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Volume 25, Issue 3
Displaying 51-53 of 53 articles from this issue
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Yoshio MISAWA, Ray C-J CHIU, Osamu KAMISAWA, Tsuguo HASEGAWA, Katsuo F ...1996 Volume 25 Issue 3 Pages 749-752
Published: June 15, 1996
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSDynamic Cardiomyoplasty is a new surgical intervention for patients with dilatedd cardiomyopathy, and clinical and hemodynamic improvement after operation has been proven. Not only systolic augmentation but girdling effect, sparing effect, and angiogenesis might be closely related to the postoperative improvement, contributing to a better remodeling of a failing heart. The girdling effect prevents a heart from becoming enlarged, and the sparing effect reduces the wall stress of the heart. Angiogenesis was recognized in the interface between a wrapped skeletal muscle and myocardium in our patient with ischemic cardiomyopathy. Current issues to be resolved in dynamic cardiomyoplasty are a long conditioning period of a wrapped skeletal muscle and sudden death after operation. This new operation does not require donor hearts, thus immunosuppresive agents are not administered postoperatively. In other words, dynamic cardiomyoplasty excludes rejection and opportunistic infections, which are serious complications in transplantation.View full abstractDownload PDF (2774K) -
K. NISHIHARA, T. TANGE, R. MATSUDA, H. SENO, A. YANAI, K. FUJII, J. TA ...1996 Volume 25 Issue 3 Pages 753-758
Published: June 15, 1996
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSExprimental evolutionary studies is proposed in this paper by means of trilateral research combining phylogenyontogeny, biomechanics, and molecular genetics. Through this new research method the correlation between inheritance and immune system is studied and a new concept for immunology as cytological digestion system is also proposed. Combining biomechanical stimuli with biomaterials in animal, experimental evolutionary study was carried out. Hybrid type artificial organ inducing hemopoietic bone marrow tissue could be successfully developed using hydroxyapatite chamber not only in mammals but sharks, which is relict of archetype without bone marrow tissue in internal skeletons. Cementoblasts could be also induced biomechanically. In these new methods, in vivo culture of liver and pancreas in hydroxyapatite chamber was carried out.View full abstractDownload PDF (10689K) -
S. KYO, K. UEDA, N. MIYAMAOTO, T. MOTOYAMA, Y. YOKOTE, H. ASANO, M. OG ...1996 Volume 25 Issue 3 Pages 759-764
Published: June 15, 1996
Released on J-STAGE: October 07, 2011
JOURNAL FREE ACCESSWe implanted Left ventricular assist systems on 4 patients with terminal stage of dilative cardiomyopathy (DCM) in the past 4 years. The patients were all male with average age of 47 year-old. The average of the left ventricular ejection fraction was 12.5% and that of cardiothoracic ratio was 69.3% before LVAS implantation. NCVC-LVAS was implanted on 3 patients and TCI -LVAS was implanted on one patient. One patient who required cardiac resuscitation prior to VAS implantation could not recover his consciousness and died on 14 postoperative days (POD). 3 patients were separated from respirator within 2 days and recovery of renal function was obtained within 2 weeks and that of hepatic function within 4weeks after LVAS implantation. Recovery of LV function was not obtained in 2 patients who were supported with NCVC-LVAS and died on 43 POD and 44 POD. A remarkable recovery of LV functional was obtained in the patient with TCI-LVAS, however, an accidental sudden bleeding occurred on 26 POD and died on 40 POD. Although LVAS support was very effective for the terminal stage of DCM, it is required to increase our clinical experience to maintain good circulatory and general conditions avoiding complications for more successful results.View full abstractDownload PDF (860K)