巻号一覧
35 巻 (1982)
- 5-6 号 p. 203-
- 4 号 p. 143-
- 3 号 p. 87-
- 2 号 p. 41-
- 1 号 p. 1-
35 巻, 5-6 号
選択された号の論文の9件中1～9を表示しています
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SERVÉ NOTERMANS, JOHN DUFRENNE, SHUNJI KOZAKI1982 年 35 巻 5-6 号 p. 203-211
発行日: 1982年
公開日: 2010/03/19
ジャーナル フリーELISA was tested for the adequacy to differentiate between botulinum type C1 and D toxins. The results presented in this paper indicate antigenic relationship between type C1 and D toxins. Furthermore, indications were obtained that the antigenicities of type C1 and of D toxins produced by different strains are not identical. Although ELISA can be used to differentiate type C1 and D toxins from those of other types, the assay has only limited value to differentiate between type C1 and D toxins. No parallel relationship between toxicity (mouse bioassay) and toxin-related-antigen contents (ELISA) of C. botulinurn type C and D cultures was found.抄録全体を表示PDF形式でダウンロード (872K) -
北川 隆之, 赤松 穰1982 年 35 巻 5-6 号 p. 213-219
発行日: 1982年
公開日: 2010/03/19
ジャーナル フリーExternal ATP causes a passive permeability change in several transformed cells but not in untransformed mouse fibroblasts. In the present experiments, the ATP-specific permeability change was observed also in B16 melanoma and L929 cells. The sensitivity to external ATP of these cells increased further when the concentration of intracellular ATP was lowered by addition of a mitochondrial inhibitor. In contrast, mouse 3T3 cells transformed by murine sarcoma virus did not respond to external ATP even when the intracellular ATP was depleted. Such differences in the ATP-sensitivity were not ascribed to the different concentrations of intracellular ATP.抄録全体を表示PDF形式でダウンロード (668K) -
本井 重博, 青池 晟, 川井 啓市, 雨貝 孝, 岸田 綱太郎1982 年 35 巻 5-6 号 p. 221-230
発行日: 1982年
公開日: 2010/03/19
ジャーナル フリーThe present study demonstrates that human peripheral blood mononuclear cells (PMC) can be stimulated in vitro to become cytotoxic T lymphocytes (CTL) by PHA. A significant cytotoxic activity of PMC was detected 48 hr after the culture initiation in the presence of 5μg/ml of PHA and the peak level of the activity was obtained by culturing PMC for 72 hr. The cytotoxic cells require the presence of PHA as a cell agglutinin for the expression of their cytotoxic activity. The effector cells mediating the activity were identified as T lymphocytes by E-rosette fractionation of PMC. In this system, removal of carbonyl iron phagocytosed or attached cells from PMC did not abrogate CTL generation of PMC. In addition, human α-interferon did not augment CTL generation or expression of their activity. Although the target cells employed were sensitive to natural killer (NK) cells, the effector cells induced by PHA did not seem to have any relation to the NK cells. The present study may provide a useful tool to analyze for precursors of killer T cells.抄録全体を表示PDF形式でダウンロード (943K) -
藤原 博, 倉塚 和夫1982 年 35 巻 5-6 号 p. 231-234
発行日: 1982年
公開日: 2010/03/19
ジャーナル フリーThe enhancing effects of lead acetate on the lethal and the bodyweight-decreasing activities of endotoxin in mice with different combinations of the administration routes. The effect of lead acetate on the lethality was shown by iv administration, but not by ip administration. The body-weight-decreasing activity of endotoxin was enhanced by ip administration of lead acetate but not by iv administration. In any case, the route of administration of endotoxin was not concerned with the enhancement by lead acetate.抄録全体を表示PDF形式でダウンロード (370K) -
GREGORY B. HEISEY, AKIRA SHIRAI, MICHAEL G. GROVES1982 年 35 巻 5-6 号 p. 235-238
発行日: 1982年
公開日: 2010/03/19
ジャーナル フリーThe effect of age on the susceptibility of ICR mice to lethal intraperitoneal (ip), Rickettsia tsutsugamushi infections was tested with five virulent strains -Karp, Kato, Gilliam, TA763, and TH1817- and three strains of reduced virulence-TA678, TA686, and TA716. Susceptibility differences were noted only in the ICR mice inoculated with two of the strains of reduced virulence, TA716 and TA678. With both strains, mice in the 12-weeks and younger age groups had lower death rates than did mice in the 21-weeks and older age groups. Also, CBA/CaJ mice of varying ages were inoculated intravenously with large doses of the Gilliam strain to determine the effect of age on susceptibility to acute death syndrome (ADS) . A progressive increase in ADS resistance was seen in the 4-, 8-, 12-, and 16-week-old age groups. This study indicates that the age of mice used to test the virulence of R. tsutsugamushi strains may be an important consideration, especially when testing the ip lethality of strains of reduced virulence.抄録全体を表示PDF形式でダウンロード (435K) -
三田村 弘, 亀山 邦夫, 安藤 芳明1982 年 35 巻 5-6 号 p. 239-242
発行日: 1982年
公開日: 2010/03/19
ジャーナル フリーConventionally raised suckling mice were given 107 spores of a strain of Clostridium botulinum type E. Most but not all infant mice aged 8 through 19 days at the time of administration died after developing symptoms typical of botulism. However, none of the infant mice challenged with the spores at dose levels lower than 106 spores/mouse developed illness.抄録全体を表示PDF形式でダウンロード (334K) -
BRAHMA D. PARASHAR, KARUMURU M. RAO1982 年 35 巻 5-6 号 p. 243-247
発行日: 1982年
公開日: 2010/03/19
ジャーナル フリーUnder laboratory conditions, snail Indoplanorbis exustus exhibited a strongly positive linear correlationship between duration of desiccation to mortality and body-weight loss and also body-weight loss to mortality. The adult stage of snail is highly resistant to desiccation, whereas the juvenile stage is highly susceptible. Reasons for decrease in susceptibility to desiccation with increase in shell diameter were suggested.抄録全体を表示PDF形式でダウンロード (375K) -
鈴木 映子, 松原 純子, 斎藤 学, 武藤 健, 中川 雅郎, 今泉 清1982 年 35 巻 5-6 号 p. 249-254
発行日: 1982年
公開日: 2010/03/19
ジャーナル フリーPDF形式でダウンロード (514K) -
AKIRA SHIRAI, JAMES C. COOLBAUGH, ELISIE GAN, TEIK CHYE CHAN, DAVID L. ...1982 年 35 巻 5-6 号 p. 255-259
発行日: 1982年
公開日: 2010/03/19
ジャーナル フリーPDF形式でダウンロード (426K)
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