The Japanese Journal of Dermatology
Online ISSN : 1346-8146
Print ISSN : 0021-499X
ISSN-L : 0021-499X
Volume 132, Issue 1
Displaying 1-10 of 10 articles from this issue
Committee Report
Seminar for Medical Education
Original Articles
  • Yasuyuki Yamaguchi, Emi Inamura, Misako Yamaga, Kazuhiko Furuya
    2022 Volume 132 Issue 1 Pages 49-55
    Published: January 20, 2022
    Released on J-STAGE: January 20, 2022

    In Southern Hokkaido, more than 80% of dermatology patients who receive biologics indicated for psoriasis visit the Department of Dermatology at Hakodate General Central Hospital. We investigated the residential addresses and the cost burdens of these patients in detail. To resolve regional issues, it is necessary to utilize information and communications technology and to secure dermatologist resources. We sincerely encourage dermatologists in urban areas to take a greater interest in community medicine.

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Case Reports
  • Naoko Kubo, Akiko Kishi, Mio Fukui, Sayuri Miyake, Aki Yoshida, Nobuka ...
    2022 Volume 132 Issue 1 Pages 57-67
    Published: January 20, 2022
    Released on J-STAGE: January 20, 2022

    We experienced three cases of onychomatricoma with a the chief complaint of thickened nail. Case 1 was a 59-year-old female whose right thumb nail had been thickened for 13 years, with a width of 4 mm at the lamellar tip. Case 2 was a 48-year-old female whose right index fingernail had been thickened for 10 years; the width was 8 mm. The tip of the nail resembled a sieve. Case 3 was a 47-year-old male whose left middle fingernail had been thickened like a pillar for 4 years; the width was 8 mm. The tip of the nail a brain-like appearance.

    All three cases had common features; the entire nail was thickened, the nail had a pillar-like appearance, and there was pain during nail cutting. Dermoscopic findings showed yellow-whitish lines, brown lines, hemorrhage-like splinters, and longitudinal grooves. Magnetic resonance imaging of Case 2 and 3 revealed crest-shaped tumors with low density on T1-weighted and high density on T2-weighted and diffuse images.

    Pathological examinations revealed continuously growing papillary tumors with sieve-like cavities extending form the nail matrix to the tip. The tumors consisted of spindle cells with nuclei of various sizes, accompanied by giant cells. In addition, collagen fibers proliferated in the interstitial tissue.

    The above findings led to the diagnosis of onychomatricoma in all three cases. They all underwent surgical treatment, and no recurrence has been noted. On the basis of our experience, we conclude that magnetic resonance imaging demonstrating a saw-tooth like appearance is very characteristic of onychomatrichoma and helps to diagnose it. This should be an important parameter assessed in all such patients to establish the diagnosis of onychomatrichoma.

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Quick Reports
  • Yuki Kobayashi, Takeya Adachi, Hiroki Arakawa, Toyoko Inazumi
    2022 Volume 132 Issue 1 Pages 69-73
    Published: January 20, 2022
    Released on J-STAGE: January 20, 2022

    A 77-year-old man was referred to our department with eruptions over his entire body, which started two days after the second dose of vaccination for SARS-CoV-2 (Comirnaty®). At the first visit three weeks after the vaccination, annular edematous erythema had spread and coalesced the trunk and extremities without itchiness; some of it presented target-like lesions. Based on the clinical and pathological findings, we diagnosed this case as erythema multiforme after the Comirnaty® vaccination. There have been a few reports of erythema multiforme after vaccination for SARS-CoV-2, and similar cases are anticipated to emerge with the increase in the number of vaccinations and the start of a third dose for SARS-CoV-2. We here report this case with the result of lymphocytic transformation test of Comirnaty® with healthy controls with or without vaccination and summarize the past literature reports of erythema multiforme following vaccination for SARS-CoV-2.

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