Nihon Naika Gakkai Zasshi
Online ISSN : 1883-2083
Print ISSN : 0021-5384
ISSN-L : 0021-5384
Volume 45 , Issue 4
Showing 1-7 articles out of 7 articles from the selected issue
  • Yoshio Iwata, Koichi Murakoshi, Iwao Nakajima
    1956 Volume 45 Issue 4 Pages 325-334
    Published: July 10, 1956
    Released: February 22, 2011
    JOURNALS FREE ACCESS
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  • Yoshio Hayano
    1956 Volume 45 Issue 4 Pages 335-347
    Published: July 10, 1956
    Released: February 22, 2011
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  • Koichi Shinoda
    1956 Volume 45 Issue 4 Pages 348-356
    Published: July 10, 1956
    Released: February 22, 2011
    JOURNALS FREE ACCESS
    The following report is submitted on the paper electrophoretic data obtained by 117 cases of gastric juice in several diseases.
    (Method) The fresh gastric juice removed from an empty stomach in the morning was filtered by an aspirator, concentrated to 20:1 using the ultrafiltration method for 6 hours in the cold distilled water at negative pressure 240-300mmHg, and then electrophoreted. The protein was stained with Brom Phenol Blue (BPB), and mucoprotein was stained by Shiff's Periodic Acid Fuchsin Stain (PAS-reaction). Acid mucopolysaccharide was stained with Toluidine Blue solution at ph 2.5 and 7.0, and the characteristic “Metachromasia” was observed. Lipid was stained with Sudan IV.
    (Results) In the gastric juice from healthy subject I found 5-6 low bands. In cases of acute and chronic gastritis, the electrophoretic patterns were not much different from the gastric juice of healthy subject.
    Gastric cancer showed a significant characteristic pattern, different from gastric ulcer and others.
    On the electrophoretic pattern of mucoprotein components in the gastric juice, 5 to 7 separate fractions were observed. Moreover, by the Toluidine Blue stain, it was found that the mucoprotein fraction with the highest mobility was containing acid mucopolysaccharides. This fraction may correspond with the “Glandular Mucopotein” of Glass and Boyd.
    Only small amounts of lipids were found in the gastric juice with gastric cancer in 12 of the 16 cases, but in other diseases they could hardly be found.
    These observations may be useful to the clinical diagnosis.
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  • Masao Kuramochi
    1956 Volume 45 Issue 4 Pages 357-366
    Published: July 10, 1956
    Released: February 22, 2011
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    The author inuvestigated the time relation between enduring hunger and diet factors, and found it was at large controlled by nitrogen metabolism in organs.
    The period of hunger-endurance becomes the longest in rabbits of high protein diet, and the shortest in those on high fat diet.
    In the beginning of hunger non-protein nitrogen in the experimental animals varies as the diet differs, but it tends to increase in the end. The increase is more conspicuous in organs than in the blood.
    As to urinary nitrogen excretion and reduction of the insoluble protein in mormal saline solution, high-protein-diet creatures show the minimum, and those on high carbohydrate show the maximum.
    In the last stage of hunger amino acids in organs increase, but in the liver on high fat diet alone they decrease.
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  • Katsusaburo Ishihara
    1956 Volume 45 Issue 4 Pages 367-377
    Published: July 10, 1956
    Released: February 22, 2011
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    Es ist schon sichergestellt, dass durch Acetylcholin-Inhalation beim Asthmatiker ein Anfall Künstlich hervorgerufen wird. Aber bisher fehlt es an Forschungen über ihre Wirkungsstelle und-weise. Der Verfasser hat mit einem Verstäuber durch eine bronchoskopische Röhre Acetylcholinlösung in vollkommen symptomenfreien Zeiten einmal in die kleinen Bronchien (1cc 20% auf beide Lungen verteilt) und an anderen Tagen in den oberen Teil des Bronchialbaumes (in die Trachea 1cc 10%) appliziert und gefunden, dass beim ersten Falle 11% (von 15 Faellen) und beim letzteren 90% (von 11 Faellen) einen Anfall bekamen, was zeigt, dass viel grössere ursächliche Bedeutung dem oberen Teil zukommt, als dem peripheren. Der Verfasser verfolgte dabei auch das Verhalten des Pulses, des Blutdruckes und der Atmung neben anderen Symptomen, verglich weiter mit dem Acetylcholininjektionsergebnis der Asthmatiker. Erkam dabei zum Schluss, dass die Reizung durch das Mittel und durch das sich dann bildende Sputum bezueglich des Entstehens des Asthmaanfalls die grässte Rolle spielt und stellte fest, dass die Acetylcholininhalation hauptsächlich auf den oberen Teil des Bronchialbaumes wirkt im Sinne der Anfallsentwicklung.
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  • Teijiro Tokuhisa
    1956 Volume 45 Issue 4 Pages 378-386
    Published: July 10, 1956
    Released: February 22, 2011
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    1) The author performed the fundamental tests by means of modified Holtroff-Koch's method for the determination of urinary 17-KS.
    2) The normal content of it was, on the average, 12.1mg. per day in men and 8.2mg. in women.
    3) Cortisone and DOCA did not increase urinary 17-KS, and ACTH increased, as a rule, it.
    4) Daily intravenous administration of T. T. G. increased it in cases with the normal content before the injection, but it seemed to be indefinite that whether or not urinary 17-KS was increased in cases with the decreased content before the injection.
    5) Every other day intravenous administration of typhoid vaccine showed an irregular fluctuation of urinary 17-KS in the early stage, but the fluctuation became stable as the injection is continued.
    6) Rectangular low frequency current therapy did not increase urinary 17-KS as long as it is within cure dose.
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  • 1956 Volume 45 Issue 4 Pages 387-403
    Published: July 10, 1956
    Released: February 22, 2011
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