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Volume 52 (1999)
- Issue 6 Pages 343-
- Issue 5 Pages 263-
- Issue 4 Pages 183-
- Issue 3 Pages 129-
- Issue 2 Pages 71-
- Issue 1 Pages 3-
Predecessor
Volume 52, Issue 3
Displaying 1-7 of 7 articles from this issue
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Kazuhiro Uchida, Hiroyuki Imamura, Noriko Miyamoto, Tomoko Shirota1999 Volume 52 Issue 3 Pages 129-134
Published: June 10, 1999
Released on J-STAGE: December 10, 2009
JOURNAL FREE ACCESSA study was conducted to examine the effects of exercise intensity on the duration and magnitude of excess post-exercise oxygen consumption (EPOC) in seven young women who were in the same phase of the menstrual cycle. The subjects exercised on separate days for 30min at an intensity of 40%, 50% or 70% of maximal oxygen uptake (VO2 max) on a cycle ergometer. Oxygen uptake, respiratory exchange ratio, and heart rate were measured while the subjects rested in a sitting position for 4h after exercise. The results were compared with those of an identical control experiment without exercise. EPOC lasted for 17.7±11.1min (40% VO2 max), 23.7±8.1min (50%), and 41.3±22.6min (70%), and the corresponding EPOC and excess energy expenditure were 1, 336±838ml and 6±4kcal, 2, 011±646ml and 10±3kcal, 3, 564±1, 627ml and 17±8kcal, respectively. These mean differences were statistically significant (p<0.05). The present results indicate that exercise intensity affects both the duration and magnitude of EPOC.View full abstractDownload PDF (891K) -
Goro Hori, Kazuhiro Yamamoto, Koji Morishita, Saori Mukawa, Toshikazu ...1999 Volume 52 Issue 3 Pages 135-145
Published: June 10, 1999
Released on J-STAGE: December 10, 2009
JOURNAL FREE ACCESSA soybean protein pepsin-hydrolyzate with bound phospholipids (SPHP-p) was prepared, and its effects (at 1-20% in the diet) on cholesterol levels were examined in rats. All the rats were fed a cholesterol-enriched diet for 10 days, followed by the experimental diets for a further 9 days. SPHP-p dose-dependently reduced the levels of serum and liver cholesterol which had already accumulated within the body. The cholesterol-reducing effect of SPHP-p was more marked in the cholesterol-enriched (0.5%) diet group than in the cholesterol-free diet group. Another preparation from soybean protein hydrolyzed with microbial protease instead of pepsin (SPHP-s) was also examined, and was shown to suppress cholesterol absorption by Caco-2 cells in vitro, and to reduce the levels of serum and liver cholesterol in rats fed a cholesterol-enriched diet with a potency comparable to that of SPHP-p. These results indicate that both SPHP-p and SPHP-s can not only suppress the accumulation of exogenous cholesterol, but also reduce cholesterol which has already accumulated within the body by suppressing the absorption of cholesterol in the intestinal tract.View full abstractDownload PDF (3072K) -
Mayumi Kotani, Akihito Fujita, Toshio Tanaka1999 Volume 52 Issue 3 Pages 147-151
Published: June 10, 1999
Released on J-STAGE: December 10, 2009
JOURNAL FREE ACCESSThe inhibitory effects of persimmon leaf extract on Type I and Type IV allergic responses were examined. Persimmon leaf extract inhibited the release of histamine from human basophilic leukemia cells (KU812) stimulated with anti-Fc ε receptor monoclonal antibody (CRA-1), the 24-h homologous passive cutaneous anaphylaxis (PCA) reaction in mice, and contact dermatitis induced by 2, 4-dinitrofluorobenzene (DNFB) in mice. These results indicate that persimmon leaf extract possesses an anti-allergic action.View full abstractDownload PDF (715K) -
Keiko Yoshida, Shigeko Tsurushiin, Hiroyasu Fukuba, Rimiko Shimamura, ...1999 Volume 52 Issue 3 Pages 153-156
Published: June 10, 1999
Released on J-STAGE: December 10, 2009
JOURNAL FREE ACCESSACE inhibitory substances in black matpe constituted a hydrophilic group with a molecular weight of about 400-800, estimated by gel filtration on a Sephadex G-15 column. These inhibitory substances could not be separated using reverse-phase HPLC, gel filtration or ion exchange columns. The ACE inhibitory substances contained phytic acid, which when extracted had 40% of the total activity. When the ACE inhibitory substances were analyzed by TLC, some ninhydrin-positive spots were observed, whereas the phytic acid fraction contained no ninhydrin-positive spots. These results suggest that the substances are a mixture of phytic acid and ninhydrin-positive material.View full abstractDownload PDF (572K) -
Masanori Yamanaka, Muneo Saito1999 Volume 52 Issue 3 Pages 157-162
Published: June 10, 1999
Released on J-STAGE: December 10, 2009
JOURNAL FREE ACCESSThe influence of protein, methionine, a crystalline amino acid mixture, oil or cellulose in the diet and the method used for diet sterilization on the fresh weight or total nitrogen (N) content of the cecum was examined in germ-free (GF) and conventional (CV) mice. These results showed that the fresh weight of the cecum in GF mice was much higher than that of CV mice fed the same diet, whereas the total N content of the cecum was less in GF mice than in CV mice. The cecum of mice given an amino acid mixture as the N source was lighter than that of mice given a purified whole-egg protein diet as the N source. The effect of the diets on shrinkage of the enlarged cecum in GF mice was insignificant compared with the action of several microbes in the gastrointestinal tract of CV mice.View full abstractDownload PDF (944K) -
Asako Takenaka1999 Volume 52 Issue 3 Pages 163-166
Published: June 10, 1999
Released on J-STAGE: December 10, 2009
JOURNAL FREE ACCESSInsulin-like growth factor-I (IGF-I) is an important growth factor for postnatal growth, and its plasma concentration is known to be regulated by nutrition. To investigate the mechanisms of regulation of IGF-I activity by IGF-I receptor (IGF-IR) and IGF-binding protein (IGFBP) under various nutritional conditions, the mRNA content and protein level of IGF-IR and IGFBP were studied with rats fed diets containing low amounts or a low nutritional quality of protein. The IGF-IR mRNA level and IGF binding activity in various tissues of the rats were not affected by dietary protein malnutrition. Among IGFBP-1-4, which are thought to be the main IGFBPs in plasma, the plasma IGFBP-1 concentration showed the greatest increase in response to dietary protein deprivation. The increased plasma IGFBP-1 level was accompanied by an increase in both liver mRNA content and the rate of transcription of its gene. Transient transfection analysis of deletion mutants demonstrated that the sequence -112--81 by 5′ to the transcription start site was responsible for the induction of IGFBP-1 gene transcription by dietary protein deprivation.View full abstractDownload PDF (618K) -
Kazuya Yamada, Tamio Noguchi1999 Volume 52 Issue 3 Pages 167-173
Published: June 10, 1999
Released on J-STAGE: December 10, 2009
JOURNAL FREE ACCESSDietary carbohydrates regulate the expression of genes involved in carbohydrate and lipid metabolism. Although this regulation may be mediated by insulin, there is a considerable amount of evidence indicating that carbohydrates or their metabolites, and not insulin itself, are directly involved in gene regulation. The L-type isozyme (LPK) gene of pyruvate kinase, an important glycolytic enzyme, is a good example. This gene is expressed in liver, kidney, small intestine, and pancreatic β-cells, and is stimulated by carbohydrates such as glucose and fructose at both the transcriptional and post-transcriptional levels. Two cis-acting regulatory elements named L-II and L-III are required for transcriptional stimulation of the LPK gene by carbohydrates. Although the L-III element is itself responsive to carbohydrates, L-II functions as an accessory element. Both nuclear factor 1 proteins and hepatocyte nuclear factor 4 bind to the L-II element. Further studies have suggested that the former is involved in carbohydrate stimulation of the LPK gene. However, the L-III element binding protein that is involved in carbohydrate regulation remains to be clarified. Available evidence suggests that the carbohydrate signaling pathway to the LPK gene includes a glucose metabolite, possibly glucose 6-phosphate or xylulose 5-phosphate, as well as phosphorylation and dephosphorylation mechanisms.View full abstractDownload PDF (1217K)
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