Skindex16 is one of the most frequently used questionnaires to evaluate the impact of dermatological diseases on patientsʼ QOL. This study aimed to assess the influences of age, gender, and disease on Skindex16 scores. We measured the QOL of 1,202 new Japanese outpatients in the Department of Dermatology, Kyushu University Hospital, using the Japanese version of Skindex16. We found that women had a worse QOL, especially on the emotion scale, than did men, and that younger patients had a poorer QOL than older ones. The QOL of patients with eczema, urticaria, keratoses, and skin appendage diseases was significantly more impaired than that of patients with other diseases.
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