treatment. Clinicians have relatively low sensitivity in detecting which patients are non-adherent. Non-adherence behavior is predicted by level of awareness of illness, perceived benefits of medication, negative feelings toward medication and age.
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  • Shunya Ikeda, Mia Kobayashi
    2006 Volume 55 Issue 1 Pages 15-22
    Published: 2006
    Released on J-STAGE: July 07, 2006
    JOURNAL FREE ACCESS
    Stenting with a sirolimus-eluting stent (SES) dramatically reduces the risk of restenosis compared to bare metal stent (BMS) implantation. However, before SES can be widely adopted in clinical practice, it is essential to conduct an economic evaluation of this effective but expensive device. Our study was undertaken to estimate the three-year cumulative medical costs of stenting using SES compared to BMS. The data on clinical sequelae of stenting using BMS were derived from our previous study, based on data collected from three Japanese hospitals. We estimated that the probability of PTCA required for revascularization would be 0.224 times in SES implantation compared than in BMS implantation based on the SIRIUS study result. The medical costs for procedures were obtained from published articles and were adjusted to the March 2005 level. Our simulation showed the expected three-year cumulative medical cost per patient to be approximately \\200,000 lower in the SES group (\\2,233,000) than in the BMS group (\\2,431,000). Sensitivity analyses with different presumptions confirmed that the economic advantage of SES over BMS was quite robust. We concluded that the use of SES would be a cost-saving option as compared with BMS implantation within the context of the Japanese healthcare system.
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CASE REPORT
  • H.-J. Hartmann, A. Steup
    2006 Volume 55 Issue 1 Pages 23-28
    Published: 2006
    Released on J-STAGE: July 07, 2006
    JOURNAL FREE ACCESS
    Various options are available for restoring anterior teeth. Their choice is dictated by the severity of infection of the teeth to be extracted and the pocket depth. Immediate single-stage implant placement proved to be the least traumatic option, which best preserved the soft tissue. A differential use of surgical and prosthodontic techniques is indispensable to account for conditions in the individual case. Given an adequate amount of hard tissue, soft tissue contours can be expected to return to normal. Immediate implants combined with a soft tissue support have been found to ensure that the depth of even larger pockets is stable for years.
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