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Volume 8 (1979)
- Issue 6 Pages 536-
- Issue 5 Pages 489-
- Issue 4 Pages 425-
- Issue 3 Pages 379-
- Issue 2 Pages 335-
- Issue 1 Pages 1-
Volume 8, Issue 4
Displaying 1-13 of 13 articles from this issue
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[in Japanese]1979 Volume 8 Issue 4 Pages 425
Published: August 15, 1979
Released on J-STAGE: October 07, 2011
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[in Japanese], [in Japanese], [in Japanese], [in Japanese]1979 Volume 8 Issue 4 Pages 427-435
Published: August 15, 1979
Released on J-STAGE: October 07, 2011
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M. SUZUKI1979 Volume 8 Issue 4 Pages 436-439
Published: August 15, 1979
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSIn vivo experiments of direct hemoperfusion were performed on acute kidney insufficient dogs using the adsorbents Amberlite XAD-4, Amberlite XAD-2 and Pamead.
The following results have been obtained from the above mentioned experiments:
There is no hemolysis in Amberlite XAD-2 or XAD-4 without coating. However, in Pamead, a great deal of hemolysis and clotting occurs in the same condition. BUN is not adsorbed by all of the adsorbents. On the other hand, in Pamead only 6% of creatinine is adsorbed per hour. Furthermore, the adsorbent efficiency of uric acid is 29.1% in Amberlite XAD-2, 40.6% in Amberlite XAD-4 and in Pamead. No electrolytical imbalance has been shown in XAD-4. But there in a 4% decrease of calcium found in Pamead and a Potassium decrease of 12% found in Amberlite XAD-2. Also, we can see pancytopenia in all kinds of adsorbents, especially in Pamead. Whereas Amberlite XAD-2 shows a 59% decrease of platelets, Amberlite XAD-4 shows a decrease of less than 32%. Pamead shows only clotting, so we can't use it without using the coating.
To conclude, we can generally obtain good in vivo results in Amberlite XAD-4, if consider the clinical use of Amberlite XAD-4 without coating.View full abstractDownload PDF (522K) -
T. KAKIUCHI, T. AOKI, H. MABUCHI, Y. MURAO, Y. TABATA, Y. KISHI, H. NA ...1979 Volume 8 Issue 4 Pages 440-445
Published: August 15, 1979
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSC. O. changes between overhydration group and good-controlled one by water balance before, during and after hemodialysis were evaluated in this study.
During it they were grossly classified into two different C. O. patterns. Overhydration group showed type A C. O. pattern (Y=aX2+bX+c, a<0, b>0) and good-controlled, type B C. O. pattern (Y=aX+b, a<0).
In comparison with C. O. changes at predialysis and postdialysis that we measured 10 minutes after completion of return of coiled blood, between two groups, three different subgroups such as increased, non-changed and decreased at postdialysis, were present respectively. Hence, imaginary considerations based on only comparative data between predialysis and postdialysis may be impossible to explain intradialytic hemodynamics because of progressing remarkable hemodynamic changes during it.
Intradialytic disequilibrium syndrome such as nausea, vomiting, jawning, general lassitude or abdominal discomfort started to appear at level of C. O. reduction of 1.5-2.0l/min from initial C. O. Several cases of shock were experienced and their C. O. values, then, were less than 3.0l/min. By rapid infusion with approximately 200ml of 5% D/W, however, C. O. was increased markedly and instantaneously, and it is generally sufficient to be recovered from shock-state as well as intradialytic disequilibrium syndrome. Judging from these facts it might be possibly true that hemodynamic changes, at least, are contributory directly and indirectly to the appearance of this syndrome.View full abstractDownload PDF (745K) -
T. NISHIMOTO, S. SASAKI, H. KISHIDA, S. KAKIMOTO, A. TAKEUCHI, M. OHZE ...1979 Volume 8 Issue 4 Pages 446-449
Published: August 15, 1979
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSSince April 1976, we have been checking patients with implanted pacemakers using a pacergraph and a pulse-counter. Our observation indicates that changes in spike width precede changes in pulse rate when the energy of a mercury-zinc pacemaker is declining.
With a lithium-iodide pacemaker whose spike width is shorter, measurement of pacing threshold at the same spike width as the pacemaker which is going to be used is important.View full abstractDownload PDF (442K) -
H. OHUCHI, A.T., Jr. YOKOBORI, H. SASAKI, T. MAEYAMA, T. YOKOBORI, T O ...1979 Volume 8 Issue 4 Pages 450-459
Published: August 15, 1979
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSAs a first step of the estimation of the anastomosis part of blood vessel and vascular substitute in vivo state, we proposed double anastomosis test method which can estimate conveniently and effectively the influence of mechanical factors on the damage and durability of the anastomosis part of blood vessel and vascular substitute in vitro state using the experimental apparatus we designed simulated of wind kessel theory as elastic model of artery system.
Experiment by this test method was carried out on bovine graft, Dacron double velour vascular substitute anastomosed by blood vessel. The experimental results obtained were discussed.View full abstractDownload PDF (7548K) -
T. NAKASHIMA, K. TAKAKURA, Y. KOMOTO, N. NAKABAYASHI, T. INOU1979 Volume 8 Issue 4 Pages 460-465
Published: August 15, 1979
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSBead active carbon from petroleum was coated with a blood compatible polymer derived from hydroxyethyl methacrylate (HEMA) and studied basically for direct hemoperfusion (DHP).
Bead active carbon coated with HEMA-based polymer showed a high efficiency of adsorption, especially for the middle molecular weight substances, and prevented release of microparticles. Elution of the organic substances from the coating layer when autoclaved was also prevented by copolymerization of HEMA and a self-curable comonomer. The in vivo experiments showed excellent blood compatibility of this system.
Based on these promising results of performance and safety, this adsorbent system is now being evaluated clinically, mainly for the treatment of drug intoxication, hepatic coma, and chronic renal failure with uremic neuropathy.View full abstractDownload PDF (2770K) -
Y. MITAMURA, K. YAMAMOTO, T. MIKAMI, M. TAKAHASHI, T. NALAMURA, K. NIS ...1979 Volume 8 Issue 4 Pages 466-469
Published: August 15, 1979
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSPneumatic driven diaphragm type left ventricular assist device (LVAD) was developed. The LVAD consists of inflow and outflow tissue valves (porcine aortic valves), polyurethane diaphragm and glutaraldehyde treated bovine pericardium lining. The LVAD was implanted in dogs between the left ventricle (LV) and the aorta to examine the hemodynamic effects on the heart. Myocardial oxygen consumption was 1.99±0.43 ml/min/100g (n=10) in the control and was significantly reduced to 1.17±0.16 (n=10) during LV bypass (p <0.001) . Coronary sinus blood flow decreased to 16.3±5.1 ml/min/100g(n=10) during LV bypass from 24.1±8.2 (n=10) in the control (p<0.001). Arterial-venous oxygen content difference was 8.74±1.89 vol% (n=10) in the control and 7.55±1.59 (n=10) during LV bypass (p<0.01). The developed LVAD is effective for cardiac assist.View full abstractDownload PDF (6387K) -
[in Japanese]1979 Volume 8 Issue 4 Pages 470
Published: August 15, 1979
Released on J-STAGE: October 07, 2011
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Paulo T. HIRAYAMA1979 Volume 8 Issue 4 Pages 471-472
Published: August 15, 1979
Released on J-STAGE: October 07, 2011
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[in Japanese]1979 Volume 8 Issue 4 Pages 472-473
Published: August 15, 1979
Released on J-STAGE: October 07, 2011
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[in Japanese]1979 Volume 8 Issue 4 Pages 474-475
Published: August 15, 1979
Released on J-STAGE: October 07, 2011
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[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...1979 Volume 8 Issue 4 Pages 476-480
Published: August 15, 1979
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSDownload PDF (3687K)
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