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Volume 60 (2007)
- Issue 5 Pages 233-
- Issue 4 Pages 189-
- Issue 3 Pages 129-
- Issue 2 Pages 97-
- Issue 1 Pages 3-
Predecessor
Volume 60, Issue 5
Displaying 1-4 of 4 articles from this issue
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Original Papers
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Effects of Non-digestible Oligosaccharides with Different Properties on Ca and Mg Metabolism in RatsTsuneyuki Oku, Kenichi Tanabe, Yuki Watanabe, Haruko Ono, Mari Naruse, ...2007 Volume 60 Issue 5 Pages 233-240
Published: October 10, 2007
Released on J-STAGE: January 30, 2009
JOURNAL FREE ACCESSIn order to evaluate the effect of non-digestible oligosaccharides with different properties on calcium and magnesium metabolism, six Wistar male rats (3 wk) in each group were raised on 10% of fructooligosaccharide (FOS), lactulose (LAT), galactosylsucrose (GS) or isomaltooligosaccharide (IMO) containing diets instead of sucrose for 6 week, and the balance study of Ca and Mg was carried out for 3 days at 6th week after the start of experiment. Mild restricted feeding of diet was carried out to be equal quantity of diet for all groups every day. Intestinal absorption, urinary excretion, retention, and femoral bone content of Ca and Mg, and urinary deoxypyridinoline excretion were measured. Intestinal absorption and femoral bone contents of Ca and Mg were significantly higher in FOS and LAT groups than in the control group, and that of GS group was lower than that of FOS and LAT groups. IMO group was similar to the control group. These results suggest that the intestinal absorption of Ca and Mg depends on the quantity of oligosaccharide which reaches the large intestine, that is to be concerned with the digestibility of oligosaccharide. Therefore, the effect on Ca and Mg absorption from gastrointestinal tract was the greatest in non-digestible FOS and LAT groups, greater in partly digestible GS group and the lowest in digestible IMO group among 4 groups.View full abstractDownload PDF (883K) -
Yoko Nakashima2007 Volume 60 Issue 5 Pages 241-247
Published: October 10, 2007
Released on J-STAGE: January 30, 2009
JOURNAL FREE ACCESSTo investigate the influence of fat-feeding dams on the food choice of their pups after weaning, each three groups of dams were fed a low-fat diet (LFD), a control diet (CTD) or a high-fat diet (HFD) with added lard during pregnancy and lactation. Immediately after weaning, all pups were placed on a two-choice diet program of the LFD and the HFD for 5 weeks. No significant differences in body weight and energy intake were observed between these three groups of dams and their pups. Within first week after weaning, all pups ate a large amount of the HFD and the ratio of HFD intake (HFD intake/total intake) in three groups of pups were 85-90%. Although after week two after weaning, the HFD intake in pups nursed by dams fed the LFD and the HFD was about 85% (fat energy ratio, F ratio: 38%) and 90-95% (F ratio: 39-40%), respectively, that in pups nursed by dams fed the CTD decreased 60-65% (F ratio: 31%). Plasma triglyceride concentration in dams fed CTD and their 5 week-old pups was lower than that in the other two groups. These data lead us to conclude that if dams ate diet containing inadequate amount of fat, their pups would be deprived of their ability to eat adequately after weaning.View full abstractDownload PDF (413K) -
Tatsuhiro Usui, Mari Okazaki, Shinya Kamiuchi, Fumiko Suzuki, Hiroshi ...2007 Volume 60 Issue 5 Pages 249-255
Published: October 10, 2007
Released on J-STAGE: January 30, 2009
JOURNAL FREE ACCESSThe water-soluble extract (WER) was prepared from the culture medium of Ganoderma lucidum (Rei-shi), which was composed of bagasse and rice bran. WER had suppressive effects on postprandial blood glucose elevation using sugar tolerance tests in mice. Oral administration of WER (1 g/kg), which did not affect fasting blood glucose, showed significant suppression on the increase of blood glucose levels after loading of maltose (21% decrease in AUC) or starch (15% decrease in AUC), compared to the control mice. In vitro study showed that WER inhibited maltase, sucrase and α-amylase in concentration-dependent manner. These results suggest that WER has a glucose-lowering effect after loading sugar, which may be based on inhibition of the activity of saccharide hydrolyzing enzymes. Moreover, in the present study, we aimed to examine the effects of WER on voglibose. WER did not enhance the inhibitory effects of α-glucosidase on voglibose (1 μg/mL), nor on voglibose (0.035 μg/mL). In addition, oral administration of voglibose (0.1 mg/kg) with WER (1 g/kg) resulted in no significant change in AUC. These results indicate that concomitant intake of voglibose with WER may not cause additive effects on postprandial blood glucose elevation by food-drug interaction.View full abstractDownload PDF (676K)
Research Note
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Narumi Nagai, Naoko Kameda, Riyo Kobashi, Minako Nishida, Chika Horika ...2007 Volume 60 Issue 5 Pages 257-264
Published: October 10, 2007
Released on J-STAGE: January 30, 2009
JOURNAL FREE ACCESSThe present study was designed to verify the effect of L-carnitine intake on postprandial hunger feeling in young healthy females. With double-blind, crossover design (1 wk washout), 12 females (21.3±0.3 y) consumed a placebo or L-carnitine containing (300 mg per meal) formula diet as breakfast after overnight fasting. Satiety scores (visual analog scales; VASs), salivary cortisol, serum carnitine concentrations, blood glucose, and autonomic nervous system activity by means of heart rate variability power spectral analysis were measured before and after feeding for 6 h at intervals. Our data suggest that hunger feeling tended to be reduced by L-carnitine intake, involving the level of serum total-carnitine concentrations. Moreover, lower level of salivary cortisol concentrations was shown after L-carnitine containing meal (at 30 min and 2 h), however, the link between the salivary cortisol level and the reduction of hunger feeling was not fully understand.View full abstractDownload PDF (1798K)
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