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Volume 17 (1988)
- Issue 6 Pages 1637-
- Issue 5 Pages 1559-
- Issue 4 Pages 1459-
- Issue 3 Pages 817-
- Issue 2 Pages 401-
- Issue 1 Pages 1-
Volume 17, Issue 4
Displaying 1-16 of 16 articles from this issue
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[in Japanese]1988 Volume 17 Issue 4 Pages 1459
Published: August 15, 1988
Released on J-STAGE: October 07, 2011
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P. M. GALLETTI, P. AEBISCHER1988 Volume 17 Issue 4 Pages 1461-1468
Published: August 15, 1988
Released on J-STAGE: October 07, 2011
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V. I. SHUMAKOV1988 Volume 17 Issue 4 Pages 1469-1475
Published: August 15, 1988
Released on J-STAGE: October 07, 2011
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John T. WATSON1988 Volume 17 Issue 4 Pages 1476-1480
Published: August 15, 1988
Released on J-STAGE: October 07, 2011
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Zi Bin YANG, Hui CHEN, Jing ZHONG, Xin WU1988 Volume 17 Issue 4 Pages 1481-1483
Published: August 15, 1988
Released on J-STAGE: October 07, 2011
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T. TOYOSHIMA1988 Volume 17 Issue 4 Pages 1484-1490
Published: August 15, 1988
Released on J-STAGE: October 07, 2011
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Y. KITANO, M. MINESHIMA, T. SANAKA, K. OTA1988 Volume 17 Issue 4 Pages 1491-1496
Published: August 15, 1988
Released on J-STAGE: October 07, 2011
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S. MANABE, T. TSURUMI1988 Volume 17 Issue 4 Pages 1497-1503
Published: August 15, 1988
Released on J-STAGE: October 07, 2011
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S. SAKI, K. TOJO, T. MIYAHARA1988 Volume 17 Issue 4 Pages 1504-1512
Published: August 15, 1988
Released on J-STAGE: December 02, 2011
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M. WATANABE, H. OHYANAGI, Y. SAITOH1988 Volume 17 Issue 4 Pages 1513-1522
Published: August 15, 1988
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSFluosol-DA has been known to induce a transient anaphylactic reaction in dogs. There were no consistent findings concerning this adverse reaction in human. The present study was undertaken to clarify the mechanism and to prevent the anaphylactic reaction by drugs. The anaphylactic reaction was featured by the systemic hypotension, pulmonary hypertension, leucopenia, and accompanied with a fall in serum complement titer and increases in histamine and thromboxane B2 levels in plasma. Prednisolone inhibited completely the activation of dog serum complement in vitro and pretreatment with this drug prevented remarkably the adverse reactions in vivo. Pretreatment with histamine H1 and H2-receptor antagonists in combination prevented remakably the systemic hypotension alone, but and pretreatment with indomethacin did the rise in thromboxane B2 level in plasma and pulmonary hypertension. Moreover, new PFC, FMIQ emulsion having no activation effect of serum complement induced no anaphylactic reactions in dogs. These results suggested that the activation of serum complement may be the initial step for the anaphylactic reaction, and that histamine may be the main adverse substance responsible for the systemic vascular reaction and thromboxane A2 responsible for the pulmonary response.View full abstractDownload PDF (3346K) -
Y. TOMIZAWA1988 Volume 17 Issue 4 Pages 1523-1528
Published: August 15, 1988
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSWe have developed a small-caliber vascular graft with an ID of 2.5 to 3.0mm by chemical modification of canine acellar carotid artery using a hydrophilic crosslinker, polyepoxy compound (PC). For the control, glutaraldehyde (GA) treated grafts were prepared. Sixteen dogs were used, 11 for the new graft and the other 5 for the control. A segment of the graft, 6cm in length, was implanted in the carotid artery. Sodium heparin was given during the surgery, but no anticoagulant was used there after. The compliance of the new graft was similar to that of the native artery. No excessive bleeding was noticed at the anastomotic sites. The patency rate was 77% during the longest observation period of 71 days whereas in the control, it was 10%. Microscopic observation revealed that on the inner surface of the new graft on the 7th P. O. D., endothelial like cells had appeared near the anastomotic lines. And at the same time, fibroblast infiltration in the graft wall was observed. These findings suggest that the reduction in initial bleeding is due to the high flexibility of the PC-treated graft and that the improved patency is caused by the blood element-repelling effect of the poly (ethylene glycol) chains of PC. Furthermore, the healing process is considered to be significantly enhanced by the accummulation of adhesive proteins such as fibronectin in the hydrogel layer on the surface of the graft. From these results, there is a high possibility for this new graft, with its many advantages, to be used clinically, as for example, a coronary bypass graft.View full abstractDownload PDF (11547K) -
S. SHINDO, A. TAKAGI, Y. TADA, Y. IDEZUKI1988 Volume 17 Issue 4 Pages 1529-1533
Published: August 15, 1988
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSWe have investigated to constitute a canine vascular model in vitro. Three dogs were used for this research, making a vascular model from each dog. Bilateral jugular veins were removed aseptically from an adult mongrel dog. Venous endothelial cells (ECs) and smooth muscle cells (SMCs) were harvested by using collagenase, plated on the culture flasks. SMCs were tripsynized, making cell suspension, and mixed with collagen solution in the culture tube. The collagen tube populated with SMCs was formed around a mandril, which was covered with a Dacron mesh for reinforcement. Autogenous ECs were tripsynized to make cell suspension and seeded onto the collagen tube. The microscopic examination showed the EC-monolayer on the collagen populated with SMCs, suggesting a possible canine vascular model.View full abstractDownload PDF (6826K) -
T. OKOSHI1988 Volume 17 Issue 4 Pages 1534-1542
Published: August 15, 1988
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSA new cardiac wall substitute was developed. This was composed of collagen-coated ultra-fine polyester mesh (CUFP) which was cross-linked by a hydrophilic polyepoxy compound. The CUFP was sutured as a patch in the right ventricular outflow tract of 19 dogs and was evaluated for up to 28 days after the implantation. The glutaraldehyde treated equine pericardial xenograft was used for the control of 16 dogs. The CUFP was very easy to handle because it was of suitable thickness and pliability and was easier to suture than the control. Observation of the resected specimens revealed that almost no thrombus formation was recognized on the inner surface of the CUFP probably due to its hydrophilicity. In the controls, however, 2-3mm thick thrombi were noticed along the suture line on the 4th to 7th day and on the center of the patch on the 28th day after the implantation. Light-microscopic observations showed that the uniformly thin neointima had grown and endothelial cells were seen in the peripheral portion of the patch. On the other hand, a detaching tendency of the thrombus and the neointima was observed and the neointima was formed unevenly in the control. It was concluded that the CUFP was superior to the control with regard to ease in suturing, antith. rombogenicity, and healing quality within a short observation period. Moreover, as the collagen of the CUFP is gradually dissolved and is replaced by the host cells, the CUFP should be reconstructed to form a new cardiac wall and therefore not degenerate with long-term use.View full abstractDownload PDF (13733K) -
M. TAGO, H. TERAOKA, K. BANDO, E. IKEDA, H. UCHIDA, S. TERAMOTO1988 Volume 17 Issue 4 Pages 1543-1545
Published: August 15, 1988
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSVenous reconstructions were performed by prosthetic grafts in six cases of superior vena cava (SVC) syndrome. The patients were from 3 to 66 year-old (average 48 year-old), four males and two females. The causes of SVC syndrome were thymomas in five cases and fibrosing mediastinitis in one case. In four cases, both SVC and left brachiocephalic vein were replaced by prosthetic grafts. Only SVC was replaced in one and left brachiocephalic veins in one. Ten prosthetic grafts were used, four were woven-Teflon and six were E-PTFE grafts. Three of woven-Teflon grafts were occluded and all of six E-PTFE grafts were patent. Four of thymomas and one fibrosing mediastinitis were dead. One case died within a month after operation. One is alive more than 2 years after operation without symptom of SVC syndrome. In our experience E-PTFE grafts showed better result in patency than woven-Teflon grafts. we think that E-PTFE graft is a good material for venous reconstruction of SVC syndrome.View full abstractDownload PDF (333K) -
[in Japanese]1988 Volume 17 Issue 4 Pages 1546-1547
Published: August 15, 1988
Released on J-STAGE: October 07, 2011
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[in Japanese], [in Japanese]1988 Volume 17 Issue 4 Pages 1548-1549
Published: August 15, 1988
Released on J-STAGE: October 07, 2011
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