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Volume 20 (1981)
- Issue 4 Pages 607-
- Issue 3 Pages 483-
- Issue 2 Pages 185-
- Issue 1 Pages 1-
Volume 20, Issue 4
Displaying 1-10 of 10 articles from this issue
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Tadashi AOKI, Kazuko IMAMURA, Hiroko MOTOE, Hiroichi SUZUMURA1981 Volume 20 Issue 4 Pages 607-614
Published: 1981
Released on J-STAGE: January 25, 2011
JOURNAL FREE ACCESSThe current study was carried out to investigate the effects of IUD on the endometrium and to establish a rational means of cytological management of women wearing IUD. In the groups before (control) and after IUD insertion, cytological examinations were made at regular intervals in 130 women wearing IUD, along with periodic check-ups of the intrauterine state and side effects of IUD according to the guiding principle of the Ministry of Welfare of Japan.
The samples in this study were obtained from the vaginal pool, endocervical scraping, endometrial aspiration, and touch smears of the removed IUD. Foreignbody type giant cells, calcified bodies and atypical endometrial cells were detected in twenty, nine and nine cases respectively in the IUD wearing group, but none of them found in the control group.One of nine cases with atypical endometrial cells showed the cellular features of enlarged nuclei, hyperchromasia, macronucleoli and cellular groupings, simulating adenocarcinoma. Six of them were obtained from endometrial aspiration smears.
It is recommended that cytological examinations including endometrial aspiration smear be performed on the women wearing IUD.View full abstractDownload PDF (4466K) -
Yahachi YAGI, Masao KASAHARA, Yoshihisa WATANABE1981 Volume 20 Issue 4 Pages 615-626
Published: 1981
Released on J-STAGE: January 25, 2011
JOURNAL FREE ACCESSMammary tumors were studies, aiming at elucidation of the borderline of benign and malignant findings from the standpoint of cytological diagnosis, using 3 kings of hydrolases, i. e. Alkaline phosphatase, Acid phosphatase, and β-Glucuronidase, concomitantly with the general Papanicolaou method. The materials were the aspiration smear from the tumor lesion, abrasion cytology, and inprint specimens from the postoperated and biopsied mammary tumors.
Examinations at tissue level were conducted in the first experimental group consisting of 15 patients with malignant tumors and 15 subjects without cancer, and also examinations were carried out, concomitantly using cytology and histology in the second experimental group consisting of 13 caneros patients, i. e. 12 cases with infiltration cancer and 1 case with non-infiltration cancer, and 13 non-cancerous patients.
As a result Alkaline phosphatase reactions showed negative results of all cancerous lesions irrespective of the tissue pattern of malignant tumors, cytodiagnostically the majority of malignant atypical cells due to the Papanicolaou method showed the disappearance and marked decrease of the activity. In 1 case of non-infiltration cancer, cells with weak activity existed maixing. In non-cancerous cases obviously positive reactions were observed irrespective of mastopathy, fibroadenoma, etc.
The reactions of Acid phosphatase, β-Glucuronidase, etc. hardly showed any difference in the activity of atypical cells between cancerous cases and non-cancerous cases, and histologically strong activity was observed in the epithelium of apoerine metaplasia, adenosis, etc.
Thus, it has been concluded that concerning the diagnosis of benign and malignant atypical cells in mammary tumors, the concomitant use of the usual Papanicolaou method with Alkaline phosphatase reaction is one of the significant methods to elucidate the borderline lesion.View full abstractDownload PDF (10809K) -
Takashi YAMADA, Toyohiko SATOU, Yohko SUZUKI, Shohei HORIE, Koichiro S ...1981 Volume 20 Issue 4 Pages 627-637
Published: 1981
Released on J-STAGE: January 25, 2011
JOURNAL FREE ACCESSRetrograde cytologic and histologic examinations were carried out on 31 cases with chest tumors in which cytologic specimens unusual cytologic features had been observed. These cases were selected from ca. 10, 000 cases examined cytologically during past several years. The unusual findings are classified as follows; 1) Three lung cancers from which specimens two different kinds of cancer cells were observed, including a double primary lung cancer. 2) Thirteen primary rare tumors. 3) Seven metastatic non-epithelial tumors. 4) Three malignant tumors invading directly from the surrounding tissue or organs to the lungs or pleura. 5) Five occult active cancers metastasized into the lungs.
The cytologic and histopathologic features of these tumors were demonstrated and their clinicopathologic bases were discussed.View full abstractDownload PDF (22192K) -
Yasuki SAITO, Anusak YIENPRUGSAWAN, Eiichi AKAOGI, Hideichi SUDA, Hiro ...1981 Volume 20 Issue 4 Pages 638-647
Published: 1981
Released on J-STAGE: January 25, 2011
JOURNAL FREE ACCESSCancer cell clusters in sputum from 35 pulmonary adenocarcinoma cases were analyzed numerically. For convenience, single cells were counted as one cluster. After fixation in Saccomanno's solution (50% ethanol, 2% carbowax 1540) sputum specimens were homogenized from a minimum condition at 1, 800 r. p. m. for 3 sec to a maximum at 18, 000 r. p. m. for 1, 000 sec. The degree of disaggregation of cancer cell clusters in various homogenized conditions was estimated accurately by the ratio of total no.of clusters to total no. of cells (n/N). When specimens were homogenized at 18, 000 r. p. m. for 30 sec, the n/N ratio of poorly differentiated adenocarcinoma cases was higher than that of well or moderately differentiated cases (P<0.01). The following formula can be used to ascertain the patterns of freqrency distribution of observed adenocarcinoma cell clusters; here, the patterns of disaggregation are provided by the ratio n/N.The goodness-of-fit test approved 63 out of 76 specimens with the statistical significance of 0.05 level.
ei=n{(1-g(i-1)/N)n-1-(1-g(i)/N)n-1}where g (i) =2.6 (i-0.4) 0.6, i=1, 2, 3, ...N g (0) =0
i=No. of cells in a cluster ei=Expected no. of clusters n=Total no. of clusters N=Total no. of cellsView full abstractDownload PDF (1621K) -
Hirofumi KUDOH, Akira KAMASAKO, Yasuo IITSUKA, Shigemasa KOGA, Yoshito ...1981 Volume 20 Issue 4 Pages 648-656
Published: 1981
Released on J-STAGE: January 25, 2011
JOURNAL FREE ACCESSThe cytologic specimen prepared by imprinting the biopsy specimen was used for the cytology of gastric malignancy during the past 3 years, and the results of both histology and cytology using the identical materials, were comparatively examined. The subjects were a total of 163 cases, consisting of 115 cases of advanced gastric cancer, 45 cases of early gastric cancer, and 3 cases of gastric sarcoma. In the 115 cases of advanced gastric cancer, 88% was diagnosed as positive in cytology, 87% as positive in histology, and 90% as positive in either cytology or histology. In the early gastric cancer the positive diagnoses were obtained in 78% by cytology, 69% by histology, and 82% by the concomitant use of cytology and histology. In all of the 163 cases, 124 cases (76%) were diagnosed as positive in both of cytology and histology, 14 cases (8%) as positive in only cytology and 6 cases (4%) as positive in only histology, but 19 cases (11%) were diagnosed as negative in both of cytology and histology. Thus cytology was more advantageous than histology in the diagnosis of gastric malognancy, but the concomitant use of cytology and histology further increased the rate of positive diagnosis. The reason for this seems attributable to that some small amounts of malignant cells which cannot be diagnosed as positive in histology, can be diagnosed as positive in cytology. On the other hand, in case one was diagnosed as negative, the number of specimens tended to be small, and accordingly it seems that a larger number of specimens should be taken.View full abstractDownload PDF (10623K) -
Kunihiko MUTO, Etsuo TAKADA, Katsumasa YOKOTA, Shoichi IKEGUCHI, Shige ...1981 Volume 20 Issue 4 Pages 657-669
Published: 1981
Released on J-STAGE: January 25, 2011
JOURNAL FREE ACCESSDuring last 3 years from January 1978, ultrasonically guided percutaneous aspiration cytology was performed in 55 patients with abdominal tumor. The cytologic result for 45 cases of tumor in liver, pancreas and gallbladder was reported in this paper.
1) The positive result of cytologic examination by this technique was as follows:(1) liver tumor including primary and metastatic; 100% in 10 cases, (2) pancreas tumor; 90% of positive rate in 9 cases out of 10, (3) gallbladder tumor; 100% in 4 cases of gallbladder carcinoma, 17 cases of benign gallbladder out of 21 were diagnosed as benign tumor correctly.
2) One of false negative case in pancreas tumor was carcinoma of 1.5×2.0cm in size. Acurrate technique of puncture is necessary for tumor in smaller size.
3) One case of gall peritoritis as the complication of this procedure was encountered in the puncture of gallbladder. The other complications was not observed among times of manipulation.
4) Further improvement of equipment of ultrasonography in the precise detection of smaller tumor is expected.View full abstractDownload PDF (26811K) -
Masayuki SOMA, Chieko ISHIWATA, Takashi TSUKADA, Fumio SHIBATA, Emiko ...1981 Volume 20 Issue 4 Pages 670-674
Published: 1981
Released on J-STAGE: January 25, 2011
JOURNAL FREE ACCESSThe present report deals with a 78-year-old woman who had a giant cystic ovarian theca cell tumor (2, 200gr).
The cytohormonal pattern on the vaginal smear showed hyperactivity of estrogens; that is maturation index (MI) of 0/18/82 and eosinophilic cell index (EI) of 79/21.
The imprint smears of theca cell tumors were characterized as showing free nuclei which were remarkably even in shape, size and chromation pattern (fine granule).View full abstractDownload PDF (7504K) -
Especially its Findings through Imprint CytologyKozo ITOH, Kazuko OUCHI1981 Volume 20 Issue 4 Pages 675-681
Published: 1981
Released on J-STAGE: January 25, 2011
JOURNAL FREE ACCESSA case of ovarian endodermal sinus tumor (EST) following an operation on thyroid carcinoma is reported. The imprint cytology findings of EST were as follows:
1. The cell shapes were mostly cuboidal or columnar.
2. The various vacuoles were consistently seen in the cytoplasms, which were stained pale green by Papanicolaou's stain, and hyaline globules were sometimes seen also. The nuclear shapes were round or oval. The nuclear: cytoplasmic ratio was large, and the chromatin pattern was fine.
3. The nucleoli were prominent and enlarged. There were usually 2 or 3 in the nuclei.
The authors also checked for alpha feto protein (AFP) in the serum from the patient as a post-operative marker, in order to determine the possibility of a recurrence or metastasis, and this was also deemed useful in ascertaining the effect of anti-cancer agents on EST.View full abstractDownload PDF (10272K) -
Binzaburo MUROHISA, Junji YOSHINO, Masayuki UCHIMURA, Yoshihiro MUTO, ...1981 Volume 20 Issue 4 Pages 682-689
Published: 1981
Released on J-STAGE: January 25, 2011
JOURNAL FREE ACCESSThe 48 year-old man was admitted under diagnosis of diabetes mellitus.The plain abdomen X-ray films showed calcifications in the pancreas, and pancreozyminsecretin test revealed a senere depression of pancreatic function. The concomitant cytologic examination revealed a few malignant cells in the duodenal juice.
A laparotomy was performed for suspicion of carcinoma of the pancreatic head. The main pancreatic duct was markedly dilatated, and many small calculi were palpable. By intraoperative cholangiography, a part of the main duct of the pancreatic head was narrowed, and needle aspiration cytology was performed around the lesion several times. Malignant cells were again found in a part of head, and therefore a pancreatoduodenectomy was performed.
A tiny papillary cancer, several mm in diameter, was found in the constricted portion of the main pancreatic duct.
The patient had been fairly well for successive four years, but diabetic disturbance could be not always regularly controled.
It was an unexpected event that he died of cancer apparently recurred, short by after Virchow's metastasis had developed at about four years after the operation mentioned above. The autopsy examination revealed a cancer, involved in almost of the pancreas remnant associated with wide spread metastasis all over the pancreatic body.
It seems probable that the cancer observed at autopsy is likely of different origin from the microcarcinoma of the pancreatic head detected by cytologic examinations and removed operatively. Otherwise, it can not be resonablly explained of this fact that the patient has been survived for more than four years after the operation under fairly well condition.View full abstractDownload PDF (12405K) -
1981 Volume 20 Issue 4 Pages 715-812
Published: 1981
Released on J-STAGE: January 25, 2011
JOURNAL FREE ACCESSDownload PDF (15277K)
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