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Volume 45, Issue 3
Displaying 1-15 of 15 articles from this issue
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Calcitonin Gene-Related Peptide (CGRP) Immunoreactive NerveBungo TAKANASHI, Hisao SHIGEMATSU, Keizo NAKA, Kiyoshi WATANABE, Seiji ...1996 Volume 45 Issue 3 Pages 221-226
Published: July 10, 1996
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSThe purpose of this study was to investigate the innervation of the inferior alveolar artery. The rats were divided into three groups: the superior cervical ganglion (SCG) was resected unilaterally in one group; the otic ganglion (OTG), unilaterally in one group; the SCG and OTG, unilaterally in the other. After a postoperative period of one week, the rats were sacrificed and examined by amine fluorescen histochemistry (acidic GA method), enzyme histochemistry of acetylcholinesterase (AChE) (TAGO's method), and indirect immunohistochemistry for calcitonin generelated peptide (CGRP).
Aminergic fluorescent nerve fibers and the AChE positive nerve fibers were observed in the adventitia of the inferior alveolar artery. Furthermore, CGRP-immunoreactive (IR) nerve fibers were established around the artery. Unilateral resection of the SCG resulted in complete loss of the ipsilateral amine fluorescence. After unilateral resection of the OTG, the AChE activity disappeared entirely on the ipsilateral side. The CGRP immunoreactivity on the nerve fiber around the artery was not changed after unilateral resection of the SCG and/or the OTG. Any CGRP-IR neurons were not seen in the SCG or the OTG. A very low number of CGRP-IR nerve fibers were observed in the SCG or the OTG.
These results suggested that the inferior alveolar artery is innervated by three different types of nerves. One of them is aminergic, originating from the SCG; another is cholinergic, arising from the OTG; and the third is non-aminergic/non-cholinergic, which is CGRP, originating from the gasserian ganglion.View full abstractDownload PDF (6852K) -
A Comparative Study between Two-Stage Palatoplasty Combined with Hotz's Plate Cases and Non-Cleft ControlsShingen FUKUHARA, Yasushi OHASHI1996 Volume 45 Issue 3 Pages 227-239
Published: July 10, 1996
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSThe growth of maxilla and the form of upper dental arch in patients with unilateral cleft lip, alveolus, and palate from newborn to 7 years of age following two-stage palatoplasty using Hotz's plate were studied. The subjects consisted of 36 unilateral cleft lip, alveolus, and palate patients (UCLP group). Serial maxillary casts were used for the analysis and compared with the non-cleft control group. The findings were as follows:
1. There was statistically significant anterior as well as anterolateral growth in the minor segment rather than the large segment of the maxilla from newborn to 2 years of age.
2. At 2 years of age, the maxillary alveolar arches became parabolic in shape due to the anterolateral growth of the large and minor segments of the maxilla guided by Hotz's plate.
3. From 2 to 7 years of age in the UCLP group, the large segment of the maxilla grew anteriorly and anterolaterally. Further, the minor segment of the maxilla was well developed like that of the non-cleft control group.
4. From 2 to 7 years of age, there was no statistically significant difference indicated between the groups in terms of the width of the maxilla.
5. The parabolic shape and size of the maxilla in the UCLP group were the same as that of the control group from the deciduous dentition to the early stage of mixed dentition.
From the above results, the study clarified that two-stage palatoplasty using Hotz's plate is significantly effective for maxillary growth in unilateral cleft lip, alveolus, and palate patients.View full abstractDownload PDF (5364K) -
Nobuyuki TANAKA, Takao MIYAMOTO, Yutaka KIMIJIMA, Kenichi SHIONOYA, Ma ...1996 Volume 45 Issue 3 Pages 240-247
Published: July 10, 1996
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSThe ultrastructures and expression of transferrin receptor (TfR), which is a potential marker for the proliferation activity, in addition to the histopathological investigation were examined to clarify the degree of malignancy in the tongue squamous cell carcinoma.
Tissue samples used in this study were obtained from the 41 patients with tongue squamous cell carcinoma at biopsy or operation. In addition to the examination of clinical features (T classification), pathological features (WHO classification), electronmicroscopic investigation, and immuno-histochemical investigation with TfR were performed, comparing the 22 non-metastatic cases with the 19 metastatic cases. Further, the localization of TfR was examined by the immunoelectronmicroscopic technique.
In the metastatic cases, numerous microvilli and a small number of desmosomes were found regardless of the width of the intercellular spaces. In the non-metastatic cases with wide intercellular spaces, few microvilli were found, and in the non-metastatic cases with the narrow intercellular spaces, numerous microvilli with a large number of desmosomes were observed. All the tumor tissues reacted strongly with the monoclonal antibody for TfR, but the degree of the reaction varied from case to case. The localization of TfR was recognized in the cell membrane, especially microvilli.
The results suggested that the features of microvilli might indicate the degree of the proliferation activity and the malignancy of the tongue carcinoma.View full abstractDownload PDF (14848K) -
Kazue YAMAGUCHI, Hirohito TAKEUCHI, Kazuma MASUMOTO, Kiyoshi ECHIGO, H ...1996 Volume 45 Issue 3 Pages 248-252
Published: July 10, 1996
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSOsteosarcoma is a highly malignant neoplasm of bone. It generally can be seen at the metaphyseal ends of the long bone from 10 to 30 years of age. In oral and maxillofacial surgery field, osteosarcoma is found more often in the mandible than in the maxilla, which has an incidence of only 1%. The peculiar radiographic features of osteosarcoma are sunburst spiculation and calcified body but not for the case of the jaws.
Here, a rare case of mandibular osteosarcoma is reported. The patient was a 49-year-old female. She first visited our hospital due to left side paralysis of the lower lip which lasted for three months. A well-circumscribed radiolucency was observed in the area beyond the left molar region, ramus and coronoid process. Under general anesthesia, the tumorous mass was extirpated and the marsupialization was done. The cystic lesion was clinically suspected prior to the initial operation. However, one and a half month later, it was found to be a osteogenic sarcoma by histopathological diagnosis. Therefore, surgical resection of the remaining mandible followed by immediate reconstruction by vasculized iliac bone graft was performed. The resulting bone defect after the initial operation had already been filled with fresh tumor tissue. This tumor tissue contained round or fibroblastic type cells with enlarged nuclei and showed invading growth character. Tumorous bone, osteoid formation, and bone destruction were also found in some places. After these operations, mandibular displacement has improved.
A rare case of osteogenic sarcoma that clinically showed cystic lesion or benign tumor features by a simple initial radiographic examination was experienced. However, a lesion like that in this case, found to be suspicious during operation, should be considered and treated as a malignant tumor.View full abstractDownload PDF (8069K) -
Tetsuya IMATANI, Toshikazu TAKAGI, Hiromasa HONMA, Kaori YAGO, Yutaka ...1996 Volume 45 Issue 3 Pages 253-257
Published: July 10, 1996
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSHepatitis C is an infectious disease with blood as the route of infection. It is well known that the disease may result from medical infection. It has become thought indispensable to recognize and identify the existence of colonies of the virus of infection by way of dental treatment.
The ratio of positive HCV antibody in 277 cases of inpatients who underwent surgery at Department of Dentistry and Oral Surgery, Keio University School of Medicine was examined. The background factors and the results of clinical chemical examination of HCV antibody-positive patients were analyzed. The cases with positive HCV antibody were 3.5% of the total. The average age of patients with positive HCV antibody was significantly greater than that of patients with negative ones. The blood chemical test revealed that the GOT, GPT, ZTT, and TTT in positive patients were abnormally higher than in negative ones.View full abstractDownload PDF (623K) -
Hisao SHIGEMATSU, Akira EDA, Kazuhiko SAITOH, Kiyoshi WATANABE, Hiroko ...1996 Volume 45 Issue 3 Pages 258-262
Published: July 10, 1996
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSThe purpose of this study was to survey past clinical observations of oral mucous cysts. One hundred eighty-four cases were obtained from the files of the 2nd Department of Oral Surgery, School of Dentistry, Meikai University between January 1982 and September 1995. The mucous cysts were classified as extravasation or retention cysts. Furthermore, they could also be classified into 3 types: type I (extravasation cyst) (58.7%), 'poorly defined cyst'; type II (extravasation cyst) (39.7 %), ‘well-defined cyst surrounded by granulation tissue’; and type III (retention cyst) (1.6%), ‘well-defined cyst surrounded by epithelium’. About 60% of the extravasation cysts occurred within the first twenty years of life. The lower lip, tongue, and floor of the mouth were frequent sites of extravasation cysts. The findings relative to age, sex, and location were very similar between type I and II cysts. According to these clinical findings and histopathological findings, it is considered that types I and II represent different stages of the same lesion. On the other hand, all of retention cysts (type III) occurred in older patients of 50 to 60 years old. Two of them arose in the buccal mucosa and one in the upper lip. None of them arose in the prevalent sites of extravasation cysts. These findings suggested that the retention cyst and the extravasation cyst are completely different lesions from each other. Treatment was mainly surgical removal with recurrence of the lesion in only 13 of the 181 extravasation cysts. None of the retention cysts recurred following complete local excision.View full abstractDownload PDF (3365K) -
Naohisa OKU, Masahiro UMEDA, Yoshiaki TAKE, Satoshi YOKOO, Hironari KA ...1996 Volume 45 Issue 3 Pages 263-268
Published: July 10, 1996
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSCorrelation between the method of resection of mandible and local recurrence was studied in 17 patients with squamous cell carcinoma of the floor of the mouth who underwent operation from 1980 to 1991, and the results were as follows
1. Marginal mandibulectomy was indicated when there was no resorption of the mandible on the X-ray film and the tumor was only slightly adherent to the mandible, while segmental mandibulectomy was indicated when the tumor was fixed to the mandible.
2. Local recurrence occurred in 4 of 17 patients.
3. Local recurrence occurred in patients with T2 or T3 tumors who underwent marginal mandibulectomy or no bone resection. Patients with T1 or T4 tumors, or those who underwent segmental mandibulectomy showed no local recurrence.
4. These findings suggested that segmental mandibulectomy should be performed when the tumor is adherent to the mandible.View full abstractDownload PDF (3858K) -
Katsuaki NEBASHI, Izumi MATAGA1996 Volume 45 Issue 3 Pages 269-285
Published: July 10, 1996
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSIn 18 cases that underwent renal transplantation (RT), an epidemiological study was carried out mainly on changes in the oral symptoms such as gingival hyperplasia, salivary, and taste dysfunction before and after RT. Then individual changes were clinically and histopathologically, in part, assessed. The results were as follows:
1. Hematoma previously observed on the oral mucosa disappeared after RT with improved anemic symptoms as well as dried lip and eye symptoms. Brown face characteristic of patients under hemodialysis was also improved.
2. Hematological examination revealed that anemia was improved with decreased serum electrolyte levels, including potassium and inorganic phosphorus, after RT. Furthermore, the PTH level decreased markedly.
3. As for changes that newly appeared after RT, gingival hyperplasia was observed in 6 out of 18 cases (33.3 %), which was histopathogically found to be fibrous hyperplasia in nature. Possible involvement of immunosuppressives or antihypertensives during pathogenesis was suggested.
4. Subjective symptoms of xerostomia, which some patients complained of before RT, were improved in all cases after RT. Increased salivary flow at rest was observed objectively after RT. Salivary scintigraphy, performed in some cases, revealed an improved oral excretion capacity after loading with 10 % citric acid.
5. Taste dysfunction observed before RT was improved in all cases after RT. A decreased threshold in 50 % of the cases was confirmed by a taste function test.
6. Suppressed sweating was also improved in all cases after RT.
7. Renal osteodystrophy (ROD) was obviously improved after RT with clearly depicted mandibular and pericondylar regions as well as recovered alveolar lumina dura on radiographs taken more than one year after RT.View full abstractDownload PDF (15234K) -
Fumihiro YOSHIKAWA, Tatsushi MATSUMURA, Yuriko TSUBAKIMOTO, Souichi IW ...1996 Volume 45 Issue 3 Pages 286-292
Published: July 10, 1996
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSThe clinical features of 45 patients with salivary gland carcinoma treated at the Second Department of Oral and Maxillofacial Surgery, Osaka University Dental School Hospital from 1980 to 1994 were retrospectively examined.
The 45 patients consisted of 14 patients with mucoepidermoid carcinoma, 14 with adenoid cystic carcinoma, 8 with adenocarcinoma, 6 with carcinoma in pleomorphic adenoma, 2 with acinic cell carcinoma, and 1 polymorphus low grade adenocarcinoma. The most frequently affected site was the palate, followed by the maxillary gingiva and the oral floor.
42 patients were treated in our clinic. Radical surgery was performed on 41 patients, and radiation therapy and/or chemotherapy were used concomitantly in some cases. The overall cumulative survival rate was 71.8 % at 5 years and 66.3 % at 10 years. The 5-year survival rate of the patients with mucoepidermoid carcinoma was 85.7 %, which was higher than that in any other subgroup of patients with carcinoma of the salivary glands. Chemotherapy as an adjuvant therapy with surgery was considered to be somewhat effective in patients with distant metastasis.View full abstractDownload PDF (889K) -
Yoshitaka HIBINO, Ken-ichiro HATA, Yasuo SUGIMURA, Chi-ying TSAI, Kuni ...1996 Volume 45 Issue 3 Pages 293-297
Published: July 10, 1996
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSIn the field of oral surgery, skin flaps have been commonly used for reconstruction of the oral mucosa after tumor resection. However, intra-oral skin flaps have many disadvantages such as hair growth and keratinization, Furthermore, most of these skin flaps consist of thick and mobile soft tissue. These problems made it difficult to treat by implant or removable prosthesis. Therefore, mucosal replacement of the skin by mucosal grafting was desired. However, collection of oral mucosal tissue as graft material was extremely limited.
The cultured epithelial sheets using human mucosal cells for such kind of mucosal reconstruction was studied. In this report, a case in which mucosal replacement was performed for an intra-oral skin flap as functional reconstruction using cultured mucosal epithelial sheet is presented and laboratory and clinical aspects of the investigations are described.View full abstractDownload PDF (8634K) -
Kenichi SHIONOYA, Sadao OKABE, Kazuhiro YAGIHARA, Teruo AMAGASA1996 Volume 45 Issue 3 Pages 298-301
Published: July 10, 1996
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSA case of a chondromyxoid fibroma of the maxilla is reported. A 60-year-old female visited the Department of Oral Surgery, Saitama Cancer Center with pain of the hard palate. Radiograms of the patient showed a well-defined, multilocular radiolucency in the maxilla. The lesion was clinically diagnosed as maxillary benign tumor and treated by enucleation under local anesthesia. Pathological examination revealed chondromyxoid fibroma. The clinical course for 3 and a half years since operation has been satisfactory.
Chondromyxoid fibroma is a rare benign bone tumor, which mainly occurs in the proximal metaphyseal end of long bones. Twenty cases of chondromyxoid fibroma in the oral cavity have been reported, including this case.View full abstractDownload PDF (3415K) -
A Report of a CaseKeiseki KANEYAMA, Shigeyuki FUJITA, Hiroaki YOSHIDA, Natsuki SEGAMI, M ...1996 Volume 45 Issue 3 Pages 302-305
Published: July 10, 1996
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSA case of adenoid cystic carcinoma of the left submandibular gland accompanied with calcification was reported. A 73-year-old female had an elastic, immovable diffuse swelling without pain in the left submandibular region for about twenty years. The tumor was completely resected, and radical neck dissection was done. Histological examination revealed that the tumor was mainly a tubular type. Immunohistochemical examination confirmed that duct-like structures in this tumor contained calcified deposits.View full abstractDownload PDF (6637K) -
Masahiro INAGUMA, Etsuaki TASHIRO, Kazue YAMAGUCHI, Hiroshi FUKUDA, Ke ...1996 Volume 45 Issue 3 Pages 306-310
Published: July 10, 1996
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSA case of localized amyloidosis of the maxilla was reported. A 72-year-old female was referred to our department on December 13, 1993 for investigation of buccal swelling
In this case, the extirpated mass of maxilla was revealed to be positive by Congo-red staining. Furthermore, amyloid P component could be identified by immunoperoxidase technique (PAP method), though amyloid A protein, AL protein (κ type, λ type), prealbumin, β2-microgloburin, and keratin could not be identified.
Immunohistochemically, it proved to be non-AA, non-AL, non-prealbumin, non-β2-microgloburin and non-keratin type. Electron microscopically, amyloid fibrils were clearly seen around collagen fibers and capillaries.View full abstractDownload PDF (9789K) -
Minoru NAKASE, Reiko TANAKA, Jouji NOMURA, Yuko KAWARADA, Hiroyo NISHI ...1996 Volume 45 Issue 3 Pages 311-315
Published: July 10, 1996
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSA clinicostatistical study on 100 cases of glossodynia, treated by the department of Oral and Maxillofacial Surgery, Mie University was performed between April 1993 and March 1995.
The male to female ratio was 1 to 3.2 (24 males, 76 females). Many cases were found in patients aged between 40 and 80 years. The apex of the tongue was the most frequent site, followed by the margins, the dorsum, and the whole tongue. Five males (20.8%) and 19 females (25.0%) were accompanied with xerostomia. There were 3 males (12.5%) and 8 females (10.5%) with dysgeusia. The prevalence of systemic disease was 70.0%, which was higher than the average for all outpatients (43.8%). Nine of 34 cases were found to have an iron deficiency. In all 25 cases examined, zinc was within the normal range. As for treatment of glossodynia, combination therapy was more effective than single therapy.View full abstractDownload PDF (2221K) -
Stellate Ganglion Block for Two Cases of Facial Nerve Palsy after Sagittal Splitting Ramus OsteotomyYoshimasa KITAGAWA, Kaihei HAYASHI, Hironori MORIHIRO, Toshiyuki OGASA ...1996 Volume 45 Issue 3 Pages 316-320
Published: July 10, 1996
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSFacial nerve palsy following sagittal splitting ramus osteotomy (SSRO) is a rare but serious complication. Two cases of peripheral facial nerve palsy several days after orthognathic surgery, treated successfully with stellate ganglion blocks (SGB), were described. Case 1: A 17-year-old female underwent bilateral SSRO. Six days after the operation, right facial palsy was appeared. To improve the palsy, SGBs were performed, and the palsy was completely remitted. Case 2: A 19-year-old female underwent SSRO. Left facial palsy appeared on the eighth postoperative day. Palsy was almost remitted by 32 SGBs eight months after the operation. In the present cases, facial palsy might have arisen due to ischemic change of the nerve, which was caused by hematoma, edema, swelling, and tissue traction. SGB has been found to be effective in the treatment of facial palsy after SSROView full abstractDownload PDF (5563K)
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