We reviewed 75 cases (60 patients) infected with human immuno-deficiency virus (HIV) and/or syphilis who were treated in the Department of Dermatology and Laboratory Medicine at Tokyo Medical University Hospital between September of 2005 and October of 2008. Thirteen of the reported patients had been infected with syphilis twice or more. During the same period, 30 patients were infected with syphilis alone and received treatment. The patients infected only with syphilis were frequently in their forties and fifties; those with both HIV and syphilis were all males in their thirties and forties. Approximately half of the cases were of asymptomatic syphilis: the other half of the patients had symptomatic syphilis, with the majority of cases at the secondary, rather than the primary, stage. The CD4
+ lymphocyte count at the time of the diagnosis of syphilis varied and did not cluster in the lower values. The patients were treated with antibiotics such as amoxicillin, and all were cured. Among these cases, 51 were treated for less than one month using the normal dosage of antibiotics. Eight patients were found to be positive for HIV at the time they were diagnosed with syphilis.
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