The Keio Journal of Medicine
Online ISSN : 1880-1293
Print ISSN : 0022-9717
ISSN-L : 0022-9717
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Volume 22, Issue 2
Displaying 1-4 of 4 articles from this issue
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  • CLINICAL AND LABORATORY STUDIES OF 22 PATIENTS WITH MEGALOBLASTIC ANEMIA
    MUNEMOTO ITO, MASAFUMI KAWATO, YOSHIO YONAHARA
    1973 Volume 22 Issue 2 Pages 59-75
    Published: 1973
    Released on J-STAGE: March 27, 2009
    DOIhttps://doi.org/10.2302/kjm.22.59
    JOURNAL FREE ACCESS
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    Clinical and laboratory studies of 22 patients with megaloblastic anemia were reported herein.
    The patients were grouped on the basis of pathogenesis of megaloblastic anemia.
    Group A: 12 patients with idiopathic megaloblastic anemia.
    Group B: 10 patients with secondary megaloblastic anemia. In 5 patients megaloblastic anemia was associated with gas trectomy, in 3 patients with operation of small intestine and in 2 patients with drugs.
    The common presenting symptoms were palpitation and general fatigue.
    The erythrocyte count was ranged between 860, 000 and 4, 980, 000 per mm3. Patients with severe anemia mostly showed leucopenia and thrombocytopenia. When anemia was severe, promegaloblasts and basophilic megaloblasts were recognized in bone marrow. The serum iron was usually normal or raised, and high levels of LDH were recognized. The Schilling test for 14 cases revealed vitamin B12 absorption ratio to be so low as 0.346.1 per cent.
    Hematological findings were rapidly improved by administration of vitamin B12 in all cases except 2 cases with severe heart failure.
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  • EFFECT OF FENTANYL ON PENDULAR ROTATION NYSTAGMUS IN SQUIRREL MONKEYS
    JIN KANZAKI, MAKOTO IGARASHI, HIDEO MIYATA, W. K. WRIGHT
    1973 Volume 22 Issue 2 Pages 77-83
    Published: 1973
    Released on J-STAGE: March 27, 2009
    DOIhttps://doi.org/10.2302/kjm.22.77
    JOURNAL FREE ACCESS
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    Pendular rotation nystagmus was repeatedly investigated in squirrel monkeys after injecting Fentanyl in different doses. Good nystagmic in-hibition was observed although the slow phase eye movement remained after more than 0.027 mg/kg of the drug was administered. Sequential tests demonstrated the pattern of nystagmic suppression and its recovery along the post-injection time course.
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  • NEUROSURGEON'S INTEREST IN EXOPHTHALMOS
    PART 1. DIAGNOSIS OF EXOPHTHALMOS
    HIROKAZU NATIO, KAZUMA ADACHI, SHIGEO TOYA
    1973 Volume 22 Issue 2 Pages 85-91
    Published: 1973
    Released on J-STAGE: March 27, 2009
    DOIhttps://doi.org/10.2302/kjm.22.85
    JOURNAL FREE ACCESS
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    The authors propose the way of the approach to the exophthalmos. In most of exophthalmos, the clinical diagnosis is adequately confirmed by the supportive laboratory finding. When the possibility of malignancy can not be ruled out, further investigation such as biopsy or surgical exploration will be necessary.
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  • NEUROSURGEON'S INTEREST IN EXOPHTHALMOS
    PART 2. SURGICAL APPROACH
    HIROKAZU NAITO, TOORU NAKANISHI, SHIGEO TOYA, TADAHIRO TAKATSUKA, MASA ...
    1973 Volume 22 Issue 2 Pages 93-99
    Published: 1973
    Released on J-STAGE: March 27, 2009
    DOIhttps://doi.org/10.2302/kjm.22.93
    JOURNAL FREE ACCESS
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    The authors experienced the considerable variety of the orbital or para-orbital diseases which manifested exophthalmos. Because of the variable etiologies, the surgeons must evaluate the patient carefully in order to get the best management. Highly individualized approach is necessary to make the correct diagnosis and the cooperative work among the different specialities may be most rewarding in this field.
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