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Toshikazu NAGATO, Masami NAGAKI, Goichi MATSUMOTO, Keizo MORI, Hiroyuk ...
1988 Volume 37 Issue 3 Pages
527-539
Published: July 10, 1988
Released on J-STAGE: September 07, 2011
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The postnatal differentiation of the submandibular gland of 0 day to 3 month old rats was studied under the light and electron microscope.
Lipid droplets accumulated in the basal cytoplasm of secretory cells of the terminal tubule at 1 day and 2 days of birth. No lipid droplets were, however, found in the gland at birth. Lipid droplets began to decrease in number from 3 days after birth, and few lipid droplets were seen in the gland of 5 day old rats. Histochemical staining with Sudan III and Nile blue suggested that the lipid droplets are mainly triglyceride.
From the specimens which were serially sectioned and stained with Alcian blue, it was defined that the rat submandibular glands contain mucous cells or mucous acini. At birth, a single mucous cell was found occasionally in some terminal tubules and was observed to become a cluster in later stages. There were several mucous acini in a gland of 4 week and of 3 month old rats, and there were 5 to 20 well developed mucous acini in that of 6 month old rats.
The relative area occupied by a terminal tubule cell per terminal tubule was measured on sections. In rats weaned at 3 weeks after birth, the percentage on 3, 4, 5 and 6 week olds were 45.5%, 15.8%, 4.3% and 1.0% respectively. On the other hand, in rats weaned at 4 weeks after birth, the percentage on 4, 5 and 6 week olds were 41.8%, 13.7%, and 3.4% respectively.
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Michitaka MURAKAMI, Toshikazu NAGATO, Hiroaki TANIOKA
1988 Volume 37 Issue 3 Pages
540-547
Published: July 10, 1988
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To elucidate the morphological differentiation of myoepithelial cells, the rat sublingual glands from day 18 in utero to day 60 after birth were examined under the fluorescent microscopy using NBD- phallacidin.
In 18 days fetuses the sublingual gland showed clear fluorescence at the luminal surface of immature terminal portions and the boundary between adjacent glandular cells. At birth some terminal portions became associated with flat cells showing diffuse, weak fluorescence. These flat cells are thought to be immature myoepithelial cells. In 2 day old animals flat cells with a few short, broad cellular processes appeared. Thereafter, these cells rapidly increased in number and bundles of actin filaments were recognized in their cytoplasm, and flat cells showing diffuse, weak fluorescence disappeared from the terminal portion of the gland by day 10 after birth. In 10 day old specimens some of myoepithelial cells were identified as stellate cells with several ramifying cellular processes which contained a few thin distinct bundle of actin filaments. On day 20 after birth almost all myoepithelial cells had several cytoplasmic processes, each containing a few distinct bundles of actin filaments. In 30 day old animals myoepithelial cells frequently consisted of the cell body with abundant intricate bundles of actin filaments and cytoplasmic processes filled with numerous bundles of actin filaments. Thereafter the accumulation of actin filaments became more obvious, and the myoepithelial cells on day 60 after birth exhibited intense fluorescence so that individual bundles of actin filaments were no longer distinguishable.
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Atsuo HIROZANE, Yoshihisa FUJIKURA, Tomoo SAWADA, Hiromichi KUNIKI, Te ...
1988 Volume 37 Issue 3 Pages
548-553
Published: July 10, 1988
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Major histocompatibility complex (MHC) Class 1 molecules are present in most tissues. We examined the appearance of Class 1 antigen in the rat salivary tissues of each age (newborn, 10 days, 12 days, 14 days and adult) by immunofluorecence staining and immunohistochemistry. Monoclonal antibodies (HAM 2 or OX 18) are specific antibodies to rat MHC Class 1 antigen (Fukumoto, et al., 1984, 1982). We used FITC or HRP conjugated anti-mouse immunoglobulin to detect HAM 2 or OX 18 antibody.
These findings provide the following evidences.
1) MHC Class 1 antigen in the submandibular gland accumulated in the secretory duct cell.
2) MHC Class 1 antigen was recognized on the cell surface by immunoelectron microscopy.
3) In the parotid gland, less accumulation of class 1 antigen was observed. In the sublingual gland, accumulation of class 1 antigen was not recognized.
4) Class 1 antigen was first observed on day 10 after birth in the submandibular gland.
5) It is suspected that appearance of Class 1 antigen in the submandibular gland may be related to the uptake of the diet.
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III Report of the peripheral blood examinations and Fe/Zn deficiencies
Tetsuo NAGAI, Tsutomu EBIHARA, Hiroaki SHINTANI, Tsutomu OCHIAI, Hitos ...
1988 Volume 37 Issue 3 Pages
554-561
Published: July 10, 1988
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Analyses of peripheral blood examinations, for serum iron and serum zinc were performed in 90 cases of glossodynia.
The hematocrit value, hemoglobin mean corpuscular volume, and concentration of serum iron and zinc were lower than in the healthy controls, but did not show any significant differences to the group with stomatitis.
The results suggest that anemia and iron and zinc deficiencies in the patients with glossodynia were not specific changes, but were results due to the changes of oral mucosal diseases.
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Toshihiro HIRAI, Osamu TANAKA, Yasuhiro IKEDA, Toshihiko YAJIMA, Kinai ...
1988 Volume 37 Issue 3 Pages
562-570
Published: July 10, 1988
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Seventy-eight elderly persons (mean age: 77.3 yr) in a geriatric hospital were surveyed to study the relation between masticatory functioning and mental and physical activities in elderly persons.
The masicatory function was represented as a “Denture Score” by evaluating denture retention, stability, and occlusion, and denture satisfaction inquires were made. A high correlation was observed between denture score and satisfaction (r=0.82). The Hasegawa dementia test score, ADL score, and grip strength of each patient were investigated.
The “Denture Score” and dementia test score, ADL score, and grip strength were found to correlate statistically (p<0.01, p<0.05 and p<0.01).
Dementia test score, ADL score, and grip strength were compared statistically for persons using dentures (dentures group) and persons not using dentures (the non-denture group). The score for the non-denture group was found to be significantly lower than that for the dentures group (p<0.01).
The masticatory function seemed to closely affect mental and physical activity in the elderly persons.
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Fumihiro OHSAKA, Souichiro ASANAMI, Shinobu IKEUCHI, Yutaka OKADA, Mak ...
1988 Volume 37 Issue 3 Pages
571-580
Published: July 10, 1988
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Microscale two-dimensional gel electrophoresis method for simultaneous analysis of ten samples by the use of submerged SDS polyacrylamide gel electrophoresis in second dimension is described.
The resolution and reproducibility are comparable to that obtained with other systems, but this system is relatively simple and easily constructed and used.
The use of this method increased the capability of two-dimensional micro gel electrophoresis for analysis of multisamples.
The hamster tongue mucosa proteins were analysed using this two-dimensional gel electrophoresis method. The polypeptide pattern of tongue mucosa was quite similar to that of the skin but was different from those of the submandibular gland, liver and serum. There was a common polypeptide spot (isoelectric point 5.8, molecular weight 47, 000) in tongue mucosa and skin, and this was not detectable in other organs.
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with special reference to the application experience of the Advance laser flowmeter ALF-2100
Haruhiko SAKAMOTO, Yutaka IMAI, Tatsuo KASAKURA, Yukihiro YOKOKURA, Ma ...
1988 Volume 37 Issue 3 Pages
581-585
Published: July 10, 1988
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The extent of increase in the peripheral circulation of the hamster's buccal pouch by the actions of varying magnetic field of 2 kinds of permanent magnets of different gauss was determined by the advance laser flowmeter·ALF 2100, and the following conclusions were obtained:
1) Control (blood flow in the buccal pouch):
Blood flow of 3.8±0.4ml/min/100 g was observed.
2) Blood flow in the buccal pouch as applied with a magnet of 1200 gauss (9 mmdiameter, 7 mm-height, cylindrical):
Blood flow of 10.2±1.3ml/min/100g was observed with a significant diffecence (p<0.01) from the control.
3) Blood flow in the buccal pouch as applied with a magnet of 1200 gauss (15 mmdiameter, 7 mm-height, cylindrical):
Blood flow of 17.1±1.7ml/min/100g was observed with a significant difference (p<0.001) from the control.
The above results confirmed that a magnet of larger diameter caused more blood flow than that of smaller diameter. It was also revealed that this action of the applied magnet was exerted immediately upon the blood flow and kept this constant regardless of the time, and returned to original values immediately after stopping.
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Hideaki SAKASHITA, Masaru MIYATA, Morimoto HAYASHI, Yuichi NAKAI, Eisu ...
1988 Volume 37 Issue 3 Pages
586-599
Published: July 10, 1988
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One hundred and twelve cases of salivary gland tumors, 53 from parotid glands, 16 from submandibular glands, 1 from sublingual gland, and 42 from minor salivary glands, were studied. They were composed of 79 cases of benign tumors and 33 cases of malignant tumors. Pleomorphic adenomas, which comprised 62.5% of all the tumors and 88.6% of the benign tumors, were most common. Generally, these tumors were found more frequently in females than in males.
Mucoepidermoid tumors were the most common tumor among the malignant tumors.
Parotid gland tumors were most common, which comprised 48.4% of all the cases.
The incidence of the submandibular gland tumors in this study is higher than those reported in the English literatures.
Pleomorphic adenomas were classified according to Shirakawa's classification with some modification by Sakasita. W e suggested that these tumors should be classified into four subclasses. W e found that the presence of adipose tissue in theses tumors was more common in minor salivary gland tumors than in the tumors of other sites. The capsules of these tumors were complete in almost all the cases, but eruptions and daughter tumors in the capsule were seen in 41.9 % of the cases. The surgical treatment of these gland tumors should be partial or total resection of the involved salivary gland because of the high recurrent rate after only enucleating the tumor mass.
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Harumi ARAKI, Kenji KAKUDO, Yoshinobu KUBO, Rikiya SHIRASU
1988 Volume 37 Issue 3 Pages
600-608
Published: July 10, 1988
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This paper describes a method and an apparatus of standardized radiography of the temporomandibular joint for the rhesus monkey.
The apparatus consists of an ear-rod which fits into the auditory meatus and a head positioner which connects an implantation on the frontal. The X-ray tube is at the TMJ which can be examined and at +20 degrees in Camper's plane, and at -5 degrees in midsagittal plane.
The results indicated that TMJ radiographs taken by the apparatus with three fixed points were duplicable.
It is suggested that TMJ radiograph susing this method provide valuable findings in diagnosis and treatment.
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Ryoichi KAWABE, Ken ITO, Takayo ISHII, Kiyohide FUJITA, Tohru INOUE, M ...
1988 Volume 37 Issue 3 Pages
609-617
Published: July 10, 1988
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Tissue and cellular kinetics in human oral tumors and oral mucosa (healthy and diseased) were examined
in vitro by means of bromodeoxyuridine (BrdU) and its monoclonal antibody.
Soon after surgical removal, the tissues were cut into cubes about 1 mm3 and incubated in the RPMI medium containing BrdU under hyperbalic oxygen, followed by fixtation in formalin, and then embedded in paraffin. Deparaffinated thin sections were treated with 4 N HC1 for denaturation of the DNA double strand. Anti-BrdU antibody was detected using an indirect immunohistochemical procedure.
This method provided us with detection of the DNA synthesis (S-phase) cells and also their morphology and distribution in tissues.
In addition, comparison of the
in vivo and
in vitro labeling index in the filiform papillae of the mouse tongue showed good correlation. This result revealed the utility of the BrdU
in vitro method for the kinetic study of oral mucosa and tumors.
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A study of methods and observation during phona-tion of vowels in cleft palate patients
Kimie MORI
1988 Volume 37 Issue 3 Pages
618-647
Published: July 10, 1988
Released on J-STAGE: September 07, 2011
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Velopharyngeal (VP) movement of 5 normal adult and 28 postoperative cleft palate (cp)(7 with sufficient VP function; S group, 10 with insufficient VP function; IS group, 11 with border VP function; B group) subjects were investigated using a new technique for simultaneous observation of multitransducer-ultrasonic and nasopharyngeal fiberscopic recordings after recognition of reliability and validity of the method.
The results were as follows:
1) Mean VP orifice size of normal adult subjects was 4.51±0.37 cm
2 in the resting position.
2) Mean orifice size of S group was smaller than that of normal subjects in the resting position.
3) Mean orifice of CP subjects size was S<B<IS group in the resting position and during phonation of /a/ and /i/.
4) Mean medial movement of the lateral pharyngeal wall (LPW) in CP subjects was smaller than in normal ones during phonation of /a/ and /i/.
5) Mean vertical movement of the LPW in CP subjects was almost the same as in normal subjects during phonation of /a/ and /i/.
6) Mean duration of the VP movement in CP subjects was almost the same as in normal subjects during phonation of /a/ and /i/.
7) The voice onset-time was immediately before VP closure in normal subjects and S group, but immediately after it in B group and IS group.
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Yutaka OKADA, Fumihiro OHSAKA, Souichiro ASANAMI
1988 Volume 37 Issue 3 Pages
648-653
Published: July 10, 1988
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An ultrasonic osteotome for cutting the jaw bone was made on an experimental basis. Then, its clinical usefulness was studied in various aspects, and the following results were obtained.
1. Local heat production by the ultrasonic saw could not be neglected; however, water cooling provides an adequate control of local heat generation.
2. Histopathological studies of the amputated bones revealed that tissue damage was minimal and that the wound healing was satisfactory.
3. Practically, the cutting of the bone is well-controlled with the probe tip touching the target gently; precise manipulation is also easy without giving much damage to the neighboring soft tissue. Therefore, the saw's clinical usefulness seems clear.
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Eiichiro ARIJI, Kenichi JINGU, Makoto MOTOOKA, Kouji MASUDA
1988 Volume 37 Issue 3 Pages
654-659
Published: July 10, 1988
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Twenty-one patients with squamous cell carcinoma of the oral floor treated at the Department of Radiology, Kyushu University Hospital from 1979 to 1986, were analyzed for the incidence of multiple primary cancers.
Eighteen patients were males and the overall mean age was 58 years old, but the ages from 42 to 76. According to the UICC (1978) classification, 11 cases were in stage I, 8 cases in stage II and 2 cases in stage III.
In all cases prospective radiological examinations of the gastro-intestinal tract were performed.
The incidence of multiple primary cancers in patients with cancer of the oral floor was 33%(7/21 cases), and that of synchronous cancers was 19%(4/21 cases).
In 3 of 4 patients with synchronous cancers, the secondary tumors were detected by radiological examinations of the gastro-intestinal tract before they complained of any symptoms.
These results show the high incidence of multiple primary cancers in patients with cancer of the oral floor and prove that radiological examinations of the gastro-intestinal tract are useful for detection of the secondary tumors.
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Hitoshi TANABE, Tomoki MIZOBE, Koumei SHIGEMURA, Michihiko SUZUKI, Yos ...
1988 Volume 37 Issue 3 Pages
660-665
Published: July 10, 1988
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Adenomatoid odontogenic tumor is known by many terms.
The earliest cases appear to have been reported by Dreibladt as pseudo-adenoma adamantinum and by L'Esperance as glandular adamantinoma.
Later reports referred to it as an epithelial tumor associated with developmental cysts, adenoameloblastoma and adenomatoid ameloblastoma.
In 1971, the term adenomatoid odontogenic tumor was adopted by W HO, and this has been commonly used since then.
This tumor is rare and it comprises 3 % of all odontogenic tumors of the jaw.
This article is based on the experience gained from one case study.
The patient is a 24 year old male, who was referred to our hospital by a dentist who found in an X-ray examination an osteolytic lesion within the left maxillary sinus impacted canine.
Treatment involved routine surgical removal, and there were no noteworthy complications.
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Kazuya KITAMURA, Yoshio HIRANO, Jouji NOMURA, Masanori OHNISHI, Mutsuo ...
1988 Volume 37 Issue 3 Pages
666-673
Published: July 10, 1988
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The occurance of Schwannoma is relatively rare in the regions of the jaw and the oral cavity. It originates mostly in the tongue. Recently we experienced two cases of solitary Schwannomas of the tongue.
Case 1: A 23 year-old woman visited our hospital with a chief complaint of uncomforta-bleness of a tumor near the left-side of the tongue tip. After excision of the tumor under local anesthesia, it was found to be encapsuled. Under light microscopy, it showed the picture of both Antoni type A and B. In addition the reactivity in the tumor cell was revealed to be positive by an immunohistochemical study using the antibody of S-100 protein.
Case 2: The patient was a 62 year-old woman. She had a tumor on the left-side of the tongue. After excision of the tumor similarly to Case 1, it was found to be encapsuled. Under light microscopy, it showed the picture of neither Antoni type A nor B and it was suggested to be a Neurofibroma. But from electron microscopic findings it was diagnosed as a Schwannoma and the reactivity in the tumor cell and the collagen fiber was revealed to be positive by an immunohistochemical study using the antibody of S-100 protein.
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Kazue YAMAGUCHI, Tsutomu OHKUBO, Kiyoshi OOYA, Carlos HERNANDEZ
1988 Volume 37 Issue 3 Pages
674-679
Published: July 10, 1988
Released on J-STAGE: September 07, 2011
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An eighteen year-old Japanese male with extranodal malignant lymphoma suffered from leukopenia and opportunistic infections (candidiasis in the digestive tract, herpes zoster in the lower extremity) during treatment with radiation and chemotherapy. He died of pneumonia and massive bleeding from a gastric ulcer by candidiasis after a three year course. The autopsy of this present case disclosed the fungal infection in the digestive tract and suggested that a biopsy from the oral cavity is useful for the definitive diagnosis of candidiasis.
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Teruhiko ISHII, Minoru HORI, Hiroyuki NAKAMURA, Mitsuhiro SATO, Takash ...
1988 Volume 37 Issue 3 Pages
680-688
Published: July 10, 1988
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This study examined the long-term effects of surgical repositioning of teeth in young patients. These patient's teeth exhibited abnormal direction of eruption and/or malpositioning. Some teeth were impacted with associated follicular cysts. All teeth were also classified according to the degree of root development: 1/4 of normal size (1/4), 1/2 of normal size (1/2), 3/4 of normal size (3/4), near complete or complete. Materials and methods: There were 16 patients with a total of 23 teeth which were surgically repositi oned. Patient's average age was 11.1 years, (range: 6 to 15). Pertinent information on each tooth's condition was gathered. Teeth were classified by the degree of root development, as outlined above. Each year for five years after surgery, radiographs were taken to assess (1) root devolopment, (2) pulp-space obliteration, (3) pulp necrosis, and (4) root resorption. Results:(1) Root development; of 23 teeth, 15 were incomplete prior to the operation (3 were 1/2, 12 were 3/4). The radiographs showed after 5 years, 6 of these 15 teeth had developed complete roots (2 were 1/2, 4 were 3/4), 7 had developed nearcomplete roots, and 2 showed no change. (2) Pulp-space obliteration; among the 15 incomplete teeth, the pulp space had been obliterated in 14. (3) Pulp necrosis; six teeth with no obliteration required further root canal treatment (3/4-1 tooth; near complete-2 teeth, complete-3 teeth). (4) Root resorption; no teeth exhibited internal ro ot resorption. Ten teeth exhibited external root resorption, in the following categories: surface resorption-8 teeth, inflammatory resorption-2 teeth, replacement resorption-0 teeth.
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Shinichi YAMAGAMI, Tateharu KAWASAKI, Nobuo TAMURA, Shoko MURAYAMA, Ts ...
1988 Volume 37 Issue 3 Pages
689-695
Published: July 10, 1988
Released on J-STAGE: September 07, 2011
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Two cases of TMJ ankylosis were treated successfully by surgery and subsequent exercise of the jaw by specially designed mouth gags and jaw traction followed by either orthodontic and prosthetic correction or prosthetic adjustment of occlusal disharmony.
The first case was a 25-year-old female who had jaw movement limitation due to TMJ ankylosis resulting from mandible fracture suffered at the age of 4. The condition persisted despite repeated operations in another hospital. The ankylosis was relieved by excision of scar tissue and extensive ostectomy of the mandibular ramus on the right side and condylectomy on the left side. Postoperative exercise of jaw opening was accomplished by screw-type mouth gags which enabled her to retain the mandible in the opened position. Development of the open bite resulting from the decreased height of the mandibular ramus was decreased by upward traction of the mandible by intermaxillary elastics and a chin cap with pivoting plates placed in the molar regions. The remaining occlusal disharmony was corrected by orthodontic alignment of crowding incisors and restoration of the molar relationship by bridge prostheses. In the second case, the fibrous ankylosis of the bilateral TMJ which developed due to inappropriate jaw exercise after mandibular fracture was also treated by conventional condylectomies and subsequent management as employed in the first case. It is stressed here that postoperative management by a combined approach is essential for optimal results.
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Takahide KOMORI, Osamu SATO, Yoshiyuki MORI, Masatoshi ISHII, Shoji EN ...
1988 Volume 37 Issue 3 Pages
696-701
Published: July 10, 1988
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In this report we presented a case of emphysema of the parotid gland induced by abnormal habit.
The patient was a 45-year-old man. In Sept. 1983, he noticed painless swelling of the left cheek. In Feb. 1985, concerned about the swelling which had continued to grow at times, he visited a clinic of an otorhinolaryngologist. However he received no cure because no swelling was found at that time. On Dec. 3, 1986, when he was admitted to a hospital for a physical examination, the swelling of the same region was pointed out by the doctor. And on Dec. 12, he was referred to our university clinic.
In the clinical examination, a diffuse swelling of the left cheek was observed. W hen we pressed the bilateral parotid gland regions, we felt as if we had pressed a mass of flour. And foamy saliva was ejected from the parotid papilla with air. CT scan and sialogram revealed air in the bilateral parotid glands and ducts.
Clinical diagnosis of emphysema of the bilateral parotid glands was made. This emphysema was considered to be induced by the abnormal habit that he had puffed out his cheeks strongly with his breath many times since he was 11 years old.
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Yuichi TANIE, Akihiko NAGAI, Tetsuji UEDA, Norichika TATEMATSU, Nobumi ...
1988 Volume 37 Issue 3 Pages
702-709
Published: July 10, 1988
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In the right molar region of the mandible in 1 patient, chronic suppurative osteomyelitis was found. In addition to surgical therapy, continuous perfusion therapy was attempted.
Fosfomycin-Na, mainly used in chemotherapy for systemic administration or local continuous perfusion therapy, appeared to be quite effective clinically.
In continuous perfusion, the use of a double serum tube raised the efficiency of controlling influx and efflux.
At present, two years postoperatively, the course is favorable and no signs of recurrence have been noted, but long term observations are necessary.
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Kenji KURASHINA, Akira OGISO, Toshikazu MINEMURA, Akira KOTANI, Shinji ...
1988 Volume 37 Issue 3 Pages
710-715
Published: July 10, 1988
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It is generally thought that the occurrence of a tongue abscess is very rare because of anatomic features of the tongue and recent development of antibiotics.
Three cases of tongue abscess are reported in this paper. Differential diagnosis for two of them was difficult due to the lack of fluctuation which is a typical feature of the abscess. Drainage and antibiotic therapy were effective, and there has not been any evidence of recurrence in all cases during the follow up period of about 1 year.
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Yoshiyasu YOSHIKAWA, Toshiaki HIRO, Masahiro NISHIMOTO, Atsuki TOGARI, ...
1988 Volume 37 Issue 3 Pages
716-722
Published: July 10, 1988
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Cephalometric analysis was examined on a case of the progressive facial hemiatrophy, and the following results were obtained.
1) Skeletal discrepancies in the lateral head plate, the maxillar and the mandible were retrusive to cranial base structures, and the PNS point was displaced to an upward position.
2) Abnormalities of the denture pattern of upper and lower incisors showed lingual inclination with deep overbite.
3) Skeletal discrepancies in the P-A head plate and the maxillar were remarkably atrophic and the left maxilla was more atrophic than the right one. The mandible showed lateral displacement to the left.
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Hirotoshi NAKAGAWA, Masaaki KOGA, Masaaki GOTO, Hisato KAMURA, Wataru ...
1988 Volume 37 Issue 3 Pages
723-732
Published: July 10, 1988
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A clinical study was made on 62 cases of postoperative maxillary cysts, which had undergone surgery between October 1981 and September 1986.
1. Six items, such as sexuality, affected sides, the age at onset, duration after the initial sinus surgery, the age at the initial sinus surgery, and chief complaint of the postoperative maxillary cyst bearing patients were examined.
2. Among 49 cases out of 62 patients, 110 teeth had undergone some dental treatment such as extraction, root canal filling, or apicoectomy.
3. Nineteen cases which had undergone a root canal filling or apicoectomy were followed up over 6 months, and in 15 of the cases new bone formation was observed at their apical region.
4. By adequate root canal treatment including apicoectomy, it was possible to conserve the teeth whose apexes were projected into the cyst or were adjacent to the cyst.
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Takashi OKUDA, Hiroyasu SAKAI, Takahiko NISHIWAKI, Iwao HYODO, Masaki ...
1988 Volume 37 Issue 3 Pages
733-746
Published: July 10, 1988
Released on J-STAGE: September 07, 2011
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Two cases of lymphoepithelial cyst that occurred in the neck were reported. First case A 73-year-old male complained of a tumor in the left cervical region for eighteen months. Ultrasonography revealed an echo-free cystic lesion with a well-defined margin. Sialography of the left submandibular gland showed a normal pattern, and
99mTcrenium scintigraphy showed that accumulation did not exist within the tumor but around it. A biopsy was attempted, yellowish brown-colored serous fluid was yielded. The wall was composed of stratified squamous epithelium and connective tissue, accompanied with lymphocytic infiltration. A relatively large cyst (6.5 × 4.0 × 3.0 cm) was obtained by surgical extirpation. The histopathology revealed a lymphoepithelial cyst with the germinal center in the wall. Second case: A 19-year-old female visited our department, because of the tumor in the right side of her neck for three months. Computed tomography revealed a cystic lesion with a thick wall. An exploratory puncture was attempted, and yellowish brown-colored serous fluid was aspirated. Microorganisms were not isolated from the fluid, and the cytology revealed squamous epithelium cells, lymphocytes, neutrophils, and histiocytes with no evidence of malignancy. Amylase activity of the fluid was slightly higher than that of serum (fluid: 810 IU/1, serum: 262 IU/1). Two epithelial cords were seen to extend from the surface of the cyst to the pharyngeal wall in the procedure of the surgery.
Careful differential diagnosis is necessary, because some cases of branchiogenic carcinomas are reported to arise from lymphoepithelial cysts. And further, in the cervical lymphnodes, metastatic carcinomas may undergo cystic degeneration resembling lymphoepithelial cysts.
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Report of a case and review of the literature
Gaku YAMAMOTO, Hiromi YAMAMOTO, Mitsunobu MORI, Kazusada YOSHITAKE, To ...
1988 Volume 37 Issue 3 Pages
747-755
Published: July 10, 1988
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In this report, a patient with a maxillary cementifying fibroma accompanied by a follicular alveodental cyst of the mandible is described.
The patient, a 41-year-old male, visited our hospital with tenderness of the right nasolabial groove and stuffiness of nose on July 4, 1985. On admission to our hospital, mild and diffuse swelling and tenderness were observed in the region of the right nasolabial groove. X-ray examination showed a clearbordered oval radioparent image of the size of a chicken egg containing uneven cloudy shadows in the right maxillary sinus. In CT, a clearbordered high density mass in the anterior maxillary sinus displaced the nasal septum. With a diagnosis of benign tumor of the maxilla and follicular alveodental cyst of the mandible, the lesions were resected transorally under general anesthesia on August 5, 1985. The patient has had an uneventful course for about 2 years and months to date, and no recurrence has been noted.
A review of 88 cases reported during the 48 years between 1940 and 1988 in Japan revealed that the tumor occurred most frequently in the 2th decade of life, more often affected females (65.1%), and involved the mandible in 77.6% of the patients, especially the molar region (40.1% of the patients).
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Atsushi YAZAKI, Kouiti WAJIMA, Masahiko SANTA, Masako IKAWA, Yutaka SU ...
1988 Volume 37 Issue 3 Pages
756-763
Published: July 10, 1988
Released on J-STAGE: September 07, 2011
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This article presents the necessity of final procedures in order to stabilize the recaptured disk with a mandibular anterior repositioning splint. A Mandibular anterior repositioning splint is widely used to treat patients with internal derangement of TMJ (anterior displacement of the disk with reduction), and many clinicians suggest the effectiveness of this therapy. Otherwise many studies showed recurrence of reciprocal clicking in the majority of patient when the splint was removed. It suggests that more permanent devices or a final procedure are needed to stabilize the mandible in the anterior position, and maintain the recaptured disk in a normal relationship to condyle. In adolescent cases with reciprocal clicking, we tried to stabilize the mandible, and to maintain the recaptured disk by passive eruption of molars without any prosthodontic treatment. We got a high efficacy with this final procedure.
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Kouiti WAJIMA, Masako IKAWA, Atsushi YAZAKI, Masahiko SANTA, Yutaka SU ...
1988 Volume 37 Issue 3 Pages
764-772
Published: July 10, 1988
Released on J-STAGE: September 07, 2011
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The purpose of this study was to clinicaly evaluate the efficacy of an antianxiety Etizolam (Depas
®) on temporomandibular joint disorders. The subjects were 33 patients (10 males and 23 females, average 34 years 5 months) with myogeneous complaints. Etizolam was administered in a daily dose of 1.5 mg (0.5 mg × 3 times), and all subjects didn't take any other treatment for 2 weeks.
1. The efficacy rate of all subjects was 76%.
2. As a result of analysing efficacy according to chief complaints, the efficacy rate was a high 100% for a group suffering from stiff neck and shoulder, 92% and for a group with opening pain at the TMJ.
3. As a result of analysing improvements of each sign and symptom, the efficacy rate was a high 92 % for headache, a high 88%, 81%, and 80% respectively, for tenderness of the temporal muscle, masseter muscle, and sternocleidomastoid muscle, and a high 84% for mouth opening pain.
Statistically significant differences (p<0.01) were found in the above signs and symptom between before and after treatment.
4. The efficacy rates of joint sound and trismus were a low 43% and 40%, because some cases of joint sound and trismus were caused by the internal derangement of the TMJ, and generally, internal derangement of the TMJ doesn't respond to drug treatment.
5. Side effects were observed in 3 cases, such as slight sleepiness.
6. It is suggested that Etizolam is a usefull drug for treatment of temporomandibular joint disorders, except in cases of chronic internal derangement of the TMJ
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Masaki ITO, Yujiro HANDA, Tadashi OKUTOMI, Norichika TATEMATSU, Nobumi ...
1988 Volume 37 Issue 3 Pages
773-778
Published: July 10, 1988
Released on J-STAGE: September 07, 2011
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The intermaxillary immobilization described by von Otten in 1981 is a method using a couple of special minihooks screwed in the spina nasalis and tuberculum mentale. This method is practicable for infant or edentulous patients since it does not rely on the teeth. In the clinical patient application, this method was revealed to be useful in treating condylar fractures of infants.
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Shigeru UENO, Kozo MUSHIMOTO, Mami HAENO, Rikiya SHIRASU
1988 Volume 37 Issue 3 Pages
779-783
Published: July 10, 1988
Released on J-STAGE: September 07, 2011
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This report describes a papillary cystadenoma of minor salivary gland origin that occurred in the buccal sulcus of a 67 year old male. The tumor was enucleated under local anesthesia. Histological examination revealed aggregated cystic cavities in the tumor. Remarkable papillary proliferation of the epithelial cells in these cavities was observed.
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Yutaka OKADA, Kazuko SAKAMOTO, Yasuhiro KASAZAKI, Souichiro ASANAMI
1988 Volume 37 Issue 3 Pages
784-790
Published: July 10, 1988
Released on J-STAGE: September 07, 2011
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Maffucci's syndrome is a dyschondroplasia manifested by multiple hemangiomas and is generally considered a relatively rare disorder.Recently we encontered a case of Maffucci's syndrome with apparent hemihypertrophy of the face, jaws, teeth and tongue.
A woman, 17 years old, presented with: generalized dark-red vascular naevus, distributed geographically and extensively; scoliosis; and asymmetry of the extremities, face, and head. Examination of the oral cavity revealed that the alveolar bones and tooth widths on the right were markedly larger than those on the left and that the maxillary center and raphe palati were deviated to the left with high palate, petechiae scattered on the palatal mucosa and lower gingiva on the lavial surface, and fibrous gingival hypertrophy. The tongue showed hypertrophy on the right half with the fungiform papillae hypertrophied like a strawberry. X-ray study revealed an accessory impacted tooth at the right premolar area.
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