The effect of Hp on resistance of Hb to acid denaturation is further confirmed by the CD spectra measurements and the CD spectra of acid denatured human Hb were presented.
Another effect of Hp on regeneration of Hb
+ from acid denaturation was also clarified spectrophotometrically.
And from the facts that Hp decreases the peroxidase activity of acid stable Hb
+ such as ox Hb
+ or decreases that of human Hb
+ in neutral pH region, some modifications are proposed against the generally accepted concept that Hp enhances the peroxidase activity of Hb.
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