All issues
Volume 40 (1988)
- Issue 6 Pages 711-
- Issue 5 Pages 615-
- Issue 4 Pages 437-
- Issue 3 Pages 291-
- Issue 2 Pages 133-
- Issue 1 Pages 1-
Volume 40, Issue 6
Displaying 1-4 of 4 articles from this issue
- |<
- <
- 1
- >
- >|
-
Koji WAKUDA, Yoshiki TAKAHASHI, Yoshihiko HAYASHI, Tatsuo SUDO, Kazuhi ...1988 Volume 40 Issue 6 Pages 711-718
Published: November 01, 1988
Released on J-STAGE: July 05, 2011
JOURNAL FREE ACCESSA 26-year-old primiparous woman with systemic lupus erythematosus (SLE) was referred to our clinic at 5 weeks of gestation. She was in an active phase of SLE with malar and discoid rash, leg edema and fever. Prednisolone had been given orally 10mg/day before the pregnancy, and repeated exacerbations and remissions of SLE occurred until the second trimester. At 18 weeks of gestation, a sudden exacerbation of SLE was observed. The dose of prednisolone was increased and she was admitted. From 22 weeks of gestation, she was treated with increased dose of prednisolone and/or betamethasone depending on the activity of SLE. Preeclampsia developed at 22 weeks of gestation, and she was treated with labetalol hydrochloride. At 32 weeks and 2 days of gestation, the amniotic fluid shake test became positive, and a non reactive pattern and recurrent late decelerations were found on non stress FHR monitoring. She was delivered by cesarean section. The 1, 002 grm. male newborn infant had no congenital malformations or respiratory distress syndrome.
SLE is one of the most severe risk factors for both mother and infant. Exacerbation of SLE, nephropathy, and preeclampsia are most common complications. Abortion, stillbirth, feto-placental insufficiency and congenital A-V block of the infant are also observed in this condition.
In our judgement, the most important points in the management of a pregnancy in a woman with active SLE are : (1) to know whether or not the patient is in an active phase, (2) to control the medication and dosage of corticosteroids, according to the degree of exacerbation or remission of SLE, (3) to induce delivery at an appropriate time with sufficient fetal maturity. It is also most important to distinguish between nephropathy of SLE and preeclampsia. Skin lesions, serum complement levels and the erythrocyte sedimentation are useful in the differential diagnosis between the two diseases.View full abstractDownload PDF (6297K) -
Ichiro YAMADE, Yoshiki TAKAHASHI, Kazuhiko KASAHARA, Toshio TENZAKI, A ...1988 Volume 40 Issue 6 Pages 719-727
Published: November 01, 1988
Released on J-STAGE: July 05, 2011
JOURNAL FREE ACCESSThis is a retrospective study of 48 patients with ovarian cancer treated at the Shiga University of Medical Science between January 1979 and December 1987. The standard operative procedure was bilateral salpingooophorectomies, abdominal total hysterectomy and partial omentectomy. First line chemotherapy was FAM (T), CAP (F), or QF for epithelial ovarian carcinoma, and VAC or VAQ for germ cell ovarian cancer. Second line chemotherapy after development of the resistance to CAP (F) was PCE or VPP.
The five-year survival rates for primary ovarian cancer were 80.8 % for stage I, 41.1% for stage III, and 22.5 % for stage IV. For the stage I and II primary ovarian cancers, the five-year survival rate was 83.3% with CAP (F) chemotherapy, and 100% with FAM (T). No significant difference was found between CAP (F) and FAM (T). For stage III and IV primary ovarian cancers, the two-year survival rates was 80.0% with CAP (F), and with 0.0% with FAM (T) a significant difference.
In ten patients, a second-look laparotomy/laparoscopy after the standard operation and adjuvant chemotherapy was performed as a part of the management protocol. Six patients with cancer positive results confirmed by a second-look laparotomy/laparoscopy had a median duration of only 6.2 months of remission. One of the six patients died, and three patients had recurrent tumors. Four patients with cancer negative results confirmed by second-look laparotomy/laparoscopy had a median duration of 24 months of remission. All four patients are alive and show no evidence of disease.
In all cases of recurrent or uncontrolled tumors after first line chemotherapy, There was no or very poor response to second line chemotherapy.
The treatment of stage I and II ovarian cancer and acquired drug resistance to first line chemotherapy must be leaved for a future study.View full abstractDownload PDF (4634K) -
Kazuko MURATA, Akira YAMAMOTO, Hiromu ONDA, Yuji FUJINO1988 Volume 40 Issue 6 Pages 729-732
Published: November 01, 1988
Released on J-STAGE: December 05, 2011
JOURNAL FREE ACCESSA rudimentary horn of a bicornuate uterus is a rare uterine anomaly.
It occurs as a result of arrested development of one of tee Müllerian ducts and subsequent incomplete fusion with the opposite side.
Furthermore, pregnancy in the horn is rare, with an estimated incidence of 1 in 140, 000 deliveries. Pregnancy occurred in the rudimentary horn of a bicornuate uterus in a 23-year-old woman who was followed at our clinic for her uterine malformation.
The abnormal pregnancy was diagnosed early in gestation by ultrasonography before it ruptured.View full abstractDownload PDF (4576K) -
Masahide SHIOTANI, Ichirou TAKAI, Hiroshi OZASA, Takahide MORI1988 Volume 40 Issue 6 Pages 733-735
Published: November 01, 1988
Released on J-STAGE: July 05, 2011
JOURNAL FREE ACCESSTumors of the mesentery are sometimes mistaken for ovarial ones. This report deals with a case of 25 year old woman with a benign tumor of the mesentery.
She was admitted to our hospital with complaint of occasional abdominal pain. Physical examination revealed a new born head sized, tense elastic and movable tumor occupying the pelvic cavity. Peripheral blood analysis, serum biochemistry and tumor marker data showed no abnormality.
The tumor was suspected to be a ovarian endometrial cyst by ultrasonography, X-CT and MR-CT. Laparotomy revealed a cyst of the mesentery of the small intestine. Histologically, the tumor proved to be a benign cyst.
A reviw of the literatures is added.View full abstractDownload PDF (2658K)
- |<
- <
- 1
- >
- >|