We studied the efficacy of a 585 nm pulsed dye laser for treating 16 cases of psoriasis vulgaris. Phototherapy, including PUVA and narrow-band UVB therapies, are considered as the second line for treating psoriasis vulgaris when the lesions are resistant to topical treatments such as steroid or vitamin D
3. Because of photocarcinogenesis, a new method of therapy for psoriasis that targets only the lesional area has become a goal recently. There are some reports from foreign countries on the efficacy of 585 nm pulsed dye laser for psoriasis. Sixteen Japanese patients with refractory psoriasis vulgaris were enrolled to this study. Seven patients (44%) showed significant clinical improvement and two of them remained in remission for more than two years. The system appeared to be more effective in the treatment of plaques of the trunk than of those of the extremities. No severe adverse effects of laser irradiation on the plaques were recorded. Based on the evidence that the refractory psoriasis vulgaris responded well to 585 nm pulsed dye laser, we propose that 585 nm pulsed dye laser can be recommended as an alternative therapy for psoriasis vulgaris.
View full abstract