Four children with neurological disorders were examined with a Picker Vista-MR imager using a 0.5 tesla (T) superconducting magnet operated at 0.256 T. We separated images into T
1 and T
2 weighted. Ti weighted images were obtained using inversion recovery (IR) sequences or spin echo (SE) sequences with short echo time (TE) and short repetition (TR) (TE: 40 msec, TR: 0.4 sec). T
2 weighted images had long TE and TR (TE: 80 msec, TR: 2.0 sec).
In a 6-month-old girl with congenital muscular dystrophy (Fukuyama type), there were bilateral symmetrical high signal intensities (T
2 weighted image) and low signal intensities (T
1 weighted images) in white matter. But IR coronal images showed symmetrical high signal intensities within the posterior limb of internal capsule, thalami and some part of corpus callosum.
In a 9-year-old girl with acute relapsing disseminated encephalomyelitis, lesions showed higher intensities than normal brain tissues on T
2 weighted images. However, lesions could not be identified on T1 weighted images, because lesions had the same signal intensities as the surrounding tissues.
In two children with tuberous sclerosis, T
2 weighted images disclosed numerous uncalcified nodules within the cortex and foramen Monro, although CT scan revealed no abnormalities in the same regions. On T
1 weighted images, we could not recognize the lesions at the margins of the brain and CSF by partial volume effects.
MRI is a sensitive method for detecting the lesions in the central nervous system. We emphasized that T
2 weighted images were useful for detection of lesions.
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