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Volume 55, Issue 4
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[in Japanese]2006 Volume 55 Issue 4 Pages 223-230
Published: September 10, 2006
Released on J-STAGE: January 31, 2011
JOURNAL FREE ACCESSDownload PDF (997K) -
Hideki GOTO, Tadaharu KOBAYASHI, Yoshiyuki TAKATA, Naoya IZUMI, Toshio ...2006 Volume 55 Issue 4 Pages 231-240
Published: September 10, 2006
Released on J-STAGE: January 31, 2011
JOURNAL FREE ACCESSThis study examined the diagnostic ability and difficulties of pulse oxymetry as a device to screen sleep respiratory disturbances.
Seventy-one subjects participating in this study were examined in the hospital by all-night polysomnography (PSG) and a pulse oxymeter for possible sleep respiratory disturbances. The following three items were compared to estimate the diagnostic performance of the pulse oxymetry: the apnea hypopnea index (AHI), which is calculated from PSG results, representing the hourly figures of apnea and hypoventilation; the oxygen desaturation index (ODI), calculated from pulse oxymetry results, indicating the hourly figures of the change in oxygen saturation of blood; and CT90, the ratio between the minimum blood oxygen saturation and the period of time that blood oxygen saturation dropped below 90%.
AHI strongly correlated with ODI. Based on AHT 20 as the positive standard, the sensitivity and the specificity of diagnostic performance were 83.7% and 95.5%, respectively, with 4% ODI greater than ten as the diagnostic index. These results suggest that pulse oxymetry is a useful screening procedure due to its superior diagnostic performance.View full abstractDownload PDF (1219K) -
Goichi TSUKAMOTO, Yasuto YOSHIHAMA, Tatsuo ONO, Shohei DOMAE, Toshiko ...2006 Volume 55 Issue 4 Pages 241-245
Published: September 10, 2006
Released on J-STAGE: January 31, 2011
JOURNAL FREE ACCESSThe purpose of this study was to analyze a pattern for occurrence of keratocystic odontogenic tumors (KCOTs) in basal cell nevus syndrome (BCNS). The materials consisted of ten patients (four males, six females) with 57 KCOTs in BCNS. In radiographic examination, all of the tumors were divided into dentigerous and primordial variants. The age of the patient when each tumor was first identified on panoramic radiography or computed tomography was defined as the age when it occurred, for convenience. The mean age at occurrence of the dentigerous type was significantly younger than that of the primordial type. Twenty-two of the 25 third molars that emerged on the radiography were related to the dentigerous tumors. In half of the ten BCNS patients, every third molar was related to the dentigerous type. These findings suggest that impacted third molars should be observed for tumor formation from their early stage.View full abstractDownload PDF (1659K) -
Makoto TOIDA, Keizo KATO, Kazuhiro YONEMOTO, Hiroki MAKITA, Daijiro HA ...2006 Volume 55 Issue 4 Pages 246-252
Published: September 10, 2006
Released on J-STAGE: January 31, 2011
JOURNAL FREE ACCESSCevimeline hydrochloride hydrate (CHH) shows excellent efficacy for the treatment of xerostomia in Sjögren's syndrome (SS) patients, with considerably frequent adverse effects consisting mainly of digestive symptoms.
In the present study, the efficacy of CHH and the status of adverse effects were compared among the following three groups of SS patients with xerostomia, each of which had similar clinical backgrounds: Group A, which received 30mg of CHH three times daily for seven weeks (n=19); Group B, which received 30mg of CHH once daily for the first week and twice daily for the following six weeks (n=22); and Group C, which received the same dosage of CHH as Group B, except for the addition of 100mg of trimebutine maleate, twice daily for seven weeks (n=21).
The three groups showed similar significant improvements in both salivary flow rate (p<0.01) and subjective symptoms of dryness of the mouth (p<0.01). Adverse effects were significantly less frequent in Groups B(27%) and C (24%) than in Group A (63%)(p<0.05). Moreover, the period from the start of dosage to the occurrence of adverse effects was significantly longer in Groups B (19.5±15.3 days) and C (20.3±12.6 days) than in Group A (6.5±6.2 days)(p<0.05). Thus, it is suggested that the methods in Groups B and C are useful to minimize adverse effects of CHH without any significant reduction of efficacy of this drug.View full abstractDownload PDF (1219K) -
Erina NAKAMURA, Hitoshi ISHIKAWA, Katsuya AIKO, Yutaka KOBAYASI, Norih ...2006 Volume 55 Issue 4 Pages 253-258
Published: September 10, 2006
Released on J-STAGE: January 31, 2011
JOURNAL FREE ACCESSHistorically, arsenic trioxide (AT) was commonly used in endodontic treatment because it acts quickly and devitalizes the pulp within two days. However, it is cytotoxic to gingiva and bone. If it diffuses out of the cavity it can readily cause widespread necrosis of gingiva and bone, which can lead to osteomyelitis of the jaws. This article presents two cases of osteonecrosis of the jaws caused by leakage of AT. Case 1: A 74-yearold male was referred to our department complaining of pain of the left maxilla following extraction of his first maxilla molar on the left side by a private practitioner three months earlier. Case 2: A 39-year-old female was referred to our department complaining of impairment of sensation in the left lower lip following root treatment of her second mandibular molar on the left side by a private practitioner. AT preparation had been used in both these cases two months earlier. We performed sequestrectomy under local anesthesia in these cases.View full abstractDownload PDF (4379K)
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