Clinical effect and action of spa therapy on bronchial asthma were discussed in relation to the action mechanisms. 1. General spa therapy including swimming training in a hot spring pool, fango therapy and inhalation therapy with iodine salt solution was effective in patients with bronchial asthma. 2. The improvement of ventilatory function, especially in small airways was observed as direct action of spa therapy, accompanied with decrease in resistance of the airways and bronchial hypersensitivity. The function of adrenocortical glands and cardiovascular system was also improved or enhanced by indirect action of spa therapy. 3. Spa therapy was more effective and more valuable in cases with steroid-dependent intractable asthma, cases with Ib. bronchoconstriction+hypersecretion type and II. bronchiolar obstrction type and cases over 41 years of age. 4. Clinical effects of spa therapy on bronchial asthma was also found for longer than one year as distant effect, which was more predominant in cases with maintenance therapy.
It has been reported that thermoneutral (34.5°C) water immersion (WI) up to the neck causes remarkable natriuresis and suppression of plasma renin activity (PRA), however the mechanism is not fully understood. This present study consists of three experiments comparing the effect of WI in seated posture for 60-90min. with that of sitting posture in the air (Exp. 1); with that of WI in supine posture (Exp. 2); and with that of cold (25.0°C) immersion for 10min. (Exp. 3). Subjects were all healthy young men aged 20-25. The room temperature was 27-29°C. On Fig. 1 it can be seen that the suppression of PRA by WI was significant as compared with the preimmersion condition, while no significant change was observed in the control study. The suppression of PRA in Exp. 2 was observed to be almost equal whether in the supine posture or seated. On Fig. 3 the levels of PRA rapidly decreased with cold water immersion. The percent decrease of PRA both immersions were correlated (r=0.69, p<0.05) for this figure. From these data, it is postulated that suppression of PRA by thermoneutral water immersion was modified by the posture during immersion. This suggests we should take into consideration neurotic factors in PRA suppression other than just hydrostatic pressure and resulting increase in central blood volume.
We investigated the effects of artificial mineral bathing in water containing sodium sulfate and sodium bicarbonate on venous blood gas, blood pressure, heart rate, and deep body temperature in 10 patients with hypertension or history of hypertension. After a 10-minute bathing at 40°C, the parameters described above were carefully checked. The pH and PO2 levels in venous blood increased and the PCO2 level decreased after the artificial mineral bathing in comparison with plain water bathing. However, these changes were not statistically significant. The systolic blood pressure tended to decrease up to 10 hours after the artificial mineral bathing. The heart rate markedly reduced after the artificial mineral bathing and remained at a low level for 10 hours. The deep body temperature began to decrease 40 minutes after the artificial mineral bathing. However, it increased over the base-line level 6 hours later. From the above result, it is considered that artificial mineral bathing is useful for patients with hypertension.
A survey through general questionnaires was performed on those who visited the Hijiori, Yutagawa and Akakura hot springs in Yamagata Prefecture for thermalisme. A total of 548 replies were obtained and they were analyzed in comparison with the survey results reported by Sugiyama et al. about 30 years ago. Most of visitors were regular customers living in Yamagata Prefecture. Further, most of them, both men and women, were of age 60 or over. This fact was remarkably different from the investigation results of 30 years ago. The degree of satisfaction among visitors as to the effectiveness of thermalisme was high among most of those who visited there to relieve pain but not so high among those who visited there for their health or for resting.
The effect of Artificial CO2-bathing was compared with that of placebo bathing on patients with rheumatoid arthritis (RA). A large tablet containing sodium bicarbonate and citric acid, which is called Bub, was used to make CO2 gas as it dissolves in water bath. A placebo tablet, which is quite same in the appearance, has the substrate only and makes no gas. So the trial was performed by single blind method. Forty two RA patients (definite or classical) were tested by single bathing and other 40 RA patients, by serial bathing of 30 days (once a day). After a single bathing grip strength of the patients increased significantly in both groups, but more significantly in Bub group (p<0.01 vs p<0.05). The joint tenderness also reduced significantly after a single bathing in both groups, almost equally. However plasma β endorphin levels were little changed after single bathing in both groups. By serial bathing of 30 days, Lansbury's activity index, ADL score, and pain score were all changed insignificantly in each group. However Bub group showed a tendency to improve in the 3 parameters, whereas placebo group did a tendency to deteriorate. From the above results it was considered that artificial CO2-bathing may exert more beneficial effects on RA patients, as compared with plain water bathing.
The effectiveness and safety of Stereodynator 828 treatment was tested on 32 patients who were mainly complaining of pain such as lumbago. As a result of overall evaluation, the treatment was found to be extremely effective in one case, effective in 20 cases, and fairly effective in 11 cases. In no cases did the treatment prove to be non-effective or harmful. Biochemical blood and urine tests, blood pressure and heart rate measurements were conducted on all patients before and after the clinical study. No abnormal changes in the above factors or side effects were found in any patient. From the above, we conclude that Stereodynator 828 is quite effective in relieving pain and also is very safe in treating patients.