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Volume 24, Issue 4
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[in Japanese]1995 Volume 24 Issue 4 Pages 907
Published: August 15, 1995
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSDownload PDF (184K) -
T SHIMIZU, M HASHIMOTO, H SUESADA, S ISHIMARU, K IZUMI1995 Volume 24 Issue 4 Pages 909-914
Published: August 15, 1995
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSThe centrifugation and washing process of the autotransfuser removes plasma protein of blood from the surgical field. In order to promote recovery from hypoproteinemia after intraoperative salvaging autotransfusion, the salvaging of plasma protein collected in the waste bag of the autotransfuser was investigated in 11 patients undergoing cardiovascular surgery. Selective free-hemoglobin absorbent consisting of silica-gel beads was applied to remove large amounts of free-hemoglobin in the autotransfuser waste bag, a hemoconcentrator was used to remove saline, and a microfilter was placed in the circuit to remove platelet aggregates. The patients were divided into two groups: one column filled with the absorbent was used in 8 cases, two columns were used in 3 cases (one column could absorb approximately 10g of free-hemoglobin). In 6 cases in which the free-hemoglobin volume in waste was within the absorbing capacity of the column, most of the free-hemoglobin in waste was successfully absorbed and 70-90% of albumin or immunoglobulin could be saved with one column, but only 50% of albumin could be saved with two columns. Plasma protein in the waste bag of the autotransfuser might be saved by this method using free-hemoglobin absorbent, however, matching the volume of the absorbent to the shed blood volume was considered to be important to increase the recovery rate of plasma protein.View full abstractDownload PDF (2407K) -
T SUEDA, S FUKUNAGA, N MITSUI, Y KOURA, Y HOTEI, Y MATSUURA1995 Volume 24 Issue 4 Pages 915-918
Published: August 15, 1995
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSAn intravascular oxygenator (IVBO), consisting of silicone hollow fiber (external diameter 2mm, internal diameter 1.6mm, membrane width 0.2mm) and tubes for air-driving, was devised and evaluated for its effectiveness of oxygenation and circulatory assistance. Both edges of the balloon were fabricated to the silicone tubes (the oxygen inlet and the oxygen outlet), connecting to the outlets of the airdriven artificial heart driver and the vacuum pump. While the driver sent high-pressure oxygen, the balloon was inflated, therepy adding oxygen to the blood. The balloon was deflated by vacuum pressure of the driver. The balloon was pumping as a circulatory assist pump and it served as an oxygenator simultaneously. A preliminary experiment using a vessel model showed that the pump output of the IVBO was 40ml/min under the condition of 60mmHg driving pressure, —150mmHg vacuum pressure and 40% systole. Blood oxygen pressure increased during pumping, according to the increase of driving pressure and percent systole. An animal experiment in which the IVBO was implanted into the inferior vena cava of a mongrel dog, showed an increase of venous return and oxygen pressure of the venous blood during pumping.View full abstractDownload PDF (2677K) -
K IZUTSU, S NITTA, T YAMBE, S NAGANUMA, Y KAKINUMA, H AKIHO, S KOBAYAS ...1995 Volume 24 Issue 4 Pages 919-923
Published: August 15, 1995
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSIn order to determine the effect of the oscillated blood flow on pulmonary circulation, partial right heart bypass using the VFP was performed in five adult goats. Time series data of the pulmonary arterial flow and pulmonary arterial pressure recorded to estimate the effect of oscillated blood flow on the pulmonary circulation. Pulmonary arterial resistance (PAR) and pulmonary arterial characteristic impedance (PACT) were not significantly changed. But during 30Hz flow, PAR and PACT were slightly increased. This result suggests that frequency of blood flow affects characteristics of pulmonary circulation.View full abstractDownload PDF (719K) -
A TSUKAMOTO, Y TAKANO, Y EZAKI, M TAKAHASHI, Y KOBARAI1995 Volume 24 Issue 4 Pages 924-930
Published: August 15, 1995
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSThe antithrombogenesity and histocompatibility of a fibrin matrix was evaluated under various conditions. Vascular grafts coated with the fibrin polymer or monomer were implanted in the abdominal aortae of rabbits. The cell ingrowth was observed up to the middle of the fibrin polymer coated graft. It was indicated that ionic strength and thrombin-fibrinogen ratio (T/F ratio: U/mg) of the fibrin matrix influence matrix characteristics; anti-fibrinolysis, multiplication rate of cultured vascular endothelial and smooth muscle cells, platelet stimulation and fibrin formation. A suitable matrix was found to have an ionic strength index of 0.20 and T/F ratio of 0.071, 0.180. In dog carotid arteries, cell ingrowth in implanted vascular grafts with fibrin matrix of T/F ratio, 0.180 was more efficient than those with T/F ratio, 0.071. Our observations suggested that fibrin polymer matrix with ionic strength of 0.20 and T/F ratio of 0.180 has improved anti-thrombogenesity, promotes healing and should be suitable for small caliber vascular prosthesis.View full abstractDownload PDF (7015K) -
-Patients with low ADL level-J ANBE, K KASAHARA, Y OGURA, H NAKAJIMA, Y EGOH, T AKASAKA, K HATSUSE, ...1995 Volume 24 Issue 4 Pages 931-937
Published: August 15, 1995
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSTwo cases with pacemaker infection in a remote phase are reported with association of statistical analysis of pacemaker patients between in private and in university hospital. Case 1: a fourty-seven-year-old male with old cerebral infarction and right hemiplegia received reoperation six months after the initial implantation due to infection in the pacemaker pocket. S aureus was positive by cultivation of punctured fluid. Case 2: a fifty-seven-year-old male patient was treated with reimplantation of pacemaker because of infection of pacemaker eight months after initial implantation. Statistical analysis showed significantly frequent complication of urinary tract infection and cerebral infarction, and in the contrast, significantly low grade of ADL in private hospital patients group (p<0.001).View full abstractDownload PDF (1032K) -
T AZAMI, M OKADA, N YOSHIMURA, H NOHARA, K ATAKA, T OTA1995 Volume 24 Issue 4 Pages 938-940
Published: August 15, 1995
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSWe have developed a ventricular assist cup which did not contact the blood directly. We performed an experimental study to evaluate the effect of this system for circulatory support in 2 mongrel dogs. The cup, whose form is like wineglass, attaches to ventricular wall and consists of inner flexible diaphragm and outer hard housing. Diaphragm via positive pneumatic force compress ventricular wall directly during systole. Under ventricular assist cup actuation, hemodynamic parameters were improved as follows; systemic arterial pressure: 69-72/48-52→91-95/49-54mmHg, cardiac output: 0.7-0.80→1.2-1.3l/mm, before and after actuation, respectively. Systemic arterial pressure of 80/38mmHg and cardiac output of 1.0l/min could be maintained using this device for a fibrillated heart. In conclusion, this ventricular assist cup is a beneficial alternative as circulatory support system without contacting blood directly.View full abstractDownload PDF (1550K) -
-Investigations of optical coupler and modulationT YASAKI, Mojtahedi HA, H YASUE, K KOSHIJI, E SHU, T UTSUNOMIYA, S NIW ...1995 Volume 24 Issue 4 Pages 941-946
Published: August 15, 1995
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSTranscutaneous telemetry system without corrosion of the skin is indispensable for driving TAH. Several informations inside body can be transmitted to outside body using transcutaneous optical coupler constructed by LED embeded under the skin and PD attached to the outer surface of it. In this paper we investigated optical transmission characteristics of the skin and optimum direction angle of LED to construct fine transcutaneous optical coupler against dislocation between the optical devices. We found that in the optical transmission through several parts of the skin of goat and cow, the lights of wavelengths of 850nm and 1, 100nm are attenuated smaller than the other wavelengths, and in case of the skin thickness of 4mm the direction angle of LED of 23.5 degrees is most optimum against the eccentric deviation between the optical devices. And we also investigated modulation method to improve information transmission characteristics. We used the ASK modulation method, and evaluated the information transmission.View full abstractDownload PDF (810K) -
-Quantitative evaluation of pooling of heparin coated oxygenatorsN MOMOSE, T INO1995 Volume 24 Issue 4 Pages 947-951
Published: August 15, 1995
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSThe blood pooling inside the oxygenator may make blood coagulation, especially during assist circulation because of low dose heparin. The purpose of this study is to evaluate the pooling of oxygenators quantitatively. The circuit including the oxygenator was perfused with distilled water (3.5μS/cm) at the speed of 2.0l/mm, then 10ml of saline (16, 050μS/cm) was injected at the influx of the oxygenator. At the efflux of the exygenator, electric conductivity (voltage) of the perfusate was measured, continuously. As oxygenators, Univox-Gold, Maxima-CB1380 and Capiox-II 50 (H) which are heparin coated oxygenators, were tested. In results, time from the point of maximum voltage (Vmax) to one of one fourth of Vmax (1/4 Vmax) were 11.2sec, 20.0sec and 16.8sec in Univox, Maxima and Capiox, respectively. In conclusion, the pooling of the oxygenator was smallest in Univox and smaller in Capiox than in Maxima.View full abstractDownload PDF (774K)
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