The Japanese Journal of Dermatology
Online ISSN : 1346-8146
Print ISSN : 0021-499X
ISSN-L : 0021-499X
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Volume 132, Issue 3
Displaying 1-7 of 7 articles from this issue
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Seminar for Medical Education
Original Articles
  • Necrotizing Granulomatous Skin Disorder Caused by Accidental Injection of Oil Adjuvanted Chicken Vaccine Successfully Treated with Systemic Steroid Therapy
    Michiko Hasegawa, Ryuichi Saito, Ayumi Horiuchi, Atsushi Tamura
    2022 Volume 132 Issue 3 Pages 479-486
    Published: March 20, 2022
    Released on J-STAGE: March 22, 2022
    DOIhttps://doi.org/10.14924/dermatol.132.479
    JOURNAL RESTRICTED ACCESS
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    Although livestock farmers often suffer from accidental needle sticking while vaccinating animals, there are few reports describing the serious morbidities caused by animal vaccines. We report a 44-year-old man who accidentally injected oil adjuvant vaccine into his left palm during vaccination of chickens. The initial cellulitis-like reaction, presenting as redness and swelling of the affected limb, was followed by the progressive development of necrosis and ulceration of the palm. Histopathological examination of a biopsy specimen showed intense neutrophilic infiltration and granulomatous inflammation surrounding empty round spaces. From these results, we diagnosed a severe granulomatous inflammation caused by injected oil adjuvant vaccine. We were unable to remove a sufficient volume of injected vaccine due to anatomical complexity of the hand, so oral corticosteroid was administered to suppress the inflammatory reaction. Shortly after the initiation of steroid, the wound began to improve and finally healed. There have been few reports of systemic steroid therapy for accidental needlestick injuries containing oil adjuvant vaccine. Systemic steroid can be useful in the management of accidental injection of oil adjuvant vaccine, especially when sufficient surgical debridement is impossible in the early stages.

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Quick Reports
  • Herpes Zoster after COVID-19 Vaccination: Report of 8 Cases
    Shunsuke Imai, Yosuke Shimizu, Kenji Yoshida, Akira Ishiko
    2022 Volume 132 Issue 3 Pages 487-490
    Published: March 20, 2022
    Released on J-STAGE: March 22, 2022
    DOIhttps://doi.org/10.14924/dermatol.132.487
    JOURNAL RESTRICTED ACCESS
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    Many cases of Herpes Zoster after countries began distributing COVID-19 vaccines; however, none have been reported in Japan. In this study, eight cases of Herpes Zoster were detected among the innoculated with Phizer/Moderna COVID-19 vaccine. The mean age of the patient was 66.5 years, the male to female ratio was 1: 3, and 37.5% of the cases occurred between the first and second doses of the COVID-19 vaccine. The average number of days between vaccination and symptom onset was 8.75 days. The total number of Herpes Zoster patients increased from that of the previous year. When diagnosing Herpes Zoster during the COVID-19 epidemic, recording the date of COVID-19 vaccination and describing the symptoms will make it possible to conduct retrospective survey, so we prepared this preliminary report for dermatologists.

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