The Kurume Medical Journal
Online ISSN : 1881-2090
Print ISSN : 0023-5679
ISSN-L : 0023-5679
4 巻, 3 号
選択された号の論文の6件中1~6を表示しています
  • YOH NAKAGAWA, MASAHISA SHINGU, TAMOTSU NAKASHIMA
    1957 年 4 巻 3 号 p. 115-126
    発行日: 1958/02/01
    公開日: 2010/02/08
    ジャーナル フリー
    It has been known for several years that a number of neurotropic viruses cause hemagglutination of erythrocytes(1)-(13), and moreover, that varying the various conditions of hemagglutination, the spectrum of virus hemagglutination has been widely spread. Rheims et al(14) reported that trypsin-trseated human group O red cells increased their agglutinability by mouse lung infected with PR 8 influenza virus, and Morris(15) investigated that mouse encephalomyelitis virus (GDVII strain) agglutinated well human group O erythrocytes at 20 C in the presence of trypsin. In this laboratory also were obtained the similar results to those of Morris with trypsin and the following conclusions were reached that the mechanism of hemagglutination enhancement by trypsin seemed to be attributed to the increase of agglutinability of trypsin-treated red cells under a small amount of viruses, and on the other hand, to the digestion of hemagglutination inhibitors contained in mouse brain by the enzyme(16).The present paper deals with enhancement of virus hemagglutination by the treatment of red cells with ficin, an intracellular plant protease, and by the treatment of virus suspension with the same enzyme.
  • I. THE FINE STRUCTURE OF FROG RETINA
    EICHI YAMADA, M. D.
    1957 年 4 巻 3 号 p. 127-147
    発行日: 1958/02/01
    公開日: 2010/02/08
    ジャーナル フリー
    The retina of frog, Rana pipiens, is studied with electron microscope. The observations are summarized as follows :1. The lamellar body in the rod outer segments divides into several columnal lobules. Each lobule shows a characteristic pile of the flat sacs, so called rod sacs.2. The connection between the segments is a short narrow stalk and represents a ciliary nature.3. The ciliary filaments extend a certain distance into the outer segment, but no direct connection is observed between the filaments and rod sacs.4. The numerous mitochondria accumulate in the distal portion of the inner segment and arrange in such a way as showing an orientation toward the basal body of connecting cilium.5. The endoplasmic reticulum of the characteristic arrangement and the Golgi bodies are recognized in the inner segment.6. The synapses between visual and bipolar cells, and between bipolar and ganglion cells are described.7. The nervefiber layer is composed of bundles of numerous unmyelinated nerve fibers and of glial element of large quantity which embeds the nerve fibers.8. The glial element is recognized in all layers of retina and the local modifications and some fine structure of the element are demonstrated.9. Some physiological points of these structures are discussed.
  • EICHI YAMADA, M. D., TOYOKO MUTA, B. S., AKIRA MOTOMURA, M. D., HIDETO ...
    1957 年 4 巻 3 号 p. 148-171
    発行日: 1958/02/01
    公開日: 2010/02/08
    ジャーナル フリー
    The electronmicroscopy of tissues and cells has added many new findings to our concept about their structures and is bringing the great contribution to the modern cytology. Although the fine structure of oocytes was also studied by this method, the materials used, in the studies so far published, were the ones of invertebrate (1) (2) (3) (4) (20) (22) (23) and amphibia (14), and the detailed studies on the mammalian oocytes were not published yet. At the present work, the various developmental stages of oocytes are recognized within the sections of mouse ovary. Their fine structures, especially the characteristic modification of mitochondrial structure and the peculiar bodies composed of numerous vesicular components, are reportd in this paper.
  • II. REPORT. THE INHIBITORY EFFECT OF BACTERIAL SUBSTANCES RELATED E. COLI ON THE NEUROTROPIC VIRUS INFECTION
    MASAHIRO NAKAMURA, YOH NAKAGAWA
    1957 年 4 巻 3 号 p. 172-188
    発行日: 1958/02/01
    公開日: 2010/02/08
    ジャーナル フリー
    In the previous report (1) (2), an exploratory experiment to ascertain the presence or absence of similar modifying effect of bacteria or bacterial substances on the course of neurotropic virus infection to that of pneumotropic virus in the natural state has been studied. The results obtained indicated that there are some bacteria having the inhibitory or stimulating effect on the neurotropic virus infection.It is the purpose of this paper to report in detail the mode of the effect of E. coli which is choosed among the bacteria having the inhibitory effect on the virus infection in the previous exploratory experiment.
  • III. REPORT. THE MODE OF THE INHIBITORY EFFECT OF BACTERIAL SUBSTANCES RELATED E. COLI ON THE NEUROTROPIC VIRUS INFECTION STUDIED IN THE SUSPENDED TISSUE CULTURE
    YOH NAKAGAWA, MASAHIRO NAKAMURA
    1957 年 4 巻 3 号 p. 189-196
    発行日: 1958/02/01
    公開日: 2010/02/08
    ジャーナル フリー
    The E. coli was selected among the bacteria having inhibitory effect described in the previous reports (1) (2), and the experiments concerning the inhibitory effect of E. coli on the GDVII strain of mouse encephalomyelitis virus (GDVII virus) were investigated in detail (3) (4). The results obtained were the following data: the administration with E. coli before virus inoculation was effective on the inhibition of the infection with the GDVII virus, but when the E. coli was given to the mice follo wing the virus infection the effect of the bacteria was not evident; it was most significant in the case of the same route of administration with the bacteria and the virus; the bacteria itself had not direct virucidal activity; the effect of the bacteria was not related with the antibody against this bacteria; and no evidence of inapparent infection in the survival mice was presented. Therefore it would be assumed that the inhibitory effect of E. coli on the virus infection might prevent the invasion or penetration of the virus into the susceptible cells.The purpose of this paper is to report a part of the kinetics of the inhibitory effect of E. coli on the virus infection by using the suspended tissue culture method which is available to clarification of the mechanism of the effects. It is favorable for an introduction of the tissue culture into series experiments that the effect of E. coli exsisted in the bacterial cells and was thermostabile.
  • KEN NODA
    1957 年 4 巻 3 号 p. 197-203
    発行日: 1958/02/01
    公開日: 2010/02/08
    ジャーナル フリー
    The internal mechanism for producing the vivid spontaneous regular rhythm was experimentally investigated.Everywhere in the cortical region is capable of oscillating the spontaneous regular rhythm similarly, and there exists no localizing difference from place to place in oscillating pattern. However, the difference of response from individual to individual may be caused by respective ontogenical factors.That the electrically oscillating system of nervous tissue is constituted by both the self-re-exciting activity remaining after neurone chain activity evoked by sensory stimuli and the modifying factors of various kinds of impulse inflow to this self-reexiting chain system is assumed by the author.Thanks are expressed to Prof. K. Suenaga M. D. for his helpful suggestions.
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