巻号一覧
34 巻, 5 号
選択された号の論文の16件中1～16を表示しています
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浅井 隆善, 伊藤 道博, 脇田 久, 中島 燿子, 比留間 潔, 王 伯銘, 伊藤 国明, 吉田 尚, Isao Komori1988 年 34 巻 5 号 p. 505-512
発行日: 1988年
公開日: 2010/03/12
ジャーナル フリーThe A or B-glycosyl transferases of hematological diseases showed low activities in the majority of malignant diseases, and their activities became to normal during recovery and remission of the disease. In the cases of leukemia accompanied with A or B-red blood cell type changes, the glycosyl transferases were also low. There was one exception having a loss of A-red blood cell antigen with normal level of A-transferase. These findings suggest that there are other factors which cause red blood type change. For example; H-transferase decrement, abnormal proliferation of erythrobasts in addition to A or B-transferase decrement.抄録全体を表示PDF形式でダウンロード (4622K) -
妊娠中と分娩後のRhIG使用中村 幸夫, 齋藤 良治1988 年 34 巻 5 号 p. 513-516
発行日: 1988年
公開日: 2010/03/12
ジャーナル フリーThe first Japanese survey of the administration of Rho (D) immune globulin (RhIG) during antepartum and postpartum period is reported. RhIG were injected to 24 Rho (D)-negative pregnant women (total number of 32 pregnancies) at the most adequate period at Hirosaki University Hospital between 1984 and 1988. Among these groups, no Rho (D)-negative woman was sensitized. Abnormal findings have not been found in these newborn babies.抄録全体を表示PDF形式でダウンロード (428K) -
吉田 久博, 山下 紀美子, 伊藤 和彦, 神谷 晃1988 年 34 巻 5 号 p. 517-520
発行日: 1988年
公開日: 2010/03/12
ジャーナル フリーTo clarify reaction specificity of screening kits to detect anti-HN antibodies, we surveyed the antibodies in sera from hospitalized patients. Antibodies were detected in 66 (2.4%) of 2, 767 patients using the gelatine particle agglutination (PA) method. All of these positive sera were also positive with the Western blot method but not with the enzyme immunoassay (EIA) method. The epidemiological investigation was performed to elucidate why they had anti-HIV antibodies. Sixty five of the 66 patients positive for the antibody were administered intravenous immunoglobulin preparations (WIG) within one moth before the screening test. These results indicate that the PA method is superior to ETA method for detection of anti-HIV antibodies.抄録全体を表示PDF形式でダウンロード (481K) -
富沢 修一1988 年 34 巻 5 号 p. 521-525
発行日: 1988年
公開日: 2010/03/12
ジャーナル フリーInfection and pneumonia were serious complications of plasmapheresis. This risks were due in part from decrease of IgG subclasses. Thus, the measurements of IgG subclasses were made before and after plasmapheresis. An increase of IgG subclass levels was measured after treatment with 50mg/kg intravenous immunoglobulin preparation, which was given after 24 hours of plasmapheresis.
After 8 times of immunoadsorbent plasmapheresis, IgG1, 2, 4 decreased 90% and IgG3, 50% of pre-therapy. On the other hand, IgG1, 2, 3, 4 revealed a 60% reduction after 12 times of plasmapheresis, which 3 liters of plasma were replaced with 5% albumin-Hartmann solution. The level of IgG2 occasionally showed below 10mg/dl after replacement of 5% albumin-Hartamann solution.
Three different preparations of immunoglobulin (1-immunoglobulin treated with polyethylenglycol, 2-immunoglobulin treated with trace of pepsin in pH 4, and 3-immunoglobulin treated with sulfonation) were used to increase the level of IgG subclasses and their results were compared one each other. The increase of IgG 1, 2, 3, 4 was more pronounced after infusion of immunoglobulin treated polyethyleneglycol and trace of pepsin in pH 4 than infusion of immunoglobulin treated with sulfonation. However, in all conditions, after 1 week of albumin replaced plasmapheresis with infusion of immunoglobulin preparation were showed low levels of IgG subclasses.
It suggested that infusion of immunoglobulin preparation after albumin repalced plasmapheresis was necessary more than 50mg/kg dose. And, the check of IgG subclass was important after plasmaphersis.抄録全体を表示PDF形式でダウンロード (679K) -
P. Azar, S. Ogawa, S. Takimura, T. Yasuda, S. Yahara, H. Saji, T. Hoso ...1988 年 34 巻 5 号 p. 526-529
発行日: 1988年
公開日: 2010/03/12
ジャーナル フリーIn order to assess the feasibility of using a type and screen procedure in Kyoto, our laboratory did a retrospective study of 31, 490 crossmatches performed on 4, 276 patient samples. This included analysis of 672 patients who had positive antibody histories, and the distribution of the antibody specificities they developed. This study also reviewed a single (0.03%) case in which a patient with no history of antibody problems, and negative antibody screening, had an incompatible crossmatch. We also reviewed 11 (2.42%) cases of patients with histories of positive antibody screenings in which the current sample was nonreactive but the crossmatch was incompatible.
We have concluded that patient safety would not be at risk if certain essential guidelines are met when adopting a type and screen procedure.抄録全体を表示PDF形式でダウンロード (427K) -
小松 文夫, 笹川 滋1988 年 34 巻 5 号 p. 530-536
発行日: 1988年
公開日: 2010/03/12
ジャーナル フリーThe dialyzable leukocyte extracts (DLE) may have some effects in vivo, however, the effects of the DLE on lymphocytes were poorly understood, because the crude type of the DLE inhibits the lymphocyte blastformation in vitro. It has not been elucidated whether a substance involved in the DLE may enhance the blastformation or not. In this study, we measured intra-cellular ATP levels of lymphocytes after treating with the DLE or DLE fractions, and found that a fraction of the DLE increased the ATP levels of PHA-stimulated lymphocytes. In this fraction, inosine was involved. Inosine increased the ATP levels of lymphocytes and enhanced the blastformation. It is considered that when DLE show some effects on lymphocytes, inosine involved in the DLE may show important effects.抄録全体を表示PDF形式でダウンロード (762K) -
丸山 恵美子, 梅嶋 朱美, 斎藤 由美, 照屋 純1988 年 34 巻 5 号 p. 537-539
発行日: 1988年
公開日: 2010/03/12
ジャーナル フリーIn 1946, Callender et al. first reported Cw antigen and the corresponding antibody in Rh system. We found one case of anti-Cw, which is very rare in Japanese, although not so rare among white people, in a 69-year-old male patient with carcinoma of the bile duct. The patient had been transfused many times during the three months before anti-Cw was detected, but never prior to that. The titers of the antibody in saline method were 128, 16 and 16 at 37°C, 20°C, and 4°C respectively, 2, 000 by albumin method, and moreover 256 by bromelin method. It was not detectable by indirect antiglobulin test. This antibody was caused by unknown origin. Because Cw antigen is extremely rare in Japanese, so it is easy to obtain compatible blood for a patient with the anti-Cw.抄録全体を表示PDF形式でダウンロード (414K) -
武部 道和, 坪倉 兌雄1988 年 34 巻 5 号 p. 540-545
発行日: 1988年
公開日: 2010/03/12
ジャーナル フリーPatients who have antileukocyte antibody production should be transfused with Leukocyte-Poor Red Blood Cells to prevent non-hemolytic febrile transfusion reactions.
We prepared Leukocyte-Poor Red Blood Cells by four kinds of leukocyte removal filters in accordance with the Technical Manual of the Japanese Red Cross Society and have discussed respective functions of the filters.
The removal of Leukocytes, removal of platelets and the recovery of erythrocytes after filtration were as follows: Imugard IG-400Y filtration were 98.5±0.7%, 68.1±9.7%, 95.2±1.6%, respectively, Erypur filtration were 96.3±1.5%, 89.9±5.7%, 85.3±3.0%, respectively, Miropore filtration were 91.2±2.3%, 85.0±3.1%, 95.0±1.7%, respectively, Sepacell filtration were 97.7±1.1%, 94.6±2.2%, 97.4±1.6%, respectively.
No significant changes of erythrocytes were observed after filtration by four kinds of filters with respect to ATP content, 2, 3-DPG content and osmotic resistance value of erythrocytes.抄録全体を表示PDF形式でダウンロード (741K) -
永峰 啓丞, 青地 寛, 林 悟, 押田 眞知子, 倉田 義之1988 年 34 巻 5 号 p. 546-550
発行日: 1988年
公開日: 2010/03/12
ジャーナル フリーAn ELISA using micro-plates coated with red cell ghosts was developed for analysis of red cell antibodies. Red cells were coated to plates by poly-L-lysine and were converted into ghosts by lysis with a hypotonic phosphate buffer.
This assay was quantitative, objective and sensitive compared with indirect antiglobulin test, and was easy to perform compared with ELISA of tube method using red cell suspensions.抄録全体を表示PDF形式でダウンロード (589K) -
柴 雅之, 笹川 滋, 小方 英二, 清水 勝1988 年 34 巻 5 号 p. 551-557
発行日: 1988年
公開日: 2010/03/12
ジャーナル フリーPlasma and leukocyte poor red cell concentrates were stored in a new additive solution containing mannitol, citrate, phosphate, adenine and ascorbyl-2-phosphate for 6 weeks. The additive solution, MAAP-2 showed the best results.
The 24-hour autologus post-transfusion survival of 51Cr-labeled red cell was 95.1% and 89.3% for 3 and 6 weeks storage, respectively.
After 6-week stroage, ATP and 2, 3-DPG levels were 2.96μmole/gHb and 7.47μmol/gHb, respectively. Futhermore, the stored red cell shapes were ratained discoid and hemolysis decreased.
This solution enabled to provide an excellent red cell product with a long shelf life and with a normal oxygen affinity.抄録全体を表示PDF形式でダウンロード (2456K) -
血液製剤医薬品情報及び至適輸血量情報の病棟検索システムの開発吉田 久博, 山下 紀美子, 伊藤 和彦, 神谷 晃1988 年 34 巻 5 号 p. 558-563
発行日: 1988年
公開日: 2010/03/12
ジャーナル フリーA computer reference system of drug information and optimum transfusion volume of blood products was developed to promote their effective use. The programs were written in MUMPS language. The former reference system was utilized for referring indications and effects, ingredient or chemical entity, storage condition, expiration period, administration and dosage, remarks, contents, medical fee, and official name of each product. The latter was utilized for calculating transfusion volume to be necessary to increase patient's blood component level or for predicting peripheral blood level after products were transfused. As the information can be quickly accessed from the terminal computers at our hospital, our system is very effective to promote optimum use of blood products.抄録全体を表示PDF形式でダウンロード (621K) -
吉田 久博, 山下 紀美子, 伊藤 和彦1988 年 34 巻 5 号 p. 564-568
発行日: 1988年
公開日: 2010/03/12
ジャーナル フリーThe applicability of clinical laboratory robot LAS-2000A for screening kits to detect anti-HIV and anti-ATLA antibodies in the sera from hospitalized patients using the gelatine particle agglutination method was compared with manual operation. There was very little reagent loss during the experiment with either procedures. Processing was much faster with the LAS-2000A, but the titer of the positive sera was about 1 log2 unit higher than that with the manual operation. This difference appeared to be due to inadequate serum dilution process with the LAS-2000A. Although LAS-2000A requires improvement in the dilution process, it is very useful with respect to economy of labor and protection of laboratory staff against infection diseases.抄録全体を表示PDF形式でダウンロード (472K) -
横山 繁樹, 細井 武光1988 年 34 巻 5 号 p. 569-573
発行日: 1988年
公開日: 2010/03/12
ジャーナル フリーPlasmapheresis using the automated membrane device (NDP-100) for plasma collection was carried out on 219 normal donors. The aim of this study was the evaluation of donor safety, the recovery rates of proteins and coagulation factors, and the efficiency of the plasma collection in Red Cross Blood Centers.
As to donor safety, there were no significant changes in the donor's physical and biochemical test results. Complement activation, as already indicated, was noticed to be slightly elevated. The obtained plasma showed good protein recovery such as total protein, albumin, IgG, fibrinogen and factor VIII and IX levels. However, this procedure required around 60 minutes to collect 400ml of plasma (needle to needle time), plus 15 minutes for set-up and priming the device. As a result, an operator can only carry out four plasmaphereses a day. Furthermore, because of the long needle to needle time, many donors who experienced the centrifuge system using Haemonetics PCS did not agree to the use of NDP 100 device for the following donation.
In conclusion, this system is required to shorten the time of the procedure.抄録全体を表示PDF形式でダウンロード (524K) -
中嶋 八良, 関口 定美, 伊藤 忠一, 徳永 栄一, 大久保 康人, 佐藤 暢, 清川 博之, 田村 真1988 年 34 巻 5 号 p. 574-575
発行日: 1988年
公開日: 2010/03/12
ジャーナル フリーPDF形式でダウンロード (174K) -
British Council輸血医学コース参加報告大戸 斉1988 年 34 巻 5 号 p. 576-578
発行日: 1988年
公開日: 2010/03/12
ジャーナル フリーPDF形式でダウンロード (338K) -
1988 年 34 巻 5 号 p. e1
発行日: 1988年
公開日: 2010/03/12
ジャーナル フリーPDF形式でダウンロード (78K)
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