余ハ「コンゴーロート」ノ血液凝固促進作用ト綱状織内被細胞系統殊ニ肝臟及ビ脾臟トノ關係ヲ窺ハントシ,先ヅ對照實驗トシテ脾臟剔出犬ノ脾臟剔出後5時間迄,脾臟及ビ肝臟全剔出犬ノ死亡ニ至ル迄ノ血液凝固時間竝ニ凝固要素ヲ測定シ,次イデ1%「コンゴーロート」溶液對瓩0.2ccヲ正常犬,對照開腹術施行犬,肝臟全剔出犬,脾臟剔出犬,脾臟及ビ肝臟全剔出犬ニ靜脈注射シ,其ノ血液凝固時間及ビ凝固要素ヲ測定シ次ノ如キ成績ヲ得タリ。
(1) 正常犬ニ「コンゴーロート」注射ヲ施行スル時ハ注射後30分ヨリ既ニ著明ナル血液凝固時間促進ヲ示シ,其ノ促進ハ注射後2時間ニテ最高ニ達シ,其ノ効果ハ大略5時間繼續セリ。然シテ凝固時間促進時ニハ著明ナルFibrinogenノ増加ヲ認メタリ。
(2) 對照開腹術施行犬ニ於テ手術的影響アリト認メラルル時間ニ於テ「コンゴーロート」注射ヲ施行スル時モ,正常犬ノ「コンゴーロート」注射ノ場合ト殆ンド大差ナク血液凝固時間促進ヲ來セリ。
(3) 肝臟剔出犬ニ於テ「コンゴーロート」注射ヲ施行スル時ハ,輕度ノ凝固時間促進ヲ招來スレド,Fibrinogen量ノ増加ハ認メラレズ。
(4) 脾臟剔出犬ニ於テ脾臟剔出後5時間迄ノ血液凝固時間ノ變動ハ一定ノ規律ヲ有セザルモ,Fibrinogen及ビAntithrombinハ稍明瞭ナル減少ヲ示セリ。亦脾臓剔出犬ニ「コンゴーロート」注射ヲ施行スル時ハ血液凝固時間ノ促進ヲ來シ,Fibrinogen増加ヲ認ムレドモ,正常犬ノ場合ニ比シテ稍劣ル。
(5) 脾臟及ビ肝臟全剔出犬ハ肝臟全剔出犬ニ比シテ一般ニ手術後ノ生存時間短カク,其ノ血液凝固時間ノ遲延,Fibrinogenノ減少及ビAntithrombinノ増加等ハ後者ニ比シテ尚早期ヨリ認メラルルモ,其ノ凝固時間遲延度,Fibrinogen減少度,Antithrombin増加度ハ兩者ニ大ナル差異ナシ。亦此ノ脾臟及ビ肝臟全剔出犬ニ「コンゴーロート」注射ヲ施行スル時ハ,血液凝固時間促進及ビFibrinogen増加ヲ招來セズ。
以上ノ成績ヨリシテ次ノ如キ結論ヲ得タリ。
(1) 「コンゴーロート」溶液ノ靜脈内注射ハ肝臟及ビ脾臟ヲ刺戟シテ,Fibrinogenヲ血中ニ増加セシメ血液凝固時間ヲ促進セシム。之ハ「コンゴーロート」注射ガ綱状織内被細胞系統ヲ刺戟シ其ノ機能ヲ亢進セシムルニ因ルモノナラン。
(2) 「コンゴーロート」注射ノ血液凝固促進ニ及ボス効果ハ,正常犬,脾臟剔出犬,肝臟全剔出犬ノ順位ニシテ,脾臟及ビ肝臟全剔出犬ニ至リテハ全ク効果ナキモノト認ム。
(3) Fibrinogenノ主要生成臟器ハ肝臟及ビ脾臟ニシテ,兩者ノ中肝臟ハFibrinogenノ大部分ノ生成ニ,脾臟ハ其ノ一部生成ニ與ルモノト認メラル。
(4) 脾臟ハAntithrombinノ生成ニ關與ス。

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余ハ對照開腹術施行犬及ビ肝臟全剔出犬ニテ,前者ハ手術後31/2時間,後者ハ血流阻止後21/2時間迄ニ於テ「ウィッテ・ペプトン」(對kg. 0.3gm.)靜脈内注射ヲ施行シタルニ,其ノ血液ハ一度ハ凝固スルモ凝塊ハ後ニ完全ニ溶解スル現象,即チ纎維素溶解現象(Fibrinolyse)ノ出現甚ダ多キヲ觀察セリ。然シテ更ニ其ノ原因ヲ追究セントシ,Tillet & Garner法ノSchmidt變法ヲ用ヒテ實驗ヲ行ヒ,其ノ血漿中ニ纎維素溶解素(Fibrinolysin)ナル酵素的物質ノ異常的増生アル事ニ起因スルコトヲ知レリ。次イデ更ニGarner & Tilletノ「アルコホール」ニ依ル沈降法ヲ用ヒテ血漿中ノ纎維素溶解素ヲ分離精製セント企テシモ豫期セル結果ヲ得ザリキ。
亦正常犬血ニ於テモ其ノ凝塊ハ稀ニ僅カニ溶解スル事アルヲ以テ,正常犬血漿中ニモ纎維素溶解素ハ微量ニ存在スルモノトセリ。
然レ共一度溶解現象ヲ終了セシ血液凝塊ノ溶解液ノ血漿中ニ於テハ纎維素溶解素ハ消失セルモノノ如シ。
而シテ溶解素ノ異常的増生ト開腹手術ノ影響及ビ「ペプトン」注射トハ密接ナル關係ヲ有スレドモ,溶解素ノ増生ト肝臟脱落トハ直接的關係ナキモノト認メラル。

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The use of massage-and bath dates from ancient times, but the scientific, especially medical investigation concerning it seems to be of recent origin Accordingly, we find only few literatures of medical studies about the effects of sportmassage or bath on the carbohydrate and lipids metabolisms of human blood. Consequently, in the present work, the behaviours of blood cell counting, blood suger and lipid contents of many champions of Karate, rowing and bicycle by sportmassage (whole body massage lasted 45 minutes) after each game, of common healthy or sick (diabetes and spinal caries) persons by massage at quiet times, and, of common helthy persons by warm bath (water bath 42°C, air bath 50°C each for 20 minutes) were observed.
The results of these experiments were summarised as follows;
1) The increases of red cell number after games (Karate, rowing and bicycle) were further continued by sportmassage, while after the massage at quiet times the number increased only slightly. The increase after warm water or air bath was not striking.
2) White cell number that multiplied after games was reduced by the massage, on the contrary, the number at quiet times was increased by this. The number was also increased by warm bath and recovered after 1/2 hours rest.
3) The blood suger in both cases of after games and at quiet times always showed tendency to be decreased by the massage. After warm bath, particulary water bath, it decreased similarly.
4) Of blood lipids, the phospholipid contents which changed after games nearly recovered, especially in blood corpuscle, by the massage to the values before the games, but at quiet times only by the massage reduced. By warm bath also decreased greatly after 30 minutes' rest following water bath. The iodine number of phospholipid remained unaffected in all cases.
Free and bound cholesterol contents were almost constant in various conditions.
No definite influence of masssage after the gemes was indicated on the neutral fat contents, while they incresed after massage at quiet times and decreased after warm bath slightly. The iodine number of neutral fat never changed.
In total lipids contents of blood, especially of blood, corpuscle after games the recovering to the values before the games was quickened by massage, but at quiet times the contents were reduced by massage and bath.
5) Above described effects apparently suggest to indicate that sportmassage and warm bath stimulate the blood circulation and metabolisms of carbohydrate and lipids of blood, thus the recovery of weariness after exercise was quickened.

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