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Volume 13, Issue 1
Displaying 151-166 of 166 articles from this issue
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T. TSUJI, Y. OHE, K. IWABUCHI, T. TOGAWA, T. TAMURA, T. TOYOSHIMA, T. ...1984 Volume 13 Issue 1 Pages 535-538
Published: February 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSForehead (F) and sole (S) deep temperature (DT) of 50 patients with congenital heart diseases were measured during open heart surgery with deep body thermometer (Terumo Co., Coretemp). Mild hypothermia was applied by CPB. F·DT responded most quickly to the changes of perfusion temperature and S·DT, slowest. The lowest temperature of F·DT was lower than that of S·DT. Time delay and DT differences between transition point of F·DT and S·DT was observed in rewarming. Peripheral perfusion seemed very poor below 34°C of F·DT. CPB made S·DT response delayed through influencing autonomic nervous system.View full abstractDownload PDF (472K) -
M. KADOWAKI, Y. WADA, Y. SASAKI, S. SHIMADA, Y. KANKI, T. IWAMOTO, S. ...1984 Volume 13 Issue 1 Pages 539-542
Published: February 15, 1984
Released on J-STAGE: December 02, 2011
JOURNAL FREE ACCESSPostoperative brain damage in profound hypothermia have been reported extensively, and attributed to the disturbance of resional cerebral perfusion during hypothermia as one of the casations. In this experiment, the resional cerebral blood flow (CBF) of mongrel dog during the perfusion cooling with extracorporeal circulation (ECC) was measured by hydrogen gas clearance method. The mongrel dogs were cooled by pulsatile and nonpulsatile perfusion (pulsatile and nonpulsatile group). Both groups were cooled to an esophageal temperature of 20°C with the same perfusion rate (150ml/min/kg). In the pulsatile group, CBF under normothermic ECC scarcely decreased compared with physiological CBF before ECC. CBF under hypothermic ECC decreased compared with CBF under normothermic ECC in the both groups, but there was significant difference between two groups.View full abstractDownload PDF (2738K) -
[in Japanese]1984 Volume 13 Issue 1 Pages 543
Published: February 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSDownload PDF (171K) -
F. NOMURA, H. HIROSE, H. MATSUDA, S. OHTAKE, S. NAKANO, S. MAEDA, K. T ...1984 Volume 13 Issue 1 Pages 544-547
Published: February 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSGas transfer performance of Low Pressure Membrane (LPM-50) Oxygenator was evaluated using a testing and evaluation method which was previously reported from our laboratory.
It had such a good has transfer performance as Kolobow oxygenator. Practical operation indices were summarized as follows. As the practical operation index, optimum membrane index (OMI) was 0.5-1.5L/min/M2 and control index was between 0.4 and 0.7 when OMI was 0.5L/min/M2, between 0.8 and 1.2 when OMI 1.0L/min/M2, and over 1.0 when OMI 1.5L/min/M2.
According to these indices, clinical uses were performed in 26 adults patients and good results were obtained. As LPM-50 oxygenator uses a single pump and has a low blood side pressure drop like a bubble oxygenator, it is especially useful in using pulsatile pump and brain separated perfusion with deep hypothermic cardiopulmonary bypass.View full abstractDownload PDF (496K) -
M. YAMAGISHI, K. SOEJIMA, M. ENDO, A. HASHIMOTO, H. KOYANAGI, S. SUZUK ...1984 Volume 13 Issue 1 Pages 548-551
Published: February 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSA new low pressure drop membrane oxygenator (LPM/50) was used in 15 clinical cases of valvuler heart disease. In LPM/50, blood pathways formed by microporous polypropylene membrane are wide enough to gain a low blood side pressure drop, so it uses a single pump as a bubble oxygenator.
In clinical use, LPM/50 provided adequate O2 and CO2 transfer. PaO2 was 385±75mmHg (O2 100%), 371±105mmHg (O2 70%), and 263±42mmHg (O2 50%). PaCO2 was 35±4mmHg. The rate of increase of plasma free hemoglobin during cardio-pulmonary bypass was 0.33±0.7mg/dl/min. in LPM/50 group (n=9), which was significantly low compared to 0.58±0.20mg/dl/min. in another membrane oxygenator (Kolobow) group (n=6, P<0.025) and 0.70±0.29mg/dl/min. in a bubble oxygenator (BOS-10) group (n=6, P<0.010).
There was no tendency of decrease of platelet counts during cardiopulmonary bypass in LPM/50 group, while in another membrane oxygenator (Kolobow) group and a bubble oxygenator (BOS-10) group, platelet counts decreased. These results were satisfactory enough for clinical use both in O2 and CO2 transfer and in minimal blood trauma.View full abstractDownload PDF (2491K) -
N. AONO, M. UMEZU, T. TANAKA, Y. TAENAKA, T. NAKATANI, H. TAKANO, T. T ...1984 Volume 13 Issue 1 Pages 552-555
Published: February 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSThe increase of oxygen-blood flow ratio (V/Q) was corresponded well with the increase of both oxygen and carbon dioxide transfer rate as well. However, the increase of blood flow produced the decrease of both oxygen and carbon dioxide transfer rate. The gas exchange characteristics of LMP-50 membrane oxygenator appeares to be inferior to bubble oxygenator (BOS-10, Harvey 1500), however, the performances were proved to the best among 6 different type of membrane type oxygenator which were tested. Because of the possible for gravity drainage of this device, the circuit was simplified and the handling was found to be rather easy as the result. In a circumstance of high blood flow rate and low blood temprature, sufficient level of gravity is necessary because of the increase of resistance in the oxygenator.View full abstractDownload PDF (475K) -
K. MORITA, T. KOZUKUE, T. SASAKI, K. SUZUKI, T. ARAI1984 Volume 13 Issue 1 Pages 556-559
Published: February 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSWe have investigated 40 cases of cardiopulmonary bypass using IPMO, TMO and Shiley B. O. on changes in blood cell counts, plasma protein concentration, renal function and renin-aldosterone system.
The influence on peripheral blood cells in the IPMO group was almost similar to the data in the TMO group except for the influence on Leucocytes in spite of its pulse pressure.
In the case of the Shiley group hemolysis, a decrease of platelet counts and an elevation of Leucocytes counts appeared earlier during CPB compared to the other groups.
But changes in immunoglobulin, complements and fibrinogen were the same among the three groups.
In the renal function and P. R. A there was little difference among them, it was demonstrated that a pulse pressure obtained when the IPMO was used was not effective clinically.View full abstractDownload PDF (501K) -
-A comparison of CML oxygenator and Bubble oxygenator-K. KUDOH, M. UEDA, T. KONISHI, K. FUSE, Y. HOSODA1984 Volume 13 Issue 1 Pages 560-566
Published: February 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSThe Cobe Membrane Lung contains heat-exchanger, blood reservoir and membrane oxygenator in one compact body and has advantage in it's easiness of setting-up. In vitro experiments to measure it's efficiency of gas exchange, amount of hemolysis, rate of heat-exchange and rate of pressure-drop were performed with favorable results. Thirty-one AC-bypass cases using CML oxygenators were compared with fifty-nine AC-bypass cases using BUS-10S oxygenators in regard to hemolysis and amount of post-op chest tube drainage. Significant difference in the amount of hemolysis and post-op chest tube drainage were observed, namely 2.1mg/dl/hr in CML and 5.4mg/dl/hr in BOS-10S; 356±116.9ml in CML and 762±535.3ml in BUS-10S groups.View full abstractDownload PDF (796K) -
[in Japanese]1984 Volume 13 Issue 1 Pages 567
Published: February 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSDownload PDF (138K) -
H. MATSKURA, H. TAKEDA, S. UZAWA, T. GODA, M. SAKUMA, T. MASTUNAMI, K. ...1984 Volume 13 Issue 1 Pages 568-571
Published: February 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSThe new type hollow fiber oxygenator (Termo Capiox II) was used in 52 patients, and compared with Siley bubble oxygenator in 54 patients. The following results were obtained: 1) The former oxygenator showed adquate oxygenation in spite of relative low oxygen-blood flow rate, but we now use a device for supplying mixed gas (F1O20.5, gas-blood flow 1:1), because inadequate elimination of carbon dioxide was observed, 2) The oxygenator showd less hemolysis. 3) The oxygenator maintained adequate perfusion pressure and perfusion flow in spite of one pump system. 4) There is no problem with hollow Fiber oxygenator during perfusion.View full abstractDownload PDF (518K) -
J. NARUMI, K. SUMA, Y. TAKEUCHI, K. INOUE, K. SHIROMA, U. KOYAMA, S. N ...1984 Volume 13 Issue 1 Pages 572-575
Published: February 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSThe microporous polypropylene hollow fiber oxygenator with a built-in heat exchanger was used for open heart surgery in 162 patients. Gas exchange performances of the oxygenator were excellent and pressure drop was in an acceptable range.
Although heat exchange coefficient of the heat exchanger was excellent, there was time delay of blood temperature change in the arterial line, when the heat exchanger was situated in the venous line.
Time constant of blood temperature change in the arterial line was 1.5±0.3 times longer than that just after the heat exchanger.View full abstractDownload PDF (1004K) -
Y. ISHII, H. TANOI, [in Japanese], K. OHMORI, Y. NAKAOKA, H. SHINOHARA ...1984 Volume 13 Issue 1 Pages 576-578
Published: February 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSRecently severe heart diseases and open heart surgery for old men have increased. Therefore membrane oxygenator is ideal for these cases. Silicone hollow-fiber oxygenator (SHO), which we have developed, has an excellent capability and has a little effect on blood. We have improved SHO and reported the clinical application since 1979. Recently, we have developed a SHO equipped with a Brown Harrison heat exchanger and we have used it for 10 open heart surgery cases. We have compared it with the previous SHO. There was no significant difference between the new SHO and the old SHO in gas transfer, platelet counts and serum free hemoglobin. New SHO is compact and easy to use with an excellent capability.View full abstractDownload PDF (2171K) -
H. SAIGUSA, M. KAWAMURA, M. TANAKA, T. ABE, Y. IYOMASA1984 Volume 13 Issue 1 Pages 579-582
Published: February 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSMetabolic and hormonal changes during extracorporeal circulation (ECC) by membrane (Capiox 54) and bubble oxygenator (Sheily 100A) were studied. Ecc was accompanied with moderate hypothermia. Lactic acid and lactic acid/pyrubic acid were wore increased in the membrane oxygenator group than the bubble oxygenator group. On the other hand, epinephrine and norepinephrine increased in the bubble oxygenator as compared with the membrane oxygenator. There was no statistical difference between both groups in the cortisol and blood sigar. Significant increase of arterial oxygen teusion (PaO2) was observed in the membrane oxygenator group in this series. These results depend on the deterioation of peripheral circulation induced by high PaO2. So a divice aboiding high arterial oxygen teusion is necessary in the using of Capiox 54.View full abstractDownload PDF (367K) -
T. IMAZEKI, H. ARAI, M. YANO, S. TANABE, T. OKAMURA, H. NAKAHARA, J. A ...1984 Volume 13 Issue 1 Pages 583-585
Published: February 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSTokyo Medical and Dental University, Tokyo, Japan The polypropylene hollow fiber oxygenator was used for open heart surgery in 16 patients. Hematological data, PaO2 PaCO2 were within normal limits. The polypropylene hollow fiber oxygenator was significantly better in the data PaO2, PaCO2, O2/Q, than the bubble oxygenator and the TMO membranouss oxygenator.View full abstractDownload PDF (304K) -
-silicone hollow fiber and polypropylene hollow fiber membrane oxygenator-M. NASU, K. MIYAMURA, K. SHIKANO, I. YADA, S. SHOMURA, T. MORIMOTO, T. ...1984 Volume 13 Issue 1 Pages 586-588
Published: February 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESS24 hours veno- arterial bypass in dogs was underwent using silicone hollow fiber (SHMO) and polypropylene hollow fiber membrane oxygenator (PHMO) in order to evaluate gas exchange capacity and blood damage for both oxygenators, especially we measured the volume of transudate fluid through microporous membrane during ECMO using PHMO. Gas exchange capacity of SHMO was stable but one of PHMO decreased between 12 hours and 18 hours after bypass because of retention of transudate fluid. Platelet counts were preserved 84.7% of prebypass level at 24 hours after bypass in SHMO group and 51.3% in PHMO. Serum free hemoglobin concentration maintained less than 50mg/dl in both groups. In PHMO group, serum transudated through membrane since 8 to 13 hours after bypass and increased to 210ml/hr at the end of bypass. And then urine output decreased significantly. We had to transfuse blood and electrohte fluid. Therefor SHMO is the excelent oxygenator for long term ECMO with regard to maintaining homeostasis of living body.View full abstractDownload PDF (390K) -
[in Japanese]1984 Volume 13 Issue 1 Pages 589
Published: February 15, 1984
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSDownload PDF (120K)