Prediction of the histology of MPGN was performed without doing a renal biopsy by a univariate and multivariate analysis of three histological groups in nephrotic children: membranoproliferative glomerulonephritis (MPGN, N=13), proliferative glomerulonephritis (PGN, N=11) and minimal change nephrotic syndrome (MCNS, N=10). If the Y value of the following equation exceeded 0.41, the probability of MPGN was very high with a misdiscrimination rate of 4.8 %. A Y value less than 0.41 eliminated the possibility of MPGN.Y=0.1738X
17-0.0119X
19-0.1808X
23+0.4606X
27-0.0743X
32+0.2740X
35+0.4591(X
17=serum Ca, mg/dl; X
19=serum C3, mg/dl; X
23=serum total protein, g/dl; X
27=serum beta globulin, g/dl; X
32=hematuria by paper test, 0=negative, 1=+, 2=Y, 3=Y, X
35=presence of urinary granular cast, 0=none, 1=present)
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