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Volume 21, Issue 3-4
Displaying 1-10 of 10 articles from this issue
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MASAHARU TSUCHIYA1972 Volume 21 Issue 3-4 Pages 127-145
Published: 1972
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSDownload PDF (3384K) -
SHIGERU ARIMORI, YASUNARI NAKATA1972 Volume 21 Issue 3-4 Pages 147-158
Published: 1972
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSIsolated rat muscle and human erythrocyte membranes as antigens have been disaggregated with sodium dodecyl sulfates (SDS).
A positive anti-membrane factor detected with l'électrosynérèse (Bussard) was demonstrated in 12.8% of the sera from myasthenia gravis patients and 100% of the systemic lupus erythematosus (SLE) patients. Various other dis-eases, such as collagen diseases, malignant tumours and chronic infections, had less than 50% positive precipitin reactions, and 200 healthy individuals were all negative. The membrane solution, after reducing the SDS to a concentration of less than 2±10-3 M, always gave a positive precipitin reaction against the sera of SLE patients. These finding suggest a new clinical entity of “Membrane Dis-ease.”View full abstractDownload PDF (3111K) -
KIMIYOSHI TSUJI, HIROSHI MIYAMOTO, MOTOAKI ITO1972 Volume 21 Issue 3-4 Pages 159-169
Published: 1972
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSHL-A and its clinical application in the following four subjects was discussed.
1) The correlation between HL-A typing and renal transplantation,
2) HL-A and susceptibility to gastric cancer,
3) Relation to the habitual abortion,
4) HL-A antigenic loss in a cancer patient.View full abstractDownload PDF (510K) -
A STUDY ON 124 BEAGLESRIKIO NIKI, YOSHIO TAKAGAKI, MASANOBU FUKUI, SATOSHI TOMINAGA1972 Volume 21 Issue 3-4 Pages 171-179
Published: 1972
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSThyroiditis of unknown etiology occurred in 5 (7.6%) of the 65 males and 6 (10.1%) of the 59 females in purebred young and adult beagle dogs. There were no gross lesions or clinical signs of thyroid dysfunction. The microscopic lesions were characterized by nodular and diffuse infiltration of the thyroid gland by lymphocytes, plasma cells and a few macrophages and neutrophiles. It was suggested that the spontaneous thyroiditis in beagles may provide a very useful tool for studying human chronic thyroiditis.View full abstractDownload PDF (4157K) -
MORITO MARUTA, KEIICHI YOSHINO, TAKASHI MIMURA, HIROSHI YOSHIMATSU, MI ...1972 Volume 21 Issue 3-4 Pages 181-188
Published: 1972
Released on J-STAGE: March 27, 2009
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KASHU SHIMABUKURO, YOSHIO MIZUNO, MASAHARU TSUCHIYA1972 Volume 21 Issue 3-4 Pages 189-199
Published: 1972
Released on J-STAGE: March 27, 2009
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NORIKAZU TAMAOKI, SONOKO HABU, HIROSHI YOSHIMATSU, MASAHARU TSUCHIYA, ...1972 Volume 21 Issue 3-4 Pages 201-213
Published: 1972
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSHistologies of the thymuses resected from 22 cases of Behcet's disease were described. The incidence of thymic lymphoid follicle was 66% (6/9) in patients not treated with systemic steroid therapy, 80% (4/5) in those who discontinued steroids for more than three months before thymectomy, and 13% (1/8) in one who was treated at or within three months before the resection. Hyperplasia of spindle-shaped epithelial cells with the disappearance of Hassall's corpuscle was noted in five out of eight cases treated and in one case not treated with systemic steroid administration. It was suggested that the presence of thymic lymphoid follicles and spindle-shaped epithelial cells might be related to basic abnormalities in the pathogenesis of Behget's disease. Two cases associated with thyroid carcinoma and two cases with lymphoid thyroiditis were also reported.View full abstractDownload PDF (4094K) -
HIROSHI YOSHIMATSU, TSUNEO ISHIHARA, KEIICHI KIKUCHI, TAKAAKI IKEDA, S ...1972 Volume 21 Issue 3-4 Pages 215-233
Published: 1972
Released on J-STAGE: March 27, 2009
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KASHU SHIMABUKURO, KEIZO TAKAGI, YASUYOSHI KIRYU, MASAHARU TSUCHIYA, H ...1972 Volume 21 Issue 3-4 Pages 235-254
Published: 1972
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESS1) Blood factors in myasthenia gravis
In this disease, frequency of complication of other autoimmune diseases is high, and blood factors should be discussed with reference to this.
(1) Serum γ-globulin seldom gives high value in this disease alone.
(2) Regarding the abnormal pattern of serum immunoglobulin, increases and decreases in IgG appeared in equal frequency. For the other im-munoglobulins, IgA is low and IgM is high.
(3) Peripheral lymphocyte counts are low in many cases.
2) Fluctuations of blood factors in myasthenia gravis following thymectomy
(1) Immunoglobulin especially of IgG decreases significantly at an early period after thymectomy, followed by a gradual rise again. Long-term postoperative observation revealed a tendency towards normalization of IgG and IgA.
(2) Peripheral lymphocytes significantly decreased at an early postoperative period. Observation for a longer perid revealed a tendency towards normalization.
(3) As to the relationship between the therapeutic effects after thymectomy and fluctuations of the blood factors, symptoms improved after opera-tion in cases with postoperative early decrease of IgG and peripheral lymphocytes.
(4) In the relationship between the thymic tissue and blood factors, im-munoglobulin especially of IgG gave low values with little postopera-tive changes and having no lymph follicles formation within the thymus.View full abstractDownload PDF (11866K) -
HIROSHI NAKAMURA, HIROSHI YOSHIMATSU, MASAHARU TSUCHIYA, NORIKAZU TAMA ...1972 Volume 21 Issue 3-4 Pages 255-266
Published: 1972
Released on J-STAGE: March 27, 2009
JOURNAL FREE ACCESSThe course of 5 patients were studied after renal allotransplantation from related donors. Transcervical thymectomy was performed after transplantation in 2 patients and before transplantation fir the other 3 recipients.View full abstractDownload PDF (4300K)
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