Chemical examination of the fresh rhizomes of
Tupistra wattii H
OOK. f. led to the isolation of three new steroidal saponins, wattoside G (1), H (2), and I (3), together with one known steroidal saponin, (25
S)-1β,3β,4β-trihydroxyspirotan-5β-yl-
O-β-
D-glucopyranoside (4). The structures of 1—3 were established to be (25
R)-1β,2β,3β,5β-tetrahydroxyspirostan-4β-yl-
O-β-
D-xylopyranoside (1), (24
S,25
S)-24-[(β-
D-glucopyranosyl)oxy]-1β,2β,3β,4β,5β,7β-hexahydroxyspirostan-6-one (2), and (24
S,25
S)-1β,3β-dihydroxy-5β-spirostan-24-yl-
O-β-
D-glucopyranosyl-(1→6)-β-
D-glucopyranoside (3) on the basis of detailed analyses of physical, chemical, and spectral data. The isolated compounds were evaluated for cytotoxic activity against the cancer cell line K562
in vitro.
抄録全体を表示