Vertical-multi-articulated robots are widely used in welding, handling and operating in manufacturing. It can be expected as an inexpensive and highly versatile AM that AM by welding overlay becomes possible by a robot which equip a welding torch using CO₂ gas. Since CAM-like software is not widely used in robot welding, the author tried to generate a torch pathway using Kodatuno as an alternative. In addition, the forming and cutting characteristics of the welding overlay were examined.

Nowadays, most of the strategies that commonly used to represent dynamic machining are based on three-dimensional (3D) geometric models and its motion with time steps information. These existing methods cause user to use shorter intervals, larger iteration number and longer calculation time if you need more precise result. We proposed a system to represent tool-workpiece engagement situation of dynamic machining process by four-dimensional (4D) geometric model based on Spatio-Temporal space. In the last report, the T-map method was proposed to simplify cutter-workpiece engagement analysis in 4D space. However, T-map method is more suitable for the situation between a static and a moving 3D object. This requires the user to convert the motion of workpiece to the cutter. Therefore, a method was considered for computing the general intersection between tool-occupied region and 4D mesh workpiece. Considering versatility, the boundary intersection determination method checks each pair of tetrahedrons and discusses case by case and get the intersection condition of tetrahedrons. However, it takes a lot of times for traversing all the tetrahedrons and analyzing according to the intersection situation. For accelerating the computation, parallel processing was introduced for optimizing preprocess and intersection determination steps.

For pathological diagnosis of cancer and other diseases, it is necessary to embed diseased tissues in paraffin and cut them into sections that have thickness of several micrometers to get preparations for microscopic observation. In this study, we aim to improve and stabilize the quality of pathological sections. In this paper, we will report the results of experimental measurements of cutting force and thickness of pathological sections of various specimen-embedded paraffin blocks and the investigation of factors affecting the cutting force and thickness based on mechanical model.

Monitoring the components in saliva is expected to be useful for early diagnosis. In this study, we integrated ion-selective-electrodes into a microfluidic channel device for measuring the ion concentration in saliva. All-solid-state selective electrodes were used for the electrodes to reduce the size of the device. In addition, by incorporating the electrode into the microfluidic channel, we were able to measure the ion concentration with small amount of sample. Solutions of different ion concentrations were introduced into the device, and the potential response was measured.

It is known that the mechanical structure on the culture substrate affects the cells. The purpose of this study was to clarify the effect of microstructure on cell adhesion. I conducted cell culture experiments on the microstructure and cell detachment experiments using microfluidics. The microstructure was fabricated on a glass substrate using MEMS method. The microfluidic channels made by PDMS were bonded to the microstructure substrate, and human lung cancer cells were seeded inside. The cells were observed under fluidic shear stress on the microstructure and on the glass substrate.

A general blood separation process is performed by centrifugation at a medical institution. In this study, we investigated a method of trapping blood cell components using a microchannel device. Ultimately, the purpose is to easily extract plasma components. This time, we created a stepped shape on the order of microns and implemented a method of physically trapping it. As a result, a step with a height of 1 micron and 3 micron could be fabricated. Then, we examined the possibility of trapping using fine particles of the same size as red blood cells.

Precise measurement is possible with a MEMS device fabricated by silicon etching. However, it is difficult to observe with a general transmission microscope due to the nature of the material. In this research, we made it possible to fabricate a highly transparent micro structure made of epoxy resin on a glass substrate. The fabrication method can be done by general photolithography, and the floating structure can be fabricated. It is also possible to directly observe biomaterials by taking advantage of their highly transparent properties.

The use of microalgae with phototaxis as microrobots can further reduce the size of microsystems. In this study, we aim to develop a density distribution control method using the negative phototaxis of Euglena. Euglena enclosed in a microspace was irradiated with a blue shrinking and moving microlight pattern using a multi-point light irradiation system. The density change was calculated from the cell density before and after the shrinkage and movement. We also investigated the effect of the microspace on the movement of Euglena.

Appropriate adjustment of NC parameters is indispensable for high speed and high accuracy of NC machine tools. However, parameter adjustment is currently performed empirically by skilled technicians. There is a trade-off between speed and accuracy, and it is difficult to make well-balanced adjustments. Therefore, a parameter adjustment method that realizes the desired speed, accuracy and low vibration is expected In this study, we evaluate the performance based on speed, accuracy and vibration, and propose a method for efficiently adjusting NC parameters by design of experiments.

Thermal deformation accounts for 70% of machining errors in machine tools. The latest improvements in sensor technology have enabled the robust estimation of thermal displacement by multi-point temperature data of the entire structure. However, the temperature of the feed drive system has not been measured directly so far because of the difficulty of data transmission and power supply. In this study, we developed a wireless multi-point temperature sensor system and measured the temperature of the ball screw. As a result of adding the temperature data at 25 points of the ball screw, the accuracy of the thermal displacement estimation was improved compared to that of only 277 points of the structure.

For a high-precision and high-speed processing machine, we consider a trajectory tracking system with a coordinated controlled dual-stage. The dual-stage has two axes, one has wider range of actuation and lower band width which named slower-axis, another has shorter range of actuation and higher band width which named faster-axis.In this research, we propose a method for separation of a time series of tool position command into the slower- and faster- axis position command by using a B-spline basis function considering with actuation limit of the faster axis. And we show a method of coordinated control.