The Kurume Medical Journal
Online ISSN : 1881-2090
Print ISSN : 0023-5679
ISSN-L : 0023-5679
29 巻, 3 号
選択された号の論文の7件中1~7を表示しています
  • ARATA SUGITA, FUMIHIDE ABE, HISAHARU YOSHIOKA, RISEI ISHIBASHI
    1982 年 29 巻 3 号 p. 101-105
    発行日: 1983/04/15
    公開日: 2010/02/08
    ジャーナル フリー
    The phagocytic capability of iris fibroblasts was investigated electronmicroscopically. Gold-sol particles, which were injected into the anterior chamber as lysosomal markers, were selectively taken up by fibroblasts and macrophages in the iris stroma. The cytoplasm of the gold-sol-phagocytized fibroblasts displayed a strong histochemical reaction to acid phosphatase. A reaction product representing acid phosphatase activity was not only observed in the cisternae and vesicles of the well-developed Golgi complex but also in the inclusions containing the gold-sol particles. This indicates that the iris fibroblasts have phagocytic capabilities under appropriate conditions.
  • I. Histological Observations on the Tissue Reactions to S. japonicum Eggs and Lycopodium Powder
    MINORU MIYASATO, HIROKI IIDA, NAOKI YOSHIOKA, HIROSHI TSUTSUMI
    1982 年 29 巻 3 号 p. 107-116
    発行日: 1983/04/15
    公開日: 2010/02/08
    ジャーナル フリー
    Granuloma formation around the lycopodium was macroscopically and microscopically compared with the granuloma around Schistosoma japonicum eggs to determine whether lycopodium power could be used as a substitute for the eggs. The eggs were isolated from the liver and intestine of rabbits 8 weeks after infection with S. japonicum. Approximately 100, 000 eggs or 200, 000 lycopodia were injected into the lungs of each rabbit through the auricular vein. The lungs were removed 14, 28, 84 and 86 days after the injection. Paraffinembedded sections of the lungs were stained with hematoxylin-eosin, azanmallory and luna stains. Tubercula were grossly observed in the lungs of 4 rabbits at 14 days; one of which was after a lycopodia injection. The characteristics of the lycopodium tuberculum were similar to the characteristics of the egg tuberculum. Microscopically, two types of reactions developed around the eggs. One was very severe and the other was mild or absent. The severe granulomas were large in size at 14 days, but they gradually became smaller, although they were still present after 86 days. The granulomas with mild reactions were very small in size at 14 days, diminished in size with time, and disappeared by 86 days. With all types of injections, the majority of the inflammatory cells in the granuloma were mononuclear cells with some eosinophils and pseudoeosinophils. Giant cells were often observed at 14 days and they slowly increased in number. The giant cells were observed in most of the granuloma at 86 days. Scar formation was seen at 28 and 86 days. The charac teristics of the lycopodium granuloma were very similar to the characteristics of the egg granuloma except that lycopodium granuloma was smaller in size and had more giant cells, the rate of destruction and absorption of the giant cells in the tissue was also slower. Although the lycopodia did not induce as severe a reaction as the eggs, it can be assumed that the lycopodium could be used as substitute for the S. japonicum eggs under certain conditions.
  • SHIGERU YAMAMOTO, HIDEFUMI KABUTA, KANJI IKEUCHI
    1982 年 29 巻 3 号 p. 117-122
    発行日: 1983/04/15
    公開日: 2010/02/08
    ジャーナル フリー
    Eight r mutants, which are defective in fusion function, were isolated following BURR mutagenesis of a syncytial strain of herpes simplex virus type 2 (HSV 2). Most of the mutant pairs complemented each other and resulted in cell fusion, thus the r mutants could be classified into seven complementation groups. R mutants belonging to different complementation groups recombined effectively with each other, making it possible to construct a linkage map based on fusion function.
  • TOSHIMITSU SHINGU, TAKAHIRO UCHIDA, MASUJI NISHI, KAZUO HAYASHIDA, SEI ...
    1982 年 29 巻 3 号 p. 123-125
    発行日: 1983/04/15
    公開日: 2010/02/08
    ジャーナル フリー
    Seventeen hospital employees were inoculated with 40 -μcg hepatitis B vaccine as a part of a phase 1 trial in Japan. More than 90 per cent of the subjects developed antibodies against HBsAg after two doses of the vaccine. The third dose had a booster effect. Seven of the 16 vaccinated women experienced menstrual abnormalities after the first and/or second inoculation. These included hypomenorrhea, too short menstruation, oligomenorrhea and polymenorrhea. One subject also suffered from acne after the third inoculation. These abnormalities may be side effects of the hepatitis B vaccine which have not been reported previously.
  • SEIICHIRO YAMASAKI, SHIZUMA EGASHIRA, MICHIHIRO KOGA, HARUO AKAGAWA, S ...
    1982 年 29 巻 3 号 p. 127-140
    発行日: 1983/04/15
    公開日: 2010/02/08
    ジャーナル フリー
    A direct colorimetric assay of ammonia liberated after a guanase reaction with 8 -azaguanine as substrate was tested using a guanase-assay kit (Maruho Co., Ltd.). The clinical importance of the guanase activity in blood was studied. The method for determination of guanase activity in the blood with this kit was simple, sensitive and accurate indicating that this kit could be useful as a routine test. The level of guanase activity of 775 normal subjects was 0-3.8 IU/L. A good correlation between guanase and transaminase in the blood was obtained in patients with hepatitis. In normal subjects there was not a good correlation between the two enzymes. To prevent the development of hepatitis after a blood transfusion, it was found that the determination of guanase activity in blood was more useful than the screening of GOT and GPT activities. Sixty-one per cent of the subjects developed hepatitis after blood transfusion. In a group which received blood containing less than 2.0 IU/L of guanase activity, less than 16.7% developed hepatitis. For a group which was transfused with blood containing more than 2.1 IU/L of guanase activity, 80% of the patients developed hepatitis. These results indicate that the determination of guanase activity is a useful test to determine the probability of transmitting hepatitis. To avoid the transmission of hepatitis during a blood transfusion, it is necessary to use blood containing low guanase activity.
  • HIROSHI TAIRA
    1982 年 29 巻 3 号 p. 141-155
    発行日: 1983/04/15
    公開日: 2010/02/08
    ジャーナル フリー
    The frequency of Heroin and LSD related crimes began to increase in 1971. It reached a peak of 259 cases in 1973, and then gradually decreased in subsequent years. Marijuana related crimes first occurred in 1968. There were 73 cases in 1972. This increased to 162 by 1978. The frequency of marijuana crimes had a strong positive correlation with the number of U. S. servicemen in Okinawa. Heroin dependence was first observed in 1972 with 36 cases, reached a peak in 1973 with 54 cases and then gradually decreased to six cases in 1976. Most of the drug dependence cases including the author's clinical cases involved juvenile bar hostesses who were either in contact with or had cohabited with U. S. servicemen. The types of drugs, and the motivation and distribution in dependence resembled the United States pattern and had a strong correlation with the Vietnam War.
  • A Preliminary Report
    MINORU HIRANO, HIROSHI OHKUBO, SHIGEJIRO KURITA, SHIGENOBU MIHASHI
    1982 年 29 巻 3 号 p. 157-162
    発行日: 1983/04/15
    公開日: 2010/02/08
    ジャーナル フリー
    For selected cases of carcinomas of the oral cavity and mesopharynx, a combined laser and radiation therapy has been applied in our department since 1980. This paper describes its technique, rationale and preliminary results. Ten patients with carcinoma of the tongue, 2 with carcinoma of the cheek mucosa and 1 with carcinoma of the mesopharynx were treated with this technique. Follow-up ranged 2 months to 3 years and 1 month. None of the 13 patients has developed recurrence.
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