Chromatographic behavior of individual glycerolipid molecular species including highly polyunsaturated fatty acid bounded form was analyzed in detail. And a novel approach for the identification of glycerolipid molecular species on reverse phase chromatography rest on the additional theorem of chemical potential of individual functional groups in glycerolipid molecule was suggested. As an example of health benefit of phospholipid molecular species containing high amount of DHA, antitumor promotional effect of them were demonstrated, and they were successfully synthesized, then the synthesized and natural occurring ones were applied as antitumor boosting liposomes.

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Colloidal stability and growth processes (e.g., coalescence, Ostwald ripening) of oil droplets ultrasonically dispersed in water in the absence of any stabilizing agents (e.g., surfactants, amphiphilic polymers) (surfactant-free oil-in-water emulsions) were examined to evaluate the stabilization mechanism of oil-in-water emulsions and roles of stabilizing agents on colloidal stability. For example, surfactant-free oil droplets composed of longer-chain hydrocarbons were more stable in water than those of shorter-chain hydrocarbons. The addition of long-chain hydrocarbons (e.g., n-hexadecane, squalane) or hydrophobic polymers (e.g., polystyrene) into oil droplets enhanced colloidal stability of surfactant-free oil droplets dispersed in water. This paper summarizes advances on surfactant-free emulsion systems; (i) colloidal stability and growth processes of surfactant-free oil droplets dispersed in water, (ii) development of single-droplet detection technique for monitoring the droplet growth, (iii) the colloidal stabilization of oil-in-water emulsions with the addition of long-chain hydrocarbons or hydrophobic polymers into droplets, and with sequential megasonic irradiation and (iv) nano- and micro-scale material fabrication using surfactant-free emulsions

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