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Volume 34 (1982)
- Issue 6 Pages 413-
- Issue 5 Pages 335-
- Issue 4 Pages 207-
- Issue 3 Pages 147-
- Issue 2 Pages 101-
- Issue 1 Pages 1-
Volume 34, Issue 2
Displaying 1-4 of 4 articles from this issue
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—As a Marker for Measuring Fetal Maturity—Tomoakl KAWAMURA, Sachlo OGITA1982 Volume 34 Issue 2 Pages 101-109
Published: March 01, 1982
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSAcid protease activity of 65 amniotic fluid specimens ranged 17 to 41 weeks of gestation was measured by use of a minor modification of Northrop's method to examine a possible relationship between the enzyme levels and fetal maturity. As a reult, pH 1.9 active acid protease levels showed a marked increase after 36 weeks of gestation, while pH 3.7 active acid protease levels revealed a gradual increase as fetal age progresses. It was found that pH 1.9 activity over 0.300 manifested by OD 280nm discriminated fetal age over 36 weeks of gestation with accuracy of 96.7%. Moreover, the level of pH 1.9 active acid protease proved to be highly correlated with fetal wieght irrespective of weight gain within a week after the amniocentesis. Correlation equation was expressed by a linear regression of Y=1238X+2361 (n=30, r=0.89) where Y: fetal weight, X: OD 280nm, Further, the origin of acid protease in the amniotic fluid was investigated, and it disclosed fetus itself to be the source of supply. Based on the result, the physiological significance of an increase of the enzyme activity in relation to fetal age and weight may be interpreted as signifying the maturity of fetal digestive function in preparation for extrauterine life.View full abstractDownload PDF (1136K) -
Osamu ISHIKO1982 Volume 34 Issue 2 Pages 111-122
Published: March 01, 1982
Released on J-STAGE: December 02, 2011
JOURNAL FREE ACCESSThe erythrocyte deformability was measured by filtration technique with the use of polycarbonate sieves (3μmφ, 5μmφ) and erythrocyte suspension of 2% cell in PBS albumin solution. In this system, flow velocity after t sec. can be expressed by a formula Vt=n0(1-e-ργτ)/γ, where n0: pore density p: viscosity of suspension, γ: non-deformable cell counts. The filterability of erythrocytes from term neonates was markedly lowered than that from adults and it decreased as lowering fetal age, which shows a gradual increase during the neonatal period. Each of the conditions, namely preservation at 37s°C, lowering pH and lowering temperature resulted in decreased deformability more sensitively in neonatal erythrocyte than adult erythrocyte. The results indicate that neonatal blood contains more non-deformable and/or functionally impaired cells than adult blood and that the deformability is dependent on energy and the energy metabolism is more active in neonatal erythrocyte than adult erythrocyte. The presence of a larger number of the pitted cells in the neonatal circulation could be logically explained by the immaturity of the spleen function. Therefore, neonatal erythrocyte deformability is apt to be affected more sensitively by the condition of body fluid. Accordingly, in view of the possibilities of causing decline in the erythrocyte deformability and the possibilities of impairing microcirculation by hypoglycemia, acidosis, hypoxia and hypothermia in labor, the supplement of glucose, the prevention of acidosis and the preservation of warmth are clinically very important.View full abstractDownload PDF (1529K) -
Naohlko UMESAKIT, Ounlan LEE, Hisao SAKO, Jyunko NAKADE, Tadashi SUGAW ...1982 Volume 34 Issue 2 Pages 123-134
Published: March 01, 1982
Released on J-STAGE: December 02, 2011
JOURNAL FREE ACCESSThe swelling of regional lymph nodes in patients with early cancer and histologscal findings of them suggested that immunocapacity of regional lymph nodes might play an important role in regional lymph node metastasis. However, the mechanism of metastasis in the lymph nodes is still obscure. Therefore, in this study, the change of immunocapacity of regional lymph node in patients with cervical cancer was measured in relation to tumor progression, especially lymph node metastasis, by using postoperative classigication of cervical cancer which was more precise than preoperative clinical stage (FIGO stage). Immunostatus of regional lymph nodes was measured by using mitogenic activity of mononuclear cells.
As a result, higher mononuclear cell reactivity in patients with carcinoma in situ was found as compared with benign one, but decreased with tumor progression. Cases with lymph node metastasis showed lower mononuclear cell reactivity to PHA or ConA as compared with cases without one.
One the other hand, mononuclear cell reactivity in peripheral blood of cancer patients had sligter decrease as compared with benign one. The immunological change in regional lymph nodes was examined by measuring both percentage and reactivity of T-lymphocytes collected from lymph nodes. Cases at early stage had slighter increase of percentages of T-lymphocytes and higher mononuclear cell reactivity as compared with benigh one, but they decreased with tumor progression.
These data suggest that decrease of immunocapacity in regional lymph node in relation to tumor progression may be a significant factor for accelerating regional lymph node metastasis.View full abstractDownload PDF (1245K) -
Goro TOSHISHIGE, Akira KUBOTA1982 Volume 34 Issue 2 Pages 135-137
Published: March 01, 1982
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSIn vaginal hysterectomies, we used to use silk sutures on the stumps of the uterine vessels, uterine adnexae and parametrial ligaments, except for cat-gut sutures on the vaginal stump. However, pathological granulations often grew at both corners of the vaginal stump, and were responsible for troublesome vaginal bleeding and/or profuse vaginal discharge, which often conti nued for over a half year after surgery.
Since May 1979, silk and cat-gut sutures have been replaced partially or totally by Dexon (a synthetic, absorbable thread) in 120 cases in our hospitals. In the first group of 62 cases, Dexon sutures were applied in places other than the stumps of the uterine vessels, where black silk suturesu were sed;nevertheless, 20 cases (30%) of excessive granulation on the vaginal stump were observed. In the second group of 58 cases, in which Dexon sutures were used in all ligations, excessive granulation appeared in only 2 cases (3.4%). These seem to be satisfactory results vis-a-vis the prevention of pathological granulation on the vaginal stump after surgery.
The usage of Dexon sutures in vaginal hysterectomy is thus recommended.View full abstractDownload PDF (316K)
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