We examined the clinical data from 61 cases of sebaceous carcinoma diagnosed at the Sapporo Institute for Dermatopathology from May 2001 to August 2006. They included male 27 cases and 34 female cases. The average age at resection was 74.0±12.1 year-old. In 21 cases (35.2%), the lesions were located on eyelid; in 25 cases (35.2%), on head and neck regions other than the eyelids, and, in 14 cases (24.1%), on regions other than the head and neck. Clinically, the lesions on the eyelids were most frequently diagnosed as malignant neoplasms, but those on extra-ocular regions were diagnosed as benign neoplasms. About half of the lesions on the eyelids were resected by ophthalmologists, whereas over half of the extra-ocular cases were resected by dermatologists. We compared the number of cases of sebaceous carcinoma with those of other cutaneous malignant neoplasms diagnosed at our Institute during the same period. The number of basal cell carcinoma cases was 30 times, that of squamous cell carcinoma cases was 15 times, and that of malignant melanoma and Extramammary Paget’s disease was three times higher than those of sebaceous carcinoma, although the number of sweat gland carcinomas was lower. The cases of sebaceoma were three times more frequent than those of sebaceous carcinoma; in contrast, those of sebaceous adenoma were less than half as frequent.
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