A 27-year-old woman (gravida 3) complained of slight vaginal bleeding after amenorrhea. A local physician found her urinary hCG level to be 1, 600, 000IU/l. He performed a D & C but found only endometrial membrane with decidual. change. Ultrasonogram showed an enlarged ovary, and she was referred to our clinic on February 19, 1986. The following examinations were performed : urinary hCG, pelvic ultrasonography, CT scanning and pelvic angiography. From the results examined choriocarcinoma of the ovary was highly suspected. On March 4, abdominal simple total hysterectomy and bilateral salpingo-oophorectomy were performed. The histopathological diagnosis was choriocarcinoma without any other types of tumor cells.
After five courses of postoperative chemotherapy using methotrexate and actinomycin-D, her serum hCG level came down within normal range, then she was discharged on July 30, 1986. Follow-up examinations for 8 years have shown no evidence of recurrence. [Adv Obstet Gynecol 46 (3); 287-292, 1994 (H6.5)]
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