Journal of the Society of Powder Technology, Japan
Online ISSN : 1883-7239
Print ISSN : 0386-6157
ISSN-L : 0386-6157
Volume 57, Issue 10
Displaying 1-4 of 4 articles from this issue
Original Paper
  • Yoshitaka Kataoka, Kozo Yokota
    Article type: Original Paper
    2020 Volume 57 Issue 10 Pages 520-525
    Published: October 10, 2020
    Released on J-STAGE: December 09, 2020
    JOURNAL FREE ACCESS

    Material extrusion is an additive manufacturing process that generates a three-dimensional molded product via extrusion and lamination of a plastic material. In this study, we prepared zirconia filaments, which were composites of 3Y-ZrO2 powder and thermoplastic resins. Then, we investigated the influence of the filament fluidity and molding conditions on the voids generated at the bonded interface due to poor bonding of the extruded materials. Using a filament excelling in fluidity reduced the nozzle temperature, and molding could be carried out with reduced combustion of the binder resin. Hence, the void diameters of the molded bodies were reduced to 10 μm or lesser with the nozzle temperature of 138°C and layer thickness of 100 μm, and 97–98% relative densities of the sintered bodies were indicated.

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Short Communication
Reviews: Frontier Research Series
  • Shin-ichiro Kimura
    Article type: Review: Frontier Research Series
    2020 Volume 57 Issue 10 Pages 530-535
    Published: October 10, 2020
    Released on J-STAGE: December 09, 2020
    JOURNAL RESTRICTED ACCESS

    In pharmaceutical field, technology for manufacturing fine globular granules with a narrow size of particle distribution (100–200 μm) are crucially important in enhancing patient adherence and controlling drug release from functional granules, e.g., sustained release or taste-masking granules. A unique multi-functional rotor processor, “Granurex®” (GX, Freund, Japan), facilitate manufacturing the fine globular granules. In this study, we examined the relationships between operational conditions of the multi-functional rotor processor and the physical characteristics of the obtained granules, and optimized the manufacturing conditions for producing fine globular granules. In addition, we developed highly drug-loaded fine globular granules which composed of almost drug substance (>97%). We believe fundamental information obtained in this study will be important for the development of processes for the facile manufacture of fine globular granules of various drugs.

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Fundamentals of Powder Technology, 2nd Edition
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