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Volume 62 (2009)
- Issue 6 Pages 281-
- Issue 5 Pages 235-
- Issue 4 Pages 155-
- Issue 3 Pages 99-
- Issue 2 Pages 61-
- Issue 1 Pages 3-
Predecessor
Volume 62, Issue 6
Displaying 1-4 of 4 articles from this issue
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Review
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(2009 JSNFS Young Investigator Award)Kazuki Mochizuki2009 Volume 62 Issue 6 Pages 281-290
Published: 2009
Released on J-STAGE: January 29, 2010
JOURNAL FREE ACCESSJejunal expression of the genes for the vitamin A-binding protein CRBPII and the fatty acid-binding protein L-FABP is induced during the middle of the suckling period, whereas that of the genes for disaccharidase sucrase-isomaltase and the fructose transporter GLUT5 are induced from the middle to late suckling period. In this study, we demonstrated that induction of the CRBPII and L-FABP genes is mediated by one of the nuclear receptors, PPARα, whereas induction of the GLUT5 gene is regulated by the nuclear receptors for thyroid hormone (TRα-1) and glucocorticoid hormone (GR). Furthermore, we found that the signals of nutrients/hormones induce histone acetylation and binding of one of the chromatin remodeling factors, CBP/p300, to the upstream/transcriptional regions of these genes. Our results suggest that nutrients/hormones regulate the expression of jejunal genes, not only as activators of nucler transcriptional factors, but also as key factors for changing the remodeling of chromatin.View full abstractDownload PDF (1780K)
Original Paper
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Nao Kitamura, Ikuo Ohara2009 Volume 62 Issue 6 Pages 291-296
Published: 2009
Released on J-STAGE: January 29, 2010
JOURNAL FREE ACCESSThe present study was designed to examine changes of taste sensitivity in university female students during the menstrual cycle. Basal body temperatures were recorded every day for 3 months. Taste sensitivities were examined on seven different regions of the tongue for 4 basic tastes. Eleven out of 25 subjects showed normal basal body temperature patterns during the menstrual cycle. The tip of the tongue was the most sensitive site for discriminating taste. Taste sensitivities changed during the menstrual cycle. Sweetness was keen during the luteal and follicular phases and insensitive during ovulation and menstruation. Sourness was keener during the luteal phase than during ovulation. Sensitivities to the basic 4 tastes showed no relationship to each other between the follicular and luteal phases.View full abstractDownload PDF (887K)
Research Notes
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Association between Skipping Breakfast and Morning Gastric Motility Monitored by ElectrogastrographyShiori Wakisaka, Riyo Kobashi, Miyuki Hishikawa, Yukina Yamamoto, Masa ...2009 Volume 62 Issue 6 Pages 297-304
Published: 2009
Released on J-STAGE: January 29, 2010
JOURNAL FREE ACCESSElectrogastrography (EGG) is a noninvasive technique for measurement of gastric motility by recording gastric myoelectrical activity through cutaneous electrodes placed on the abdomen. We performed a one-week skipping breakfast test and a consecutive one-week refeeding test to examine the relationship between consecutive skipping of breakfast and morning gastric motility in 11 women (age 21.5±0.2 yr) who habitually ate breakfast almost every day. On the test days, we measured the subjects’ body composition, self-reported hunger and appetite scores (by using visual analog scales), EGG (to determine the Normal power, % Normal power, and dominant frequency [DF] of gastric myoelectrical activity with the band set at around 3 cycles per min), and electrocardiogram (to determine cardiac autonomic nervous system activity) at about 9 a.m. after an overnight fast. A one-week period of skipping breakfast diminished % Normal power and the DF, but not to a significant degree. After the refeeding period, a further decrease in the DF was observed (p=0.077 versus baseline). Moreover, hunger (r=0.55, p=0.077) and appetite scores (r=0.60, p=0.051) were weakly but positively correlated with % Normal power. Our results suggest that a one-week period of skipping breakfast tends to decrease gastric motility in young women who normally have a habit of eating breakfast, and that the intensity of morning gastric motility may be involved in hunger sensation or appetite.View full abstractDownload PDF (885K) -
Takeshi Ohkubo, Toshihiro Ito, Hidehiko Hibino2009 Volume 62 Issue 6 Pages 305-309
Published: 2009
Released on J-STAGE: January 29, 2010
JOURNAL FREE ACCESSPolicosanol is a long-chain aliphatic alcohol composed of 20 or more carbons, and is known to reduce serum lipids and improve liver function. We confirmed that administration of policosanol at 40 mg/day for 6 weeks led to significant reductions in acetaldehyde concentrations in eight healthy adult men. Blood acetaldehyde concentrations at 180 min after consumption of 25 g of ethanol were also decreased. Before policosanol supplementation, the mean acetaldehyde level (5 μmol/L) was 13.0 μmol/L, but none of the subjects had detectable acetaldehyde levels after the experiment. We performed this test in human subjects in order investigate the use of policosanol for prevention of hangover after alcohol consumption.View full abstractDownload PDF (727K)
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