Journal of the Mass Spectrometry Society of Japan
Online ISSN : 1880-4225
Print ISSN : 1340-8097
ISSN-L : 1340-8097
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Volume 70, Issue 1
Displaying 1-19 of 19 articles from this issue
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Preface
Special Issue: Molecular Science
Basic Lecture
Commentary
Topics
Instrument and Technology
  • Enantio-Separation by Ion-Mobility Spectrometry
    Eiji Sugiyama, Hajime Mizuno, Kenichiro Todoroki
    2022 Volume 70 Issue 1 Pages 74-76
    Published: March 01, 2022
    Released on J-STAGE: March 15, 2022
    DOIhttps://doi.org/10.5702/massspec.S22-14
    JOURNAL FREE ACCESS
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    Most of physiologically active substances are chiral, and their enantiomers exhibit different biological properties. Separation of such chiral molecules by ion mobility spectrometry (IMS) enables rapid analysis or detailed distribution analysis using mass spectrometry. In addition, recent progress in the resolution of IMS enables separation of various chiral molecules from their enantiomers. Here, we briefly introduce the methodology and our recent method to discriminate a target chiral molecule from its enantiomer by IMS.

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Letter to the Editor
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