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Volume 33, Issue 2
Displaying 1-3 of 3 articles from this issue
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HIDEO NAKAJIMA, TOYOMI FUJINO1984 Volume 33 Issue 2 Pages 59-82
Published: 1984
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSSeveral new island fasciocutaneous flaps have been reported. They depend on new concept of the vascular supply to the skin. This concept different from one used up to the present will be applied hereafter.View full abstractDownload PDF (16659K) -
CHIKARA OSHIO1984 Volume 33 Issue 2 Pages 83-97
Published: 1984
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSThe behavior of platelets in capillary hemorrhage has been investigated by using highly purified hemorrhagic principle from a snake venom. The first capillary hemorrhage was observed through a light microscope four minutes after topical application of the hemorrhagic principle to the microcirculatory system of the rat mesentery. With time hemorrhagic spots increased in number and size. The electron microscopic observations of the affected capillaries showed a partial discontinuity of the endothelial lining. The basement membrane occasionally maintained its continuity even when the endothelial cells did not. When the endothelial gap was narrower than one micron, a single platelet which had not degranulated, was frequently seen to have a pseudopod within it. When the gap was 1-2 microns wide, platelets appeared to change their shape so as to fit the entire cell into the gap. Most of these platelets showed partial degranulation. When the gap was more than two microns wide, platelets collected and degranulated into it. In general, the wider the endothelial gap was, the more platelets collected and degranulated in it. Some degranulated platelets were found in the area enclosed by endothelial cells, a basement membrane and a pericyte. The experimental results suggest that the endothelial injury itself may provoke the reaction of platelets before the platelets make contact with extra-capillary tissue constituents.View full abstractDownload PDF (5363K) -
MASARU MORISADA1984 Volume 33 Issue 2 Pages 99-111
Published: 1984
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSIgG anti-A and anti-B were isolated from one patient who showed extremely high anti-A and anti-B antibody titers by the indirect antiglobulin test. These IgG were conjugated with horseradish peroxidase (HRP). A human term placenta of blood type B from a type-O mother was incubated in a solution containing these anti-A and anti-B IgG-HRP conjugates.
It is indicated that anti-A and anti-B IgG-HRP are endocytosed into the syncytiotrophoblast but these IgG-HRP lose it's character as immunoglobulin promptly after endocytosis from the results obtained, i.e., positive peroxidase reaction was widely observed inside the trophoblast but immunofluorescence carried out by use of rabbit anti-human IgG/FITC was positive only at the apical portion of the syncytiotrophoblast. On the contrary, in the control experiments used of the same placenta of the experiment and non-specific human IgG-HRP, it is verified that non-specific human IgG was transfered across the syncytiotrophoblast into the fetal side without changing its charactor as immunoglobulin.
These results might support our hypothesis published in 1976, under the title of “Immunobiological Function of the Syncytiotrophoblast: A New Theory”, 1 in which we explained how the fetus is prevented from circulating maternal IgG class antibodies aimed at fetal antigens, such as HLA and ABO, etc.View full abstractDownload PDF (3001K)
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