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Volume 27, Issue 3
Displaying 1-12 of 12 articles from this issue
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[in Japanese]1998 Volume 27 Issue 3 Pages 585
Published: August 15, 1998
Released on J-STAGE: October 07, 2011
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[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...1998 Volume 27 Issue 3 Pages 588-590
Published: August 15, 1998
Released on J-STAGE: October 07, 2011
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H OGUCHI, Y NAKANO, M KOBAYASHI, T SODEYAMA, K HORA1998 Volume 27 Issue 3 Pages 591-600
Published: August 15, 1998
Released on J-STAGE: October 07, 2011
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Y NOISHIKI1998 Volume 27 Issue 3 Pages 601-607
Published: August 15, 1998
Released on J-STAGE: October 07, 2011
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K MAEDA, T SHINZATO1998 Volume 27 Issue 3 Pages 608-613
Published: August 15, 1998
Released on J-STAGE: October 07, 2011
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Y OSADA, M NISHINO1998 Volume 27 Issue 3 Pages 614-619
Published: August 15, 1998
Released on J-STAGE: October 07, 2011
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M NAKAO, M YAMAMOTO1998 Volume 27 Issue 3 Pages 620-629
Published: August 15, 1998
Released on J-STAGE: October 07, 2011
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M SHINOHARA, H KURODA, H MAKINO, E SATO, Y FUKAYA, J AMANO1998 Volume 27 Issue 3 Pages 630-633
Published: August 15, 1998
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSWe examined the use of an accelerometer to detect skeletal muscle fatigue. Latissimus dorsi muscle flaps were made in 7 mongrel dogs. The flap was wrapped once around the chamber installed in a mock circuit with 10 mmHg of preload and 30 mmHg of afterload. The accelerometer (PKS1-4A1: Murata, Kyoto) was inserted between the chamber and the muscle flap. The muscle flap contracted using burst stimuli. The pump output and the accelerometer voltage were measured 1, 3, 5, 10 and 15 min after the beginning of stimulation. These values were expressed as a percentage of the values at 1 min. The pump outputs at 3, 5, 10 and 15 min were 56±18%, 42±17%, 30±18% and 22±19%, respectively. The voltage readings of the accelerometer over the same time intervals were 70±22%, 64±31%, 51±24% and 45±23%, respectively. A high positive correlation was found between the pump output and the accelerometer voltage. These data suggest that skeletal muscle fatigue can be effectively detected with a system using an accelerometer.View full abstractDownload PDF (2166K) -
Y TAKEWA, E TATSUMI, I TAENAKA, T NAKATANI, T MASUZAWA, T NISHIMURA, M ...1998 Volume 27 Issue 3 Pages 634-640
Published: August 15, 1998
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSHemodynamic and humoral conditions under various pulmonary blood flow during venoarterial bypass (VAB) were quantitatively investigated in a series of chronic animal experiments. A biventricular bypass system was installed in 6 adult goats weighing 50.0±1.1 kg. Two weeks later the extracorporeal circuitry was changed to VAB without anesthesia. The PAF was reduced stepwise from 100% to 50, 25, 10 and 0% of total systemic flow. The mean aortic pressure (mAoP) and systemic vascular resistance (SVR) decreased in proportion to the decrease in PAF and caused a sort of shock state at 0% PAF. The prostaglandin E2 (PGE2) concentration increased following the decrease in PAF from 100 to 0%. The renin-angiotensin system increased in proportion to the decrease in PAF. In contrast, the catecholamines concentrations did not change appreciably even at 10% PAF, but were markedly elevated at 0% PAF. The antidiuretic hormone level similarly changed. In conclusion, decrease in PAF during VAB exerts significant effects on the hemodynamics. The changes in the levels of vasodilators, especially PGE2, may play a substantial role in the decrease in SVR, whereas changes in vasoconstrictors are likely to be a secondary reaction to the decrease in mAoP.View full abstractDownload PDF (3329K) -
-The Performance of Prototype Device and Drug Delivery-T ITOH, T NOGUCHI, H NONOGI, T MATSUDA, T SUGAWARA, T ARAI, K KANDA, N ...1998 Volume 27 Issue 3 Pages 641-646
Published: August 15, 1998
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSWe have developed a new balloon catheter device with multifunction: inflation of coronary stenosis, drug delivery, and perfusion of distal vessel and evaluated in vitro and in vivo using canine model. This balloon catheter has eight perfusion ports at the proximal site of balloon, and a drug delivery port at the distal site of balloon. Extended balloon distal tube was used as drug delivery region. The flow-rate was obtained around 42 cc to 52 cc/min. The simulated drug was stained in the drug delivery region under the low pressure in balloon inside with continuous infusion (1 cc/min.), whereas the simulated drug was wash out without continuous infusion. The distal perfusion % flow-rate was obtained 12.2±5.9% comparing with control in a dog carotid artery. A continuous infusion of both FITC-labeled drug resulted in its local accumulation on and in a injured vessel wall, respectively. This new device may promise to realize local delivery of therapeutic agents at the balloon injury site after mechanical balloon dilatation to protect restenosis.View full abstractDownload PDF (7252K) -
[in Japanese]1998 Volume 27 Issue 3 Pages 647-648
Published: August 15, 1998
Released on J-STAGE: October 07, 2011
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[in Japanese], [in Japanese]1998 Volume 27 Issue 3 Pages 649-650
Published: August 15, 1998
Released on J-STAGE: October 07, 2011
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